Zobrazeno 1 - 10
of 31
pro vyhledávání: '"R J Nickles"'
Autor:
H F, Valdovinos, R, Hernandez, S, Graves, P A, Ellison, T E, Barnhart, C P, Theuer, J W, Engle, W, Cai, R J, Nickles
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 130
This work presents the production with a cyclotron of the positron emitter 55Co via the 54Fe(d,n) and 58Ni(p,α) reactions and the Auger electron emitter 58mCo via the 57Fe(d,n) reaction after high current (40 μA p and 60 μA d) irradiation on elect
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 95
Significant interest in 44Sc as a radioactive synthon to label small molecules for positron emission tomography (PET) imaging has been recently observed. Despite the efforts of several research groups, the ideal 44Sc production and separation method
Autor:
James E. Holden, R. J. Nickles, C. K. Stone, C. Monge, Campbell M. Clark, C. Stanley, W. D. Brown, Peter W. Hochachka
Publikováno v:
Journal of Applied Physiology. 81:1355-1361
The brain of hypoxia-tolerant vertebrates is known to survive extreme oxygen limitation at least in part because of very low rats of ATP utilization and ATP production. To asses whether similar adaptations are involved in healthy humans during hypoxi
Autor:
D, Murali, T E, Barnhart, N T, Vandehey, B T, Christian, R J, Nickles, A K, Converse, J A, Larson, J E, Holden, M L, Schneider, O T, Dejesus
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 72
A simple synthesis of the dopamine transporter ligand [(18)F]FECNT with high radiochemical yield and short synthesis time, suitable for routine production is reported. Reaction of 2β-carbomethoxy-3β-(4-chlorophenyl)nortropane with [(18)F]2-fluoroet
Autor:
R J, Nickles, M A, Avila-Rodriguez, J A, Nye, E N, Houser, R G, Selwyn, M J, Schueller, B T, Christian, M, Jensen
Publikováno v:
The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 52(2)
Over a hundred proton-induced reactions have been studied at the University of Wisconsin Medical Physics department since the installation of the first CTI RDS 112 in 1985. The focus has been to measure thick target yields at 11 MeV, in an effort to
Autor:
T E, Barnhart, A K, Converse, K A, Dabbs, M J, Schueller, C K, Stone, R J, Nickles, A D, Roberts
Publikováno v:
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. 62(4)
Production of 17F (t1/2=65 s) in the form of [17F] F2 has been achieved using both the 20Ne(p,alpha)17F and 16O(d,n)17F reactions with 11 MeV protons and 6 MeV deuterons, respectively. Yields have proven suitable for subsequent radiosynthesis of the
Publikováno v:
AIP Conference Proceedings.
A gridded‐niobium target was constructed for the improvement of routine [18F]‐fluorine production from 18O‐enriched water on a CTI RDS 112 cyclotron. Niobium was chosen for its inertness and excellent thermal properties. The target volume consi
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 42(1)
Understanding the metabolic consequences of heart failure is important in evaluating potential mechanisms for disease progression and assessing targets for therapies designed to improve myocardial metabolism in patients with heart failure. PET is uni
Publikováno v:
Synapse (New York, N.Y.). 39(1)
The effect of aging on aromatic L-amino acid decarboxylase (AAAD) activity in rhesus monkey striatum was assessed in vivo using PET imaging. Two analogs of L-DOPA, 6-fluoro-m-tyrosine (FMT) and 6-fluoro-L-DOPA (FDOPA), were used to image rhesus monke
Publikováno v:
Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 39(11)
Copper-62-pyruvaldehyde bis(N4-methyl)thiosemicarbazone (PTSM) has been proposed as a generator-produced radiopharmaceutical for perfusion imaging using PET. Several clinical studies have demonstrated the ability of 62Cu-PTSM to quantitate myocardial