Zobrazeno 1 - 10
of 24
pro vyhledávání: '"R J, Uhing"'
Publikováno v:
Biochemical Journal. 284:367-375
Phosphatidylcholine (PC) hydrolysis has been shown to occur in hormone-stimulated cells and represents a potential metabolic source, in addition to phosphoinositides, for the generation of diradylglycerols (DG). We performed studies in order to quant
Publikováno v:
The Journal of Immunology. 145:684-689
Activation of mononuclear phagocytes for a variety of functional responses is potentiated by prior exposure to IFN-gamma. Inasmuch as protein kinase C has been suggested to mediate several of these responses, we have examined the effects of IFN-gamma
Publikováno v:
The Journal of biological chemistry. 266(24)
Messenger RNA levels for the alpha subunit of G-proteins expressed in adipocytes of lean and obese (ob/ob) mice were compared with relative levels of the encoded proteins. Using both toxin labeling and Western blots, expression of Gs alpha, Gi alpha-
Publikováno v:
The Journal of biological chemistry. 266(16)
Treatment of murine peritoneal macrophages with 100 nM prostaglandin E2 (PGE2) produced a rapid biphasic increase in intracellular cAMP that was maximal at 1 min and sustained through 20 min. Pretreatment of macrophages with 100 ng/ml of lipopolysacc
Publikováno v:
The Journal of biological chemistry. 265(21)
The ability of interferon-gamma (IFN gamma) to increase class II major histocompatibility complex (class II MHC) gene products in murine macrophages involves activation of Na+/H+ exchange (Prpic V., Yu, S. F., Figueiredo, F., Hollenbach, P. W., Gawdi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 145(2)
Activation of mononuclear phagocytes for a variety of functional responses is potentiated by prior exposure to IFN-gamma. Inasmuch as protein kinase C has been suggested to mediate several of these responses, we have examined the effects of IFN-gamma
Publikováno v:
Journal of Biological Chemistry. 254:3166-3169
The activity of glycogen phosphorylase is controlled by two nucleotide sites. We have found that organic solvents affect the regulatory properties of phosphorylase by altering the binding at these two sites. At the activator site, the Ka for AMP is l
Publikováno v:
Journal of Biological Chemistry. 261:2140-2146
Calcium-sensitive inositide release in a purified rat liver plasma membrane preparation is increased by calcium-mobilizing hormones in the presence of guanine nucleotides. Vasopressin-stimulated inositide release is evident in the presence of GTP or
Publikováno v:
Journal of Biological Chemistry. 260:2011-2014
Recent studies with viral oncogene tyrosine kinases have suggested that these kinases may phosphorylate phosphoinositides and diacylglycerol. Since the receptors for insulin and epidermal growth factor (EGF) also possess tyrosine kinase activity, we
Publikováno v:
Journal of Biological Chemistry. 254:8263-8269