Zobrazeno 1 - 10
of 47
pro vyhledávání: '"R J, van de Griend"'
Autor:
I A, Haagen, A J, Geerars, W B, de Lau, M R, Clark, R J, van de Griend, B J, Bast, B C, de Gast
Publikováno v:
Blood. 84:556-563
To develop an effective tumor immunotherapy for B-lineage non-Hodgkin's lymphoma (NHL) and acute lymphoblastic leukemia (ALL), a bispecific monoclonal antibody (BsAb) has been generated with the first specificity for the CD3 epsilon-chain and the sec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a76c071586014083b9acf7f0681b2fa
https://doi.org/10.1182/blood.v84.2.556.bloodjournal842556
https://doi.org/10.1182/blood.v84.2.556.bloodjournal842556
Autor:
Gert Jan Fleuren, H. H. Van Ravenswaay Claasen, Sven O. Warnaar, R. J. van de Griend, R. L. H. Bolhuis, Delia Mezzanzanica
Publikováno v:
International Journal of Cancer. 55:128-136
OV-TL3 and MOv 18 MAbs, due to their restricted specificity, have been successfully used to visualize ovarian cancer in patients and might therefore be used to develop therapies for ovarian cancer. The bi-specific MAbs alpha T3/OC2 and alpha OC/TR (b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::032215c3efea5a65d7b283d4fa10e575
https://doi.org/10.1002/ijc.2910550123
https://doi.org/10.1002/ijc.2910550123
Autor:
Gert Jan Fleuren, J. D. H. Van Eendenburg, Arko Gorter, W. H. B. Haasnoot, R. J. van de Griend
Publikováno v:
Journal of Immunological Methods. 161:145-150
In the present study we have measured the feasibility of producing high amounts of bi-specific monoclonal antibodies (MAb) for therapeutic purposes using a hollow-fibre bioreactor. We have studied the isotype composition and functional capacity of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b75d1f761d5cf31daf457ffea17df585
https://doi.org/10.1016/0022-1759(93)90289-j
https://doi.org/10.1016/0022-1759(93)90289-j
Publikováno v:
Acta Haematologica. 83:193-197
Lymphocytes from children with Chediak-Higashi syndrome (CHS) have impaired natural killer (NK) activity and lack antibody-dependent cell-mediated cytotoxicity. Study of T cells bearing an alternate T cell receptor comprised of gamma- and delta-chain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae0f9916dbe20b1e121f794f2a358b9
https://doi.org/10.1159/000205212
https://doi.org/10.1159/000205212
Autor:
Jan W. Gratama, Eric Braakman, R. J. van de Griend, C. P. M. Ronteltap, Cor H. J. Lamers, Gerrit Stoter, Jean Bénard, R. L. H. Bolhuis
Publikováno v:
International journal of cancer. 51(6)
We investigated the optimal culture conditions (i.e., activation procedure, medium composition and type of culture vessel) for rapid in vitro expansion of large numbers (>5 × 109) of blood T lymphocytes. These expanded lymphocytes can be targeted to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65b3608557ded47944c26d8da1b6feca
https://pubmed.ncbi.nlm.nih.gov/1386349
https://pubmed.ncbi.nlm.nih.gov/1386349
SUMMARY We have isolated tumour-infiltrating lymphocytes (TIL) clones hum a patient with renal cell cancer. The cloning frequency and the effector function were measured. No difference in cloning frequency (r2= 0·97, frequency =1:13) was observed be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da5cdd024720475fa7e8e1c60699a0e
https://europepmc.org/articles/PMC1554219/
https://europepmc.org/articles/PMC1554219/
Publikováno v:
The Journal of Immunology. 132:3185-3191
Cloned lymphoid cell lines showing cytolytic activity were derived from natural killer (NK) cell-enriched cell fractions obtained by fluorescence-activated cell sorting of cells that reacted with B73 .1, an NK cell-specific monoclonal antibody (MCA).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01290920a7f996b4378be1dfc70143d5
https://doi.org/10.4049/jimmunol.132.6.3185
https://doi.org/10.4049/jimmunol.132.6.3185
Autor:
H G de Bruin, A Astaldi, T Leupers, R J van de Griend, L J Dooren, P T Schellekens, H J Tanke, M Roos, J M Vossen
Publikováno v:
The Journal of Immunology. 127:244-251
The relative distribution of T cell subsets, as defined by the monoclonal antibodies OKT, was analyzed in peripheral blood lymphocytes of 8 children after bone marrow transplantation for aplastic anemia. The percentage of peripheral blood lymphocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d1157edad0d73e78d523405685ca772
https://doi.org/10.4049/jimmunol.127.1.244
https://doi.org/10.4049/jimmunol.127.1.244
Autor:
R. L. H. Bolhuis, R. J. Van De Griend
Publikováno v:
Transplantation. 38:401-406
The availability of large numbers of functionally defined cloned T cells would facilitate biochemical and molecular studies and might be a prerequisite for in vivo immunotherapy with cytotoxic lymphocytes. Exogenous interleukin-2 (IL-2) is generally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d97934a5e2503ae09bfd33ceeea6743
https://doi.org/10.1097/00007890-198410000-00017
https://doi.org/10.1097/00007890-198410000-00017
Publikováno v:
The Journal of Immunology. 136:3939-3944
The 50 KD sheep red blood cell antigen receptor CD2 is the earliest T cell differentiation marker and is present on all blood-derived T cells, including natural killer (NK) cells. The CD2 antigen is also known to serve as an important activation site
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cce43852af47e6054e364bef05f36e79
https://doi.org/10.4049/jimmunol.136.11.3939
https://doi.org/10.4049/jimmunol.136.11.3939