Zobrazeno 1 - 10
of 45
pro vyhledávání: '"R J, Summers"'
Autor:
R. J. Summers, V. R. Srinivasan
Publikováno v:
Continuous Cultures of Cells ISBN: 9781351070874
Continuous Cultures of Cells ISBN: 9780429291692
Continuous Cultures of Cells ISBN: 9780429291692
The application of continuous cultivation of microorganisms is a novel concept. Initial attempts were made in the development of such processes at the beginning of this century; however, the results were unsatisfactory. The setbacks commonly encounte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9506e6f89167e70e2b92acb035934ae4
https://doi.org/10.1201/9781351070874-5
https://doi.org/10.1201/9781351070874-5
Autor:
R J, Summers
Publikováno v:
British journal of pharmacology. 165(6)
As our knowledge and understanding of the way in which GPCRs operate continues to grow rapidly, many new opportunities are emerging to develop novel therapeutic agents. This themed issue of the British Journal of Pharmacology contains a series of pap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::92dcdeba2d72a0c4ad44d1ede9a11c1b
https://pubmed.ncbi.nlm.nih.gov/21950323
https://pubmed.ncbi.nlm.nih.gov/21950323
Autor:
R J, Summers
Publikováno v:
British journal of pharmacology. 155(3)
Beta-Adrenoceptors are one of the most widely studied groups of G-protein-coupled receptors but continue to provide surprises and insights that have general relevance to pharmacology. Atypical pharmacologies have been described for ligands formerly (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bd3a1e95e2975394de722c1e22c6e4ad
https://pubmed.ncbi.nlm.nih.gov/18641673
https://pubmed.ncbi.nlm.nih.gov/18641673
Autor:
M E, Gibbs, R J, Summers
Publikováno v:
The European journal of neuroscience. 14(8)
Investigation of the effects of the different adrenoceptor (AR) subtypes in memory formation may reveal discrete actions of noradrenaline in memory modulation and storage mediated through particular AR subtypes. Noradrenaline injected intracerebrally
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a737484c8ae9bf29f84387aeebaa69de
https://pubmed.ncbi.nlm.nih.gov/11703465
https://pubmed.ncbi.nlm.nih.gov/11703465
Autor:
M N, Mathieu, J D, Wade, B, Catimel, C P, Bond, E C, Nice, R J, Summers, L, Otvos, G W, Tregear
Publikováno v:
The journal of peptide research : official journal of the American Peptide Society. 57(5)
Biotin-avidin immobilization can be a useful tool in structure-function studies of hormone receptors. A crucial step is the preparation of a specifically biotinylated hormone that is able to bind to its receptor while leaving the biotin group free fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::273a496222bad4125d687eccf7bc865c
https://pubmed.ncbi.nlm.nih.gov/11350597
https://pubmed.ncbi.nlm.nih.gov/11350597
Publikováno v:
Journal of peptide science : an official publication of the European Peptide Society. 6(5)
The 'template-assembled synthetic protein' (TASP) concept provides a simple and elegant approach for the preparation of analogues that retain key structural elements. We have synthesized TASP molecules containing the putative active site of relaxin,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::415000d0ccecad9cbcbd42e3f0d33719
https://pubmed.ncbi.nlm.nih.gov/10823492
https://pubmed.ncbi.nlm.nih.gov/10823492
Publikováno v:
British journal of pharmacology. 129(6)
1. This study examines the relationship between beta(3a)- and beta(3b)-adrenoceptor (AR) mRNA levels, beta(3)-AR binding and changes in ileum responses in mice treated with the beta(3)-AR agonist (R, R)-5-[2[[2-(3-chlorophenyl)-2-hydroxyethyl]-amino]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3cb8563aa74929d71864ebabdc320779
https://pubmed.ncbi.nlm.nih.gov/10725275
https://pubmed.ncbi.nlm.nih.gov/10725275
Autor:
A R, Kompa, R J, Summers
Publikováno v:
British journal of pharmacology. 128(7)
1. Cardiostimulant effects of the non-conventional partial agonist, CGP 12177A, are mediated by a receptor distinct from the beta3-adrenoceptor and termed the putative beta4-adrenoceptor. Using a rat model of cardiac failure, induced by myocardial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::35991fdb60b34abc0e75ef05ce2cc617
https://pubmed.ncbi.nlm.nih.gov/10602318
https://pubmed.ncbi.nlm.nih.gov/10602318
Publikováno v:
British journal of pharmacology. 127(6)
The beta3-adrenoceptor (AR) differs from the beta1-AR and beta2-ARs in having introns within and downstream of the coding block. This study demonstrates two splice variants of the mouse beta3-AR which differ within the coding region. Reverse transcri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0466d8c557c7aabe83f440702897b498
https://pubmed.ncbi.nlm.nih.gov/10455305
https://pubmed.ncbi.nlm.nih.gov/10455305
Autor:
L, McMartin, R J, Summers
Publikováno v:
British journal of pharmacology. 127(4)
1. This study examined beta-adrenoceptor signalling in cardiac tissues following infusion of isoprenaline (400 microg kg(-1) h(-1)) or vehicle to rats for 14 days. 2. Isoprenaline infusion caused marked hypertrophy of atria and ventricles and reduced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cd372072de45a736a17edf134c44a76f
https://pubmed.ncbi.nlm.nih.gov/10433510
https://pubmed.ncbi.nlm.nih.gov/10433510