Zobrazeno 1 - 10
of 20
pro vyhledávání: '"R J Ruane"'
Publikováno v:
Journal of Chromatography A. 553:497-501
The preparation of a two-phase “Pirkle” modified amino-bonded thin-layer chromatography (TLC) plate for enantiomer separation is described. The plate was prepared by partially immersing a commercially prepared aminopropyl high-performance TLC pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a4d9688d430e08c3ff456ea11e21b5bc
https://doi.org/10.1016/s0021-9673(01)88521-6
https://doi.org/10.1016/s0021-9673(01)88521-6
Publikováno v:
Xenobiotica. 21:1243-1256
1. Bolus i.v. doses of 14C-propofol (7-10 mg/kg) to rat, dog and rabbit, or an infusion dose (0.47 mg/kg per min for 6 h) to dog were eliminated primarily in urine (60-95% dose); faecal elimination (13-31%) occurred for rat and dog, but was minimal (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01183538f7e92d5e469e8db55a6972cb
https://doi.org/10.3109/00498259109043199
https://doi.org/10.3109/00498259109043199
Publikováno v:
Xenobiotica. 21:1325-1335
1. Bolus i.v. doses of 14C-propofol (9 mg/kg) were administered to female rats for measurement of tissue levels of total 14C and propofol from 2 min to 24 h post-dose; whole-body autoradiography was studied at 6 min, 2 h and 24 h post-dose, and also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a97f75ebeaf8309e76faaebba32e697
https://doi.org/10.3109/00498259109043207
https://doi.org/10.3109/00498259109043207
Publikováno v:
Applications of Supercritical Fluids in Industrial Analysis ISBN: 9789401049511
Over the last decade high performance liquid chromatography (HPLC) has become firmly established as the pre-eminent separation technique for the chromatography and analysis of drugs and pharmaceuticals. Clearly it is against this background that the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::776c5f4a3da76b04b9c4b8f5ad1db511
https://doi.org/10.1007/978-94-011-2146-0_4
https://doi.org/10.1007/978-94-011-2146-0_4
Publikováno v:
Xenobiotica; the fate of foreign compounds in biological systems. 22(11)
1. Propofol glucuronide (PG) is the major human metabolite of the i.v. anaesthetic propofol, 2,6-diisopropylphenol. 2. Bolus i.v. doses of 14C-PG (1 mg/kg) to rat and dog were eliminated in urine (40 and 66% respectively) and faeces (48 and 19%); 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05cb73e6940e1871876367675f47b00
https://pubmed.ncbi.nlm.nih.gov/1492419
https://pubmed.ncbi.nlm.nih.gov/1492419
Publikováno v:
Recent Advances in Chiral Separations ISBN: 9781468482843
Recent progress in thin-layer chromatography (TLC) as a means for the separation of enantiomers is reviewed. The areas discussed include separations using ligand exchange, ion-pair, cyclodextrin and “Pirkle”-based chiral TLC systems. The use of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::218ca8e8ff379fa72fd29fe74d4c8c7f
https://doi.org/10.1007/978-1-4684-8282-9_21
https://doi.org/10.1007/978-1-4684-8282-9_21
Autor:
C. J. Keattch, J. C. Lindon, R. A. Young, John F. Watts, R. Blackburn, P. T. McGrail, A. Dyer, E. J. Newman, B. Caddy, R. J. Ruane, Neil I. Ward, A. H. B. Deas
Publikováno v:
The Analyst. 118:141N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa0d5171d1b15458513165ceba7f2645
https://doi.org/10.1039/an993180141n
https://doi.org/10.1039/an993180141n
Autor:
Terry M. Jefferies, Alan G. Howard, R. L. Tranter, D. V. MaCalley, A. D. Woolfson, Julian Tyson, R. J. Ruane, P. S. Belton
Publikováno v:
The Analyst. 116:1197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0228ec31e2c24e52769d8da85774026d
https://doi.org/10.1039/an9911601197
https://doi.org/10.1039/an9911601197
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 1:113-124
The metabolism of a new (β-adrenoceptor blocking agent, bufuralol, 7-ethyl-α[(tertiary butylamino)-methyl]-2-benzo-furan methanol. HC1, was studied in rat, dog and man. After oral administration of the labelled drug, 34 % of dose was eliminated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5f25a57aaa73783728138f34533555e
https://doi.org/10.1007/bf03189265
https://doi.org/10.1007/bf03189265
Publikováno v:
Water Science and Technology. 15:149-153
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25a14582966f2a65c2b8ad8ab50a9a2
https://doi.org/10.2166/wst.1983.0082
https://doi.org/10.2166/wst.1983.0082