Výsledky vyhledávání - "R J, Scheper"

Hypertrophic and keloid scars fail to progress from the CD34

Autor: G C, Limandjaja, J M, Belien, R J, Scheper, F B, Niessen, S, Gibbs

Publikováno v: The British journal of dermatologyReferences. 182(4)

Our understanding of the pathogenesis underlying keloid scar formation is still very limited, and the morphological distinction between hypertrophic and keloid scars remains difficult.To test whether hypertrophic and keloid scars may reflect an inabi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::383ab82e5d18766224630c65cedaf0c8
https://pubmed.ncbi.nlm.nih.gov/31494925

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The vault complex

Autor: Pieter Sonneveld, A. T. M. van der Zon, R. J. Scheper, Marieke H. Mossink, Erik A.C. Wiemer

Publikováno v: van Zon, A, Mossink, MH, Scheper, R J, Sonneveld, P & Wiemer, EA 2003, ' The vault complex. ', Cellular and Molecular Life Sciences, vol. 60, no. 9, pp. 1828-37 . https://doi.org/10.1007/s00018-003-3030-y
Cellular and Molecular Life Sciences, 60, 1828-1837. Birkhäuser
Cellular and Molecular Life Sciences, 60(9), 1828-37. Birkhauser Verlag Basel

Vaults are large ribonucleoprotein particles found in eukaryotic cells. They are composed of multiple copies of a Mr 100,000 major vault protein and two minor vault proteins of Mr 193,000 and 240,000, as well as small untranslated RNAs of 86-141 base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::758479e0326853421be41f3668e315e1
https://pure.eur.nl/en/publications/55512b4d-b53b-4fd5-95a9-a8b9084b6b65

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Multiple Human Vault RNAs

Autor: M. Schoester, Pieter Sonneveld, Erik A.C. Wiemer, R. J. Scheper, Arend van Zon, George L. Scheffer, Marieke H. Mossink

Publikováno v: Journal of Biological Chemistry. 276:37715-37721

Human vaults are intracellular ribonucleoprotein particles believed to be involved in multidrug resistance. The complex consists of a major vault protein (MVP), two minor vault proteins (VPARP and TEP1), and several small untranslated RNA molecules.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::94334ce653156b5da70c0344e7bf20a3
https://doi.org/10.1074/jbc.m106055200

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Up-regulation of vaults may be necessary but not sufficient for multidrug resistance

Autor: R. J. Scheper, Valerie A. Kickhoefer, Andrew G. Stephen, Michael J. LaFemina, Leonard H. Rome, Amara C. Siva, Sujna Raval-Fernandes

Publikováno v: International Journal of Cancer. 92:195-202

Vaults are ribonucleoprotein complexes comprised of the 100 kDa major vault protein (MVP), the 2 high m.w. vault proteins p193 (VPARP) and p240 (TEP1) and an untranslated small RNA (vRNA). Increased levels of MVP, vault-associated vRNA and vaults hav

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6dcdfd769002f5676f0d3afc5797f928
https://doi.org/10.1002/1097-0215(200102)9999:9999<::aid-ijc1168>3.0.co

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Multiple gene expression analysis reveals distinct differences between G2 and G3 stage breast cancers, and correlations of PKC η with MDR1, MRP and LRP gene expression

Autor: J Beck, R Kandolf, J. Dietl, Dietrich Niethammer, Peter Bader, Dorothee Brügger, C Liu, R. J. Scheper, Volker Gekeler, B. Bohnet

Publikováno v: British Journal of Cancer

A possible link between protein kinase C (PKC) and P-glycoprotein (P-gp)-mediated-multidrug resistance (MDR) was assumed from studies on MDR cell lines selected in vitro. The functional relevance of PKC for the MDR phenotype remains unclear, and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5173b42ad67470d504e82beafcca915f
https://doi.org/10.1038/bjc.1998.13

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Booster-Dependent Alterations of the Subsets of T Lymphocytes and Eosinophils in the Bronchi of Immunized Guinea Pigs

Autor: B. Boris Vargaftig, David Baker, J.R. Lapa e Silva, Claude-Marie Bachelet, R. J. Scheper, Marina Pretolani

Publikováno v: International Archives of Allergy and Immunology. 99:350-353

We investigated whether guinea pigs sensitized to ovalbumin show changes in T cells in the bronchial wall and whether they correlate with eosinophil migration. Animals received two injections of 10 µg ovalbumin in Al(OH)3 with a 2-week interval. Lun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945bac5fb8d5c3ae9f413437dffbabe8
https://doi.org/10.1159/000236282

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The proteasome inhibitor bortezomib inhibits the release of NFkappaB-inducible cytokines and induces apoptosis of activated T cells from rheumatoid arthritis patients

Autor: J W, van der Heijden, R, Oerlemans, W F, Lems, R J, Scheper, B A C, Dijkmans, G, Jansen

Publikováno v: Clinical and experimental rheumatology. 27(1)

The proteasome is a multicatalytic proteinase complex regulating the intracellular breakdown of many proteins, including those mediating the activation of pro-inflammatory signaling pathways (e.g. NFkappaB), cell proliferation and survival. Conceptua

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::728b9339cf83bd62992e761c5afd62b1
https://pubmed.ncbi.nlm.nih.gov/19327235

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Autologous full-thickness skin substitute for healing chronic wounds

Autor: S, Gibbs, H M, van den Hoogenband, G, Kirtschig, C D, Richters, S W, Spiekstra, M, Breetveld, R J, Scheper, E M, de Boer

Publikováno v: The British journal of dermatology. 155(2)

Chronic wounds represent a major problem to our society. Therefore, advanced wound-healing strategies for the treatment of these wounds are expanding into the field of tissue engineering.To develop a novel tissue-engineered, autologous, full-thicknes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65a5fec2b91829227da808737d27dd78
https://pubmed.ncbi.nlm.nih.gov/16882162

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Comparison of two in vitro dendritic cell maturation models for screening contact sensitizers using a panel of methacrylates

Autor: T, Rustemeyer, M, Preuss, B M E, von Blomberg, P K, Das, R J, Scheper

Publikováno v: Experimental dermatology. 12(5)

Allergen-induced emigration and maturation of dendritic cells (DC) are pivotal steps in sparking off allergic contact dermatitis. In vitro models, reflecting these steps, may provide tools for assessment of sensitizing capacities of putative contact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7083f625f8df6dc0e8b1bd1f9f3ab962
https://pubmed.ncbi.nlm.nih.gov/14705810

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