Zobrazeno 1 - 2
of 2
pro vyhledávání: '"R Jefferey Karnes"'
Autor:
Neha Singh, Varune R. Ramnarine, Jin H. Song, Ritu Pandey, Sathish K. R. Padi, Mannan Nouri, Virginie Olive, Maxim Kobelev, Koichi Okumura, David McCarthy, Michelle M. Hanna, Piali Mukherjee, Belinda Sun, Benjamin R. Lee, J. Brandon Parker, Debabrata Chakravarti, Noel A. Warfel, Muhan Zhou, Jeremiah J. Bearss, Ewan A. Gibb, Mohammed Alshalalfa, R. Jefferey Karnes, Eric J. Small, Rahul Aggarwal, Felix Feng, Yuzhuo Wang, Ralph Buttyan, Amina Zoubeidi, Mark Rubin, Martin Gleave, Frank J. Slack, Elai Davicioni, Himisha Beltran, Colin Collins, Andrew S. Kraft
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-20 (2021)
Elevated expression of long noncoding RNA H19 is seen in clinical samples of neuroendocrine prostate cancer (PCa). Here the authors show H19 promotes plasticity from luminal to neuroendocrine by epigenetic reprogramming.
Externí odkaz:
https://doaj.org/article/fe3ffb322dcb47a8b750da286a3e5ab2
Autor:
Mohammed Alshalalfa, Harrison Tsai, Sonal Brahmbhatt, Nicholas Erho, Robert Shukin, Colin Collins, Himisha Beltran, R Jefferey Karnes, Fan Mo, Noushin Nabavi, Yuzhuo Wang, Maxim Kobelev, Dong Lin, Tamara L. Lotan, Mannan Nouri, Alexander R. Gawronski, Amina Zoubeidi, Elai Davicioni, Mark A. Rubin, Cenk Sahinalp, Mandeep Takhar, Varune Rohan Ramnarine, Stanislav Volik, Martin E. Gleave, Alexander W. Wyatt
Publikováno v:
GigaScience
Background Treatment-induced neuroendocrine prostate cancer (tNEPC) is an aggressive variant of late-stage metastatic castrate-resistant prostate cancer that commonly arises through neuroendocrine transdifferentiation (NEtD). Treatment options are li