Zobrazeno 1 - 8
of 8
pro vyhledávání: '"R J Gulakowski"'
Autor:
T C, McKee, J H, Cardellina, R, Riccio, M V, D'Auria, M, Iorizzi, L, Minale, R A, Moran, R J, Gulakowski, J B, McMahon, R W, Buckheit
Publikováno v:
Journal of Medicinal Chemistry. 37:793-797
A total of 22 sulfated sterols isolated from marine sponges, ophiuroids (brittle stars), and asteroids (sea stars) were comparatively evaluated for their antiviral activity against HIV-1 and HIV-2. In general, sterols with sulfate groups at position
Autor:
R Pedemonte, William Decker, V L Narayanan, Owen S. Weislow, J. B. McMahon, Robert W. Buckheit, R J Schultz, F W Wassmundt, R J Gulakowski, D. J. Clanton
Publikováno v:
Antimicrobial Agents and Chemotherapy. 37:754-760
A series of variously substituted diarylsulfones and related derivatives were found to prevent human immunodeficiency virus type 1 (HIV-1) replication and HIV-1-induced cell killing in vitro. One of the more potent derivatives, 2-nitrophenyl phenyl s
Autor:
K R, Gustafson, J H, Cardellina, J B, McMahon, R J, Gulakowski, J, Ishitoya, Z, Szallasi, N E, Lewin, P M, Blumberg, O S, Weislow, J A, Beutler
Publikováno v:
Journal of Medicinal Chemistry. 35:1978-1986
Extracts of Homalanthus nutans, a plant used in Samoan herbal medicine, exhibited potent activity in an in vitro, tetrazolium-based assay which detects the inhibition of the cytopathic effects of human immunodeficiency virus (HIV-1). The active const
Autor:
B R, O'Keefe, T, Erim, J A, Beutler, J H, Cardellina, R J, Gulakowski, B L, Krepps, J B, McMahon, R C, Sowder, D G, Johnson, R W, Buckheit, S, Halliday, M R, Boyd
Publikováno v:
FEBS letters. 431(1)
Aqueous extracts of the New Zealand sponge Adocia sp. (Haplosclerida) displayed potent anticytopathic activity in CEM-SS cells infected with HIV-1. Protein fractions of the extract bound both to the viral coat protein gp120 and to the cellular recept
Autor:
R J Gulakowski, P L Nara, J H Cardellina, J B McMahon, Robert W. Buckheit, Robert H. Shoemaker, R C Sowder, Barry R. O'Keefe, C M Laurencot, M I Rivera, Michael R. Boyd, Kirk R. Gustafson, M J Currens, L Wu, L E Henderson, Lewis K. Pannell, Toshiyuki Mori
We have isolated and sequenced a novel 11-kDa virucidal protein, named cyanovirin-N (CV-N), from cultures of the cyanobacterium (blue-green alga) Nostoc ellipsosporum. We also have produced CV-N recombinantly by expression of a corresponding DNA sequ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::795c43f71b229cbdfeac4a0c1f4f3f55
https://europepmc.org/articles/PMC163952/
https://europepmc.org/articles/PMC163952/
Publikováno v:
Antiviral research. 33(2)
Prostratin, a non-tumor-promoting phorbol ester, inhibited human immunodeficiency virus (HIV)-induced cell killing and viral replication in a variety of acutely-infected cell systems. The potency and degree of cytoprotection was dependent on both vir
Autor:
Robert W. Buckheit, C Lackman-Smith, Michael R. Boyd, M J Currens, Y F Hallock, J B McMahon, R J Gulakowski
Publikováno v:
Antimicrobial agents and chemotherapy. 39(2)
Studies of the mechanism of action of michellamine B, a novel anti-human immunodeficiency virus (HIV) alkaloid from the tropical plant Ancistrocladus korupensis, have revealed that the compound acts at two distinct stages of the HIV life cycle. The c
Autor:
Mckee, T. C., Cardellina Ii, J. H., Riccio, R., D Auria, M. V., Maria Iorizzi, Minale, L., Moran, R. A., Gulakowski, R. J., Mcmahon, J. B., Buckheit Jr, R. W., Snader, K. M., Boyd, M. R.
Publikováno v:
Scopus-Elsevier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::c6132d205ff7039bf5ef7a8c8549c062
http://hdl.handle.net/11695/2811
http://hdl.handle.net/11695/2811