Genetic Aspects and Molecular Testing in Prostate Cancer: A Report from a Dutch Multidisciplinary Consensus Meeting

Autor: Niven Mehra, Iris Kloots, Michiel Vlaming, Shafak Aluwini, Els Dewulf, Daniela E. Oprea-Lager, Henk van der Poel, Herman Stoevelaar, Derya Yakar, Chris H. Bangma, Elise Bekers, Roderick van den Bergh, Andries M. Bergman, Franchette van den Berkmortel, Steve Boudewijns, Winand N.M. Dinjens, Jurgen Fütterer, Tom van der Hulle, Guido Jenster, Leonie I. Kroeze, Michel van Kruchten, Geert van Leenders, Pim J. van Leeuwen, Wendy W.J. de Leng, R. Jeroen A. van Moorselaar, Walter Noordzij, Rogier A. Oldenburg, Inge M. van Oort, Irma Oving, Jack A. Schalken, Ivo G. Schoots, Ed Schuuring, Robert J. Smeenk, Ben G.L. Vanneste, Erik Vegt, André N. Vis, Kim de Vries, Peter-Paul M. Willemse, Maurits Wondergem, Margreet Ausems

Publikováno v: European Urology Open Science, Vol 49, Iss , Pp 23-31 (2023)

Background: Germline and tumour genetic testing in prostate cancer (PCa) is becoming more broadly accepted, but testing indications and clinical consequences for carriers in each disease stage are not yet well defined. Objective: To determine the con

Externí odkaz: https://doaj.org/article/6f52ae4fdd99475585e6ab93b18449bb

Estetrol Prevents Hot Flushes and Improves Quality of Life in Patients with Advanced Prostate Cancer Treated with Androgen Deprivation Therapy: The PCombi Study

Autor: Yvette Zimmerman, Mark Frydenberg, Hendrik van Poppel, R. Jeroen A. van Moorselaar, Erik P.M. Roos, Diederik M. Somford, Ton A. Roeleveld, Tjard D. de Haan, Harm H.E. van Melick, Yacov Reisman, Jan Krijgh, Frans M.J. Debruyne, Herjan J.T. Coelingh Bennink

Publikováno v: European Urology Open Science, Vol 45, Iss , Pp 59-67 (2022)

Background: Androgen deprivation therapy (ADT) for prostate cancer (PCa) is accompanied by side effects affecting health-related quality of life (HRQL). Objective: To assess the effects of the fetal estrogen estetrol (E4) on symptoms related to estro

Externí odkaz: https://doaj.org/article/5c791a225029429ea2c43b9b2ebebb83

Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer-A Systematic Review

Autor: Hilda A. de Barros, Isabeau van Beurden, Matteo Droghetti, Erica A. Wilthagen, Oktay Özman, Andries M. Bergman, Shafak Aluwini, R. Jeroen A. van Moorselaar, Maarten L. Donswijk, Pim J. van Leeuwen, Henk G. van der Poel

Publikováno v: de Barros, H A, van Beurden, I, Droghetti, M, Wilthagen, E A, Özman, O, Bergman, A M, Aluwini, S, van Moorselaar, R J A, Donswijk, M L, van Leeuwen, P J & van der Poel, H G 2023, ' Role of Local and/or Metastasis-directed Therapy in Patients with Hormone-sensitive M1a Prostate Cancer-A Systematic Review ', European Urology Oncology, vol. 6, no. 1, pp. 16-27 . https://doi.org/10.1016/j.euo.2022.10.002

CONTEXT: It remains unclear whether men with hormone-sensitive prostate cancer (PCa) metastasized to nonregional lymph nodes (M1a) benefit from prostate-directed therapy (PDT) and/or metastasis-directed therapy (MDT). OBJECTIVE: To systematically sum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f67e56e417f8adeadb489e03cfc006b6
https://doi.org/10.1016/j.euo.2022.10.002

PRDM10 directs FLCN expression in a novel disorder overlapping with Birt-Hogg-Dubé syndrome and familial lipomatosis

Autor: Irma van de Beek, Iris E Glykofridis, Jan C Oosterwijk, Peter C van den Akker, Gilles F H Diercks, Maria C Bolling, Quinten Waisfisz, Arjen R Mensenkamp, Jesper A Balk, Rob Zwart, Alex V Postma, Hanne E J Meijers-Heijboer, R Jeroen A van Moorselaar, Rob M F Wolthuis, Arjan C Houweling

Publikováno v: van de Beek, I, Glykofridis, I E, Oosterwijk, J C, van den Akker, P C, Diercks, G F H, Bolling, M C, Waisfisz, Q, Mensenkamp, A R, Balk, J A, Zwart, R, Postma, A V, Meijers-Heijboer, H E J, van Moorselaar, R J A, Wolthuis, R M F & Houweling, A C 2023, ' PRDM10 directs FLCN expression in a novel disorder overlapping with Birt-Hogg-Dubé syndrome and familial lipomatosis ', Human Molecular Genetics, vol. 32, no. 7, pp. 1223-1235 . https://doi.org/10.1093/hmg/ddac288
Human Molecular Genetics, 32, 1223-1235
Human Molecular Genetics, 32(7), 1223-1235. Oxford University Press
Human molecular genetics, 32(7), 1223-1235. Oxford University Press
Human Molecular Genetics, 32, 7, pp. 1223-1235

Contains fulltext : 291515.pdf (Publisher’s version ) (Open Access) Birt-Hogg-Dubé syndrome (BHD) is an autosomal dominant disorder characterized by fibrofolliculomas, pulmonary cysts, pneumothoraces and renal cell carcinomas. Here, we reveal a no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19bee29415900ea2982a28cc3469f7db
https://research.vumc.nl/en/publications/d755d70a-4c1f-4979-ab6b-f902c4942091

Bladder cancer detection in urine using DNA methylation markers

Autor: Anouk E. Hentschel, Irene J. Beijert, Judith Bosschieter, Paul C. Kauer, André N. Vis, Birgit I. Lissenberg-Witte, R. Jeroen A. van Moorselaar, Renske D. M. Steenbergen, Jakko A. Nieuwenhuijzen

Publikováno v: Clinical epigenetics, 14(1):19. Springer Verlag
Clinical Epigenetics
Hentschel, A E, Beijert, I J, Bosschieter, J, Kauer, P C, Vis, A N, Lissenberg-Witte, B I, van Moorselaar, R J A, Steenbergen, R D M & Nieuwenhuijzen, J A 2022, ' Bladder cancer detection in urine using DNA methylation markers : a technical and prospective preclinical validation ', Clinical epigenetics, vol. 14, no. 1, 19 . https://doi.org/10.1186/s13148-022-01240-8

Background The development of accurate urinary biomarkers for non-invasive and cost-effective detection of primary and recurrent bladder tumours is recognized as one of the major clinical needs in bladder cancer diagnostics. The purposes of this stud

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08afc32c6c55adb072bc925d8bf642fc
https://www.scopus.com/inward/record.uri?partnerID=HzOxMe3b&scp=85124231238&origin=inward