Zobrazeno 1 - 10
of 71
pro vyhledávání: '"R J Looney"'
Publikováno v:
JAAD Case Reports
JAAD Case Reports, Vol 15, Iss, Pp 33-35 (2021)
JAAD Case Reports, Vol 15, Iss, Pp 33-35 (2021)
Despite a common CD4+ T-cell precursor, helper T (Th) 1 and 2 lymphocytes affect different immunologic responses, including cellular and humoral pathways, respectively. Th1 cells stimulate the activation of type 1 macrophages, IgG/immunoglobulin M pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ba2c222d1c79372d89865fb68dd723
https://doi.org/10.1016/j.jdcr.2021.07.003
https://doi.org/10.1016/j.jdcr.2021.07.003
Publikováno v:
Lupus. 29:1040-1049
Background Bone marrow mesenchymal stem cells are multipotent adult stem cells that can differentiate into osteoblasts, adipocytes, and chondrocytes. Our recently published data demonstrate that systemic lupus erythematous bone marrow mesenchymal ste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2dcbd27928338c3646eda93e0ef6c546
https://doi.org/10.1177/0961203320930088
https://doi.org/10.1177/0961203320930088
Autor:
Liliana Michelle Gomez Mendez, Brad H. Rovin, Maria Dall'Era, Leonard Dragone, Matthew D Cascino, R J Looney, Paul Brunetta, Paul Brakeman, Tamiko R. Katsumoto, J Garg
Publikováno v:
Clinical Journal of the American Society of Nephrology. 13:1502-1509
Background and objectives Incomplete peripheral blood B cell depletion after rituximab in lupus nephritis might correlate with inability to reduce tubulointerstitial lymphoid aggregates in the kidney, which together could be responsible for inadequat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d56f1d55693a1027923067135603530b
https://doi.org/10.2215/cjn.01070118
https://doi.org/10.2215/cjn.01070118
Publikováno v:
Annals of allergy, asthmaimmunology : official publication of the American College of Allergy, Asthma,Immunology. 124(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb93d6d3dad68e45d1e2776a469a352b
https://pubmed.ncbi.nlm.nih.gov/31923545
https://pubmed.ncbi.nlm.nih.gov/31923545
Autor:
Jennifer H. Anolik, Andrew McDavid, Mary J. O'Connell, Jane L. Liesveld, R J Looney, Lin Gao, Maria Allen
Publikováno v:
Cytokine. 132
Background We have previously shown that SLE BMSC have decreased proliferation, increased ROS, increased DNA damage and repair (DDR), a senescence associated secretory phenotype, and increased senescence-associated β-galactosidase. We have also show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb745b45c3ca94d797654ccc36117cbd
https://pubmed.ncbi.nlm.nih.gov/31153744
https://pubmed.ncbi.nlm.nih.gov/31153744
Publikováno v:
Innate Immunity.
Background We have previously shown that SLE BMSCs have a pro-inflammatory mediated by a MAVS and IFNβ feedback loop. Compared to healthy controls, SLE BMSCs produced increased amounts of IFNβ and had increased mRNA for several genes induced relati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::852edf61821e3888cae3bc0e5bab5c9e
https://doi.org/10.1136/lupus-2018-lsm.103
https://doi.org/10.1136/lupus-2018-lsm.103
Publikováno v:
Poster session 7: New drugs and trageted therapy.
Bone marrow mesenchymal stromal cells (BM-MSCs) are multipotent stem cells that can differentiate into chondrocytes, osteoblasts and adipocytes. SLE has been implicated as a stem cell disorder with impaired immunomodulatory function of SLE BM-MSCs an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::635e8b51d98cfb481d2e33276ac9a71e
https://doi.org/10.1136/lupus-2018-abstract.173
https://doi.org/10.1136/lupus-2018-abstract.173
Autor:
Antti Seppo, Maria Allen, Kirsi M. Jarvinen-Seppo, Sade Fridy, Richard W. Stahlhut, James J. Kobie, Camille A. Martina, Jonathan Phillips, R J Looney, Alexander F. Rosenberg
Publikováno v:
Journal of Allergy and Clinical Immunology. 143:AB87
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b4a0be85bd71aa096da0992cc13b2f7
https://doi.org/10.1016/j.jaci.2018.12.268
https://doi.org/10.1016/j.jaci.2018.12.268
Publikováno v:
Lupus. 13:381-390
Systemic lupus erythematosus (SLE) is a complex disease characterizedby numerous autoantibodies and clinical involvement in multiple organ systems. Autoantibodies are usually present in serum for years before the onset of clinical disease. Autoimmuni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9244e6ad00b099bd6c00bab160ee344
https://doi.org/10.1191/0961203304lu1031oa
https://doi.org/10.1191/0961203304lu1031oa
Publikováno v:
The Journal of Infectious Diseases. 185:682-685
In vitro cytokine production in response to respiratory syncytial virus (RSV) and influenza infections was investigated in 11 "young" (mean age, 31 years) and "older" (mean age, 75 years) healthy volunteers by use of interferon (IFN)-gamma ELISPOT an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdae20dd59d8b6800c004bff09a8823c
https://doi.org/10.1086/339008
https://doi.org/10.1086/339008