Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R J Landers"'
Publikováno v:
The Journal of Pathology. 192:150-158
Angiogenesis is essential to the growth and metastasis of solid tumours. Vascular endothelial growth factor (VEGF) is a potent pro-angiogenic cytokine that is overexpressed in malignant tumours such as invasive carcinoma of the breast. The low oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46ccf9aa71949ed65b796d3e7d2e1323
https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path687>3.0.co
https://doi.org/10.1002/1096-9896(2000)9999:9999<::aid-path687>3.0.co
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
Angiogenesis is an essential requirement for tumour growth and metastasis and is regulated by a complex network of factors produced by both stromal cells and neoplastic cells within solid tumours. The cytokine tumour necrosis factor alpha (TNF-alpha)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7e0455a55c3a131f559ecadeeb5de29
https://doi.org/10.1038/bjc.1998.373
https://doi.org/10.1038/bjc.1998.373
Autor:
F A Lewis, R J Landers, Michael J. Crowley, G Browne, A M Pollock, I Healy, John J. O'Leary, M I Johnson, A Andrew, John Street
Publikováno v:
Journal of Clinical Pathology. 47:933-938
AIMS--To investigate the feasibility of using fixed cells with the polymerase chain reaction (PCR) in situ hybridisation and to investigate possible reasons for reaction failure. METHODS--Fixed SiHa and CaSki cells were used in an experimental model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6cefd2b0a815de5d5eed1c4651f170
https://doi.org/10.1136/jcp.47.10.933
https://doi.org/10.1136/jcp.47.10.933
Autor:
J. J. O'Leary, G. Browne, R. J. Landers, M. Crowley, I. Bailey Healy, J. T. Street, A. M. Pollock, J. Murphy, M. I. Johnson, F. A. Lewis, O. Mohamdee, C. Cullinane, C. T. Doyle
Publikováno v:
The Histochemical Journal. 26:337-346
Conventional solution-phase polymerase chain reaction (PCR) and in situ PCR/PCR in situ hybridization are powerful tools for retrospective analysis of fixed paraffin wax-embedded material. Amplification failure using these techniques is now encounter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e78e1c55f5790d9ee242f77e260f974
https://doi.org/10.1007/bf00157767
https://doi.org/10.1007/bf00157767
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 3:78-86
In 1985, Mullis discovered an exponentially increasing amplification system for nucleic acids, which became known as the polymerase chain reaction (PCR). This method permits the selective in vitro amplification of a particular DNA region by mimicking
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4d60dde378d542c43f9264412269cb25
https://doi.org/10.1111/j.1468-3083.1994.tb00077.x
https://doi.org/10.1111/j.1468-3083.1994.tb00077.x
Publikováno v:
The Journal of pathology. 192(2)
Angiogenesis is essential to the growth and metastasis of solid tumours. Vascular endothelial growth factor (VEGF) is a potent pro-angiogenic cytokine that is overexpressed in malignant tumours such as invasive carcinoma of the breast. The low oxygen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a57170337fb135426a293fded4fdbf19
https://pubmed.ncbi.nlm.nih.gov/11004690
https://pubmed.ncbi.nlm.nih.gov/11004690
Publikováno v:
British Journal of Cancer
Necrosis is a common feature of invasive carcinoma of the breast and is caused by chronic ischaemia leading to infarction. Although necrosis was previously assumed to be due to a generally poor blood supply in the tumour, in this study we show that i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e5b8df344756e877da427650f0759d2
Publikováno v:
Journal of clinical pathology. 51(8)
AIM: To examine the prevalence of genital type human papilloma virus (HPV) and mutations at codons 12, 13, and 61 in H, Ki, and N-ras in CIN III and early invasive squamous cell carcinomas of the cervix. METHODS: Prevalence of HPV was examined in 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1b1c63bec18bca80a6d5d6286d59fd
https://pubmed.ncbi.nlm.nih.gov/9828814
https://pubmed.ncbi.nlm.nih.gov/9828814
AIMS: To examine human papillomavirus (HPV) positive and negative squamous cell carcinomas of the cervix for structural alterations in exon 1 c-myc; and to investigate the expression pattern of p62, the protein product of c-myc. MATERIAL: Archival pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2047089cb514f14b8fc0c61229c5bd56
https://europepmc.org/articles/PMC500312/
https://europepmc.org/articles/PMC500312/
Autor:
C Cullinane, C T Doyle, I Healy, John J. O'Leary, Michael J. Crowley, W F Kealy, P Kelehan, R J Landers, J Hogan
AIMS: To examine the prevalence of human papillomavirus (HPV) and Epstein-Barr virus (EBV) in low grade glandular intraepithelial lesions of the cervix, adenocarcinoma with high grade glandular intraepithelial lesions combined, and adenocarcinomas; a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8314d3cdd8af98caaaa4b6f2435cbcac
https://europepmc.org/articles/PMC500313/
https://europepmc.org/articles/PMC500313/