Zobrazeno 1 - 10
of 14
pro vyhledávání: '"R J Pease"'
Publikováno v:
Journal of Lipid Research, Vol 37, Iss 10, Pp 2215-2231 (1996)
We have investigated the hypothesis that apolipoprotein B undergoes a regulated process of translocation into the endoplasmic reticulum (ER) which causes the protein to adopt a transmembrane configuration. Protein segments representing the complete c
Externí odkaz:
https://doaj.org/article/c1e8c02c78b9440489c152c9f583623e
Publikováno v:
Journal of Biological Chemistry. 269:21951-21954
Apolipoprotein (apo) B is an obligatory component of triglyceride-rich lipoproteins. In the rare autosomal recessive disorder abetalipoproteinemia (ABL), no triglyceride-rich lipoproteins are secreted. Mutations in the gene encoding the 97-kDa subuni
Publikováno v:
European Journal of Immunology
Recent reports have shown that both exogenous and endogenous mouse mammary tumor viruses (MMTV) can encode superantigens. Transfection and transgenic studies have identified the open reading frame (ORF) present in the 3′ long terminal repeat (LTR)
Publikováno v:
Biochemistry. 30:5616-5621
Apolipoprotein B has an obligatory role in the production of chylomicrons, VLDL, and LDL. Familial hypobetalipoproteinemia is a codominant disorder characterized by reduced levels of apo B containing lipoproteins in plasma. We have previously describ
Autor:
G C Chen, Clive R. Pullinger, J W Schilling, P Hass, J Scott, Steven T. Kunitake, Saiyong Zhu, R J Pease, John P. Kane, Stephen G. Young
Publikováno v:
Journal of Biological Chemistry. 265:20739-20746
The low density lipoproteins (LDL) from patients with Tangier disease are enriched in triglycerides, 27% of LDL mass versus 7% for normal LDL. To study whether this unique LDL core lipid composition affects the surface disposition of apolipoprotein (
Publikováno v:
Biochemical Society transactions. 29(Pt 2)
Liver microsomes contain two carnitine acyltransferase activities. One of these has properties closely corresponding to those of 88 kDa mitochondrial carnitine palmitoyltransferase-1 (CPT-1). Antisera against CPT-1 cross-react with an 88 kDa microsom
Publikováno v:
The Biochemical journal. 341
Clones of HepG2 cells were selected that stably express the cDNA for hormone-sensitive lipase (HSL). When cells were cultured in the presence of labelled extracellular oleate, accumulation of labelled fatty acid as cellular triacylglycerol (TAG) was
Microsomal triglyceride transfer protein (MTP) is a heterodimeric protein consisting of a unique 97 kDa subunit and protein disulphide isomerase, that mediates the transfer of lipid between membranes and nascent lipoproteins. Mutations in the gene en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86fa3700344b545f4b139b96fc943446
https://europepmc.org/articles/PMC1135847/
https://europepmc.org/articles/PMC1135847/
Publikováno v:
The Journal of biological chemistry. 267(22)
Physiological concentrations of oleate stimulate apolipoprotein (apo) B-containing lipoprotein secretion from HepG2 cells without increasing apoB mRNA levels. The purpose of this study was to determine whether oleate acts by increasing translation of
Autor:
R J, Pease, R W, Milne, W K, Jessup, A, Law, P, Provost, J C, Fruchart, R T, Dean, Y L, Marcel, J, Scott
Publikováno v:
The Journal of biological chemistry. 265(1)
Bacterial expression of apolipoprotein (apo) B cDNA constructs has been used to map a series of monoclonal antibodies (mAbs) to apoB by immunoblotting. In some cases assignments have been confirmed and refined by (i) semipurification of expressed pro