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IFN-gamma potentiates the accumulation of diacylglycerol in murine macrophages

Autor: R J Sebaldt, V Prpic, P W Hollenbach, D O Adams, R J Uhing

Publikováno v: The Journal of Immunology. 145:684-689

Activation of mononuclear phagocytes for a variety of functional responses is potentiated by prior exposure to IFN-gamma. Inasmuch as protein kinase C has been suggested to mediate several of these responses, we have examined the effects of IFN-gamma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e3dec09a8f90f950a5f3430fcb7b23e
https://doi.org/10.4049/jimmunol.145.2.684

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36 month intermittent cyclical etidronate treatment in patients with established corticosteroid induced osteoporosis

Autor: R J, Sebaldt, G, Ioannidis, J D, Adachi, W G, Bensen, F, Bianchi, A, Cividino, M, Gordon, E, Kaminska, T, Scocchia, A, Petrie, G F, Stephenson, C H, Goldsmith

Publikováno v: The Journal of rheumatology. 26(7)

To determine the longterm safety and efficacy of etidronate therapy in patients in whom corticosteroid induced bone loss has already occurred.We performed a 36 month observational cohort study in which all data were obtained from Canadian Database of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d4fe2af5e661ae36c2f3f94f0bb2801f
https://pubmed.ncbi.nlm.nih.gov/10405943

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Fluoride therapy in prevention of rheumatoid arthritis induced bone loss

Autor: J D, Adachi, M J, Bell, W G, Bensen, F, Bianchi, A, Cividino, R J, Sebaldt, M, Gordon, G, Ioannidis, C, Goldsmith

Publikováno v: The Journal of rheumatology. 24(12)

To determine the efficacy of sodium fluoride (40 mg/day) in preventing rheumatoid arthritis (RA) induced bone loss, which may lead to osteoporosis.We conducted an 18 month, randomized, double blind, placebo controlled trial in 38 patients with RA. Th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ba189898b92e14d8017c7703b22642f8
https://pubmed.ncbi.nlm.nih.gov/9415633

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Diradylglycerol formation is altered by n-3 highly unsaturated fatty acids, with differences between eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids

Autor: R J, Sebaldt, P, Marignani

Publikováno v: Advances in experimental medicine and biology.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::825df70c72250baaab6c043a71eb39d2
https://pubmed.ncbi.nlm.nih.gov/9547650

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The formation of diradylglycerol molecular species in murine peritoneal macrophages varies dose-dependently with dietary purified eicosapentaenoic and docosahexaenoic ethyl esters

Autor: P A, Marignani, R J, Sebaldt

Publikováno v: The Journal of nutrition. 126(11)

Substantial effects of dietary fish oil-derived fatty acid ethyl esters on the metabolism of diradylglycerol (DG) have recently been described. We undertook to isolate the separate effects of (n-3) eicosapentaenoic acid (EPA) and (n-3) docosahexaenoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::90bc71b441b38d2474d6385eaf9f6bfb
https://pubmed.ncbi.nlm.nih.gov/8914943

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Vitamin D and calcium in the prevention of corticosteroid induced osteoporosis: a 3 year followup

Autor: J D, Adachi, W G, Bensen, F, Bianchi, A, Cividino, S, Pillersdorf, R J, Sebaldt, P, Tugwell, M, Gordon, M, Steele, C, Webber, C H, Goldsmith

Publikováno v: The Journal of rheumatology. 23(6)

To determine the efficacy and safety of vitamin D 50,000 units/week and calcium 1,000 mg/day in the prevention of corticosteroid induced osteoporosis.A minimized double blind, placebo controlled trial in corticosteroid treated subjects in a tertiary

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2777c9762ca3a2bd0b9612e69c7b3888
https://pubmed.ncbi.nlm.nih.gov/9035007

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Evidence based health informatics: an overview of the Health Information Research Unit at McMaster University

Autor: R B, Haynes, R S, Hayward, A R, Jadad, R J, Sebaldt

Publikováno v: Leadership in health services = Leadership dans les services de sante. 5(3)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1c01c795ad5bf2c3700146536cefe33e
https://pubmed.ncbi.nlm.nih.gov/10158411

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Formation of second messenger diradylglycerol in murine peritoneal macrophages is altered after in vivo (n-3) polyunsaturated fatty acid supplementation

Autor: P A, Marignani, R J, Sebaldt

Publikováno v: The Journal of nutrition. 125(12)

The consequences of macrophage membrane incorporation of (n-3) polyunsaturated fatty acids (PUFA) on diradylglycerol (DG) formation and phospholipase-mediated signal transduction in vivo remain largely unknown. Three-to four-week-old C57BL/6 mice wer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::95f644b0a8ec54a9e8a89d8e5393b2e3
https://pubmed.ncbi.nlm.nih.gov/7500181

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