Zobrazeno 1 - 10
of 50
pro vyhledávání: '"R J Cotter"'
Publikováno v:
The Journal of Immunology. 158:2183-2191
One of the hallmarks of class I(A) molecules is their ability to bind and present a wide array of peptides to CD8 T cells. This diversity is consistent with their ability to restrict a variety of pathogenic peptide epitopes as well as elicit strong t
Autor:
R L Heinrikson, J D Lowenson, I M Reardon, H A Zürcher-Neely, R J Cotter, Rong Wang, Melvyn J. Ball, Steven Clarke, C Wolkow, Alex E. Roher
Publikováno v:
Journal of Biological Chemistry. 268:3072-3083
The structure of beta-amyloid (beta A) from Alzheimer disease brains was examined to determine if post-translational modifications might be linked to the abnormal deposition of this peptide in the diseased tissue. The beta A peptides were isolated fr
Publikováno v:
The Journal of biological chemistry. 276(46)
Attachment of the cationic sugar 4-amino-4-deoxy-l-arabinose (l-Ara4N) to lipid A is required for the maintenance of polymyxin resistance in Escherichia coli and Salmonella typhimurium. The enzymes that synthesize l-Ara4N and transfer it to lipid A h
Publikováno v:
The Journal of biological chemistry. 276(46)
Lipid A of Salmonella typhimurium can be resolved into multiple molecular species. Many of these substances are more polar than the predominant hexa-acylated lipid A 1,4'-bisphosphate of Escherichia coli K-12. By using new isolation methods, we have
Publikováno v:
The Journal of biological chemistry. 276(46)
Polymyxin-resistant mutants of Escherichia coli and Salmonella typhimurium accumulate a novel minor lipid that can donate 4-amino-4-deoxy-l-arabinose units (l-Ara4N) to lipid A. We now report the purification of this lipid from a pss(-) pmrA(C) mutan
Publikováno v:
The Journal of biological chemistry. 276(22)
Chlamydia trachomatis lipid A is unusual in that it is acylated with myristoyl chains at the glucosamine 3 and 3' positions. We have cloned and expressed the gene encoding UDP-N-acetylglucosamine 3-O-acyltransferase of C. trachomatis (CtlpxA), the fi
Autor:
R S, Naik, O H, Branch, A S, Woods, M, Vijaykumar, D J, Perkins, B L, Nahlen, A A, Lal, R J, Cotter, C E, Costello, C F, Ockenhouse, E A, Davidson, D C, Gowda
Publikováno v:
The Journal of Experimental Medicine
Induction of proinflammatory cytokine responses by glycosylphosphatidylinositols (GPIs) of intraerythrocytic Plasmodium falciparum is believed to contribute to malaria pathogenesis. In this study, we purified the GPIs of P. falciparum to homogeneity
Publikováno v:
The Journal of biological chemistry. 276(2)
Certain strains of Escherichia coli and Salmonella contain lipopolysaccharide (LPS) modified with a phosphoethanolamine (pEtN) group at position 7 of the outer 3-deoxy-d-manno-octulosonic acid (Kdo) residue. Using the heptose-deficient E. coli mutant
Publikováno v:
The Journal of biological chemistry. 275(42)
Lipid A molecules of certain Gram-negative bacteria, including Salmonella typhimurium and Pseudomonas aeruginosa, may contain secondary S-2-hydroxyacyl chains. S. typhimurium has recently been shown to synthesize its S-2-hydroxymyristate-modified lip
Publikováno v:
Journal of mass spectrometry : JMS. 35(5)