Zobrazeno 1 - 10
of 76
pro vyhledávání: '"R J Bull"'
Autor:
R J Bull, Joseph A. Cotruvo
Publikováno v:
Journal - American Water Works Association. 105:E709-E720
Risk assessments for bromate (BrO3-) in drinking water are based on linear extrapolation from the total incidence of tumors in male rats. The only genotoxic effects that might result from carcinogenic doses of BrO3- in vivo are the formation of 8-oxo
Publikováno v:
Toxicological Sciences. 45:33-41
Autor:
KARLA D. THRALL, R. J. BULL
Publikováno v:
Toxicological Sciences. 15:75-81
Publikováno v:
Toxicology. 130(2-3)
Dichloroacetate (DCA) is a by-product of drinking water chlorination. Administration of DCA in drinking water results in accumulation of glycogen in the liver of B6C3F1 mice. To investigate the processes affecting liver glycogen accumulation, male B6
Publikováno v:
Chronic diseases in Canada. 19(3)
Studies of water chlorination by-products have suggested a possible increased risk of bladder and colon cancers, as well as adverse reproductive and developmental effects such as increased spontaneous abortion rates and fetal anomalies. A workshop fo
Publikováno v:
Journal of toxicology and environmental health. Part A. 55(2)
Concerns have been raised over the use of iodine for disinfecting drinking water on extended space flights. Most fears revolve around effects of iodide on thyroid function. iodine (I2) is the form used in drinking-water disinfection. Risk assessments
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 25(5)
Trichloroacetic acid (TCA) is a metabolite of trichloroethylene (TRI) thought to contribute to its hepatocarcinogenic effects in mice. Recent studies have shown that peak blood concentrations of TCA do not occur until approximately 12 hr after an ora
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 23(12)
Trichloroacetate (TCA), dichloroacetate (DCA), and bromodichloroacetate (BDCA) are byproducts of the chlorination of drinking water. TCA acts primarily as a peroxisome proliferator, but DCA produces tumors at doses less than required for peroxisome p
Publikováno v:
Journal - American Water Works Association. 85(3)
The general approach to assessment of risk from chemical contaminants in drinking water involves three steps: hazard identification, exposure assessment, and dose-response assessment. Traditionally, the risks to humans associated with different level
Publikováno v:
Journal - American Water Works Association. 85(3)
In order to minimize the levels of potentially toxic disinfectants and disinfection by-products in treated water while maintaining adequate protection against microbiological contamination, the total risks associated with disinfection have to be meas