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Expression of Bacillus subtilis levanase gene in Lactobacilus plantarum and Lactobacillus casei

Autor: R. J. Leer, Erich E. Wanker, Peter H. Pouwels, Helmut Schwab

Publikováno v: Applied Microbiology and Biotechnology. 43:297-303

Two Lactobacillus-Escherichia coli shuttle vectors, harbouring the levanase gene from Bacillus subtilis under the control of its own promoter (pLPEW1) or behind the E. coli tac promoter (pESIEW2), were constructed. Lactobacillus plantarum showed the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272416b9f5c43e04ed59ee3a77051a6d
https://doi.org/10.1007/bf00172828

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Lactobacilli as vehicles for targeting antigens to mucosal tissues by surface exposition of foreign antigens

Autor: P H, Pouwels, A, Vriesema, B, Martinez, F J, Tielen, J F, Seegers, R J, Leer, J, Jore, E, Smit

Publikováno v: Methods in enzymology. 336

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::916a9ef3c0cbb402a7f6d8bc9f3f92bd
https://pubmed.ncbi.nlm.nih.gov/11398413

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Engineering the microflora to vaccinate the mucosa: serum immunoglobulin G responses and activated draining cervical lymph nodes following mucosal application of tetanus toxin fragment C-expressing lactobacilli

Autor: D M, Shaw, B, Gaerthé, R J, Leer, J G, Van Der Stap, C, Smittenaar, M, Heijne Den Bak-Glashouwer, J E, Thole, F J, Tielen, P H, Pouwels, C E, Havenith

Publikováno v: Immunology. 100(4)

The delivery of antigens to mucosal-associated lymphoid tissues in paediatric and immunocompromised populations by safe, non-invasive vectors, such as commensal lactobacilli, represents a crucial improvement to prevailing vaccination options. In this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::da04ce43ca17e111847c2d5abf1eaee2
https://pubmed.ncbi.nlm.nih.gov/10929079

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