Zobrazeno 1 - 10
of 561
pro vyhledávání: '"R Jeffries"'
Autor:
Szi Kay Leung, Rosemary A. Bamford, Aaron R. Jeffries, Isabel Castanho, Barry Chioza, Christine S. Flaxman, Karen Moore, Emma L. Dempster, Joshua Harvey, Jonathan T. Brown, Zeshan Ahmed, Paul O’Neill, Sarah J. Richardson, Eilis Hannon, Jonathan Mill
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Increasing evidence suggests that alternative splicing plays an important role in Alzheimer’s disease (AD) pathology. We used long-read sequencing in combination with a novel bioinformatics tool (FICLE) to profile transcript diversity in t
Externí odkaz:
https://doaj.org/article/61f3ea0e8bfe4d4fbbcfd3346aaa8d89
Autor:
Benedikt Kirchebner, Kellen D. Traxel, Alexander E. Wilson-Heid, Eric S. Elton, Andrew J. Pascall, Jason R. Jeffries
Publikováno v:
Additive Manufacturing Letters, Vol 11, Iss , Pp 100259- (2024)
Molten metal jetting (MMJ) is an additive manufacturing (AM) method where droplets of molten metal are used to build parts. Like most AM technologies, MMJ is typically used to build stand-alone parts rather than add onto existing parts. However, the
Externí odkaz:
https://doaj.org/article/d3cee7d4215c45d4bbc31f592daa1d71
Publikováno v:
Additive Manufacturing Letters, Vol 11, Iss , Pp 100240- (2024)
Additive manufacturing (AM) of many traditional aluminum alloys is difficult due to hot cracking during cooling, which motivates investigating alternative AM methods that can mitigate this challenge. Here we demonstrate a new pneumatically driven mol
Externí odkaz:
https://doaj.org/article/ddb83afc0bf74ad3a61485e75f03a01f
Autor:
Ailsa MacCalman, Elisa De Franco, Alice Franklin, Christine S. Flaxman, Sarah J. Richardson, Kathryn Murrall, Joe Burrage, Barts Pancreas Tissue Bank (BPTB), Emma M. Walker, Noel G. Morgan, Andrew T. Hattersley, Emma L. Dempster, Eilis Hannon, Aaron R. Jeffries, Nick D. L. Owens, Jonathan Mill
Publikováno v:
BMC Genomics, Vol 25, Iss 1, Pp 1-18 (2024)
Abstract Development of the human pancreas requires the precise temporal control of gene expression via epigenetic mechanisms and the binding of key transcription factors. We quantified genome-wide patterns of DNA methylation in human fetal pancreati
Externí odkaz:
https://doaj.org/article/ea742da1a75a4ea5b89b8681cb5b5745
Autor:
Harry T. Child, George Airey, Daniel M. Maloney, Abby Parker, Jonathan Wild, Suzie McGinley, Nicholas Evens, Jonathan Porter, Kate Templeton, Steve Paterson, Ronny van Aerle, Matthew J. Wade, Aaron R. Jeffries, Irene Bassano
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
Externí odkaz:
https://doaj.org/article/0a7d722e52894ab2a2e42c7794ba5570
Autor:
Shayma Alathari, Andrew Joseph, Luis M. Bolaños, David J. Studholme, Aaron R. Jeffries, Patrick Appenteng, Kwaku A. Duodu, Eric B. Sawyerr, Richard Paley, Charles R. Tyler, Ben Temperton
Publikováno v:
PeerJ, Vol 12, p e17605 (2024)
Viral outbreaks are a constant threat to aquaculture, limiting production for better global food security. A lack of diagnostic testing and monitoring in resource-limited areas hinders the capacity to respond rapidly to disease outbreaks and to preve
Externí odkaz:
https://doaj.org/article/480340734c21432ebc874ecc5612ed3a
Autor:
Nihar Bhattacharyya, Niuzheng Chai, Nathaniel J Hafford-Tear, Amanda N Sadan, Anita Szabo, Christina Zarouchlioti, Jana Jedlickova, Szi Kay Leung, Tianyi Liao, Lubica Dudakova, Pavlina Skalicka, Mohit Parekh, Ismail Moghul, Aaron R Jeffries, Michael E Cheetham, Kirithika Muthusamy, Alison J Hardcastle, Nikolas Pontikos, Petra Liskova, Stephen J Tuft, Alice E Davidson
Publikováno v:
PLoS Genetics, Vol 20, Iss 5, p e1011230 (2024)
Fuchs endothelial corneal dystrophy (FECD) is an age-related cause of vision loss, and the most common repeat expansion-mediated disease in humans characterised to date. Up to 80% of European FECD cases have been attributed to expansion of a non-codi
Externí odkaz:
https://doaj.org/article/2483dcb3baf447028431d996808cd5cd
Autor:
Kristen Shelton, Gargi N. Deshpande, Gilson J. Sanchez, Jason R. Vogel, A. Caitlin Miller, Gabriel Florea, Erin R. Jeffries, Kara B. De Leόn, Bradley Stevenson, Katrin Gaardbo Kuhn
Publikováno v:
Microorganisms, Vol 12, Iss 10, p 2001 (2024)
During the COVID-19 pandemic, wastewater surveillance was used to monitor community transmission of SARS-CoV-2. As new genetic variants emerged, the need for timely identification of these variants in wastewater became an important focus. In response
Externí odkaz:
https://doaj.org/article/9248976dbad8488698ce98dcfe3916cd
Autor:
Kellen D. Traxel, Eric S. Elton, Amelia M. Petersen, Chinthaka M. Silva, Aurélien Perron, Jason R. Jeffries, Andrew J. Pascall
Publikováno v:
Materials & Design, Vol 237, Iss , Pp 112544- (2024)
Control over the microstructure and properties of alloys produced via additive manufacturing (AM) is a key barrier that limits widespread industrial adoption. Herein we demonstrate that liquid metal jetting (LMJ), an emerging metal-AM technique, can
Externí odkaz:
https://doaj.org/article/a1deb8f678ec4942b30d3a61bb71026c
Autor:
Harry T. Child, George Airey, Daniel M. Maloney, Abby Parker, Jonathan Wild, Suzie McGinley, Nicholas Evens, Jonathan Porter, Kate Templeton, Steve Paterson, Ronny van Aerle, Matthew J. Wade, Aaron R. Jeffries, Irene Bassano
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTWastewater-based epidemiology is a powerful tool for monitoring the emergence and spread of viral pathogens at the population scale. Typical polymerase chain reaction (PCR)-based methods of quantitative and genomic monitoring of viruses in wa
Externí odkaz:
https://doaj.org/article/7ff7e5564a6342bfa615a2ba92d6299e