Zobrazeno 1 - 10
of 27
pro vyhledávání: '"R J Winquist"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 291(2)
We report on the development of a method for repeated monitoring of mucosal permeability that allows assessment of the severity of colitis and evaluation of treatment efficacy in HLA-B27 transgenic rats. We determined the extent to which intestinal p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9f1aee4d17f033e45c32f6492c77efe0
https://pubmed.ncbi.nlm.nih.gov/10525115
https://pubmed.ncbi.nlm.nih.gov/10525115
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 287(2)
We investigated the contractile effects of both activated and unactivated polymorphonuclear leukocytes (PMNs) on human vascular tissue to characterize the influence of human PMNs on vascular tone. PMNs were added either unactivated or after f-met-leu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f33bc0b5425cf22701d7c5d3116f4d59
https://pubmed.ncbi.nlm.nih.gov/9808691
https://pubmed.ncbi.nlm.nih.gov/9808691
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 272(1)
NG-nitro-L-arginine methyl ester (L-NAME) has been reported to have variable effects on the vasodilator response to acetylcholine (ACh) and bradykinin (BK) in vivo. Whether administration of L-NAME affects mean arterial pressure (MAP) or heart rate (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::768e2c5410c8e0a14be5d7a4d1396ced
https://pubmed.ncbi.nlm.nih.gov/7529307
https://pubmed.ncbi.nlm.nih.gov/7529307
Effects of losartan (DuP753) and enalaprilat on the mean arterial pressure response to phenylephrine
Autor:
J B, Madwed, R J, Winquist
Publikováno v:
Journal of hypertension. 12(2)
We have found that low-dose infusion of angiotensin II (Ang II) selectively potentiates the mean arterial pressure (MAP) response to phenylephrine in pentobarbital-anesthetized rabbits.To examine whether endogenous Ang II levels in normotensive rabbi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1136d2466c10658c4a8101342a8a7a5
https://pubmed.ncbi.nlm.nih.gov/8021467
https://pubmed.ncbi.nlm.nih.gov/8021467
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 263(3)
The renal vascular effects of serotonin (5-HT) in vivo vary among preparations, which may reflect that this autacoid can modulate the vascular response to certain spasmogens. We investigated this phenomenon in the isolated rabbit kidney perfused unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::480a3171f6d26ba5edc9bc8f243f5f40
https://pubmed.ncbi.nlm.nih.gov/1469648
https://pubmed.ncbi.nlm.nih.gov/1469648
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(3)
Experiments were performed to investigate the vascular reactivity in both large and resistance artery preparations from an animal model of septic shock. New Zealand White rabbits were injected with a priming dose of Escherichia coli lipopolysaccharid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c703f1c28d99fda5503aa4669fd169c
https://pubmed.ncbi.nlm.nih.gov/1602401
https://pubmed.ncbi.nlm.nih.gov/1602401
Autor:
M L, Garcia, V F, King, J L, Shevell, R S, Slaughter, G, Suarez-Kurtz, R J, Winquist, G J, Kaczorowski
Publikováno v:
The Journal of biological chemistry. 265(7)
Three structural classes of commonly used amiloride analogs, molecules derivatized at the terminal guanidino-nitrogen, the five-position pyrazinoyl-nitrogen, or di-substituted at both of these positions, inhibit binding of the L-type Ca2+ channel mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::399325dc6746503fca9fd334edd3dfd7
https://pubmed.ncbi.nlm.nih.gov/2154487
https://pubmed.ncbi.nlm.nih.gov/2154487
Autor:
L W, Schaffer, T W, Schorn, R J, Winquist, J F, Strouse, L, Payne, P K, Chakravarty, S E, de Laszlo, J, tenBroeke, D F, Veber, W J, Greenlee
Publikováno v:
Journal of hypertension. 8(3)
In order to investigate the hypotensive mechanisms of action of peptide renin inhibitors, blood pressure responses to five renin inhibitors were compared with those to the angiotensin converting enzyme inhibitor, enalaprilat, in conscious African gre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::28090731ee7990262391c08b15a32a89
https://pubmed.ncbi.nlm.nih.gov/2159506
https://pubmed.ncbi.nlm.nih.gov/2159506
Publikováno v:
Circulation Research. 51:769-776
The large arteries at the base of the brain in the pig were studied in vitro for their responsiveness to neurogenic and humoral stimuli. Helical strips of these cerebral vessels tonically contracted consistently following application of resting force
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a47149a16b650694793a83b537238dd
https://doi.org/10.1161/01.res.51.6.769
https://doi.org/10.1161/01.res.51.6.769
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 241:H211-H216
The effects of lead on vascular responsiveness were examined in rats. Adult rats, which had received levels of lead acetate in their drinking water to produce blood levels similar to those seen in some urban human populations, consistently had higher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea717873c6c05377e57a8a44d85cb82d
https://doi.org/10.1152/ajpheart.1981.241.2.h211
https://doi.org/10.1152/ajpheart.1981.241.2.h211