Zobrazeno 1 - 10
of 12
pro vyhledávání: '"R J, Labotka"'
Publikováno v:
American Journal of Physiology-Heart and Circulatory Physiology. 266:H1729-H1737
If a colloid osmotic (oncotic) pressure gradient develops across the myocyte membrane during the calcium paradox, adding an oncotic agent to the perfusate should be inhibitory. After 10-min perfusion with Ca(2+)-free Krebs-Henseleit (KH) buffer under
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43a92be532682421401713e8c5b59ebb
https://doi.org/10.1152/ajpheart.1994.266.5.h1729
https://doi.org/10.1152/ajpheart.1994.266.5.h1729
Publikováno v:
Biochemical pharmacology. 60(7)
Acetylation of hemoglobin by aspirin and other compounds has been of interest for the development of agents useful for the treatment of sickle cell disease. In the present study, we have used 2D NMR methods in combination with [1-(13)C-acetyl]salicyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8f8f2d2ca7a41848aabdf450cb1b3f4c
https://pubmed.ncbi.nlm.nih.gov/10974199
https://pubmed.ncbi.nlm.nih.gov/10974199
Autor:
K, Sazama, P J, DeChristopher, R, Dodd, C R, Harrison, I A, Shulman, E S, Cooper, R J, Labotka, H A, Oberman, C M, Zahn, A G, Greenburg, L, Stehling, K J, Lauenstein, T H, Price, L K, Williams
Publikováno v:
Archives of pathologylaboratory medicine. 124(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f4347f73f6c34706b969e2893017d9fc
https://pubmed.ncbi.nlm.nih.gov/10629134
https://pubmed.ncbi.nlm.nih.gov/10629134
Publikováno v:
The Journal of biological chemistry. 274(38)
The development of chemical modification agents that reduce the tendency of sickle hemoglobin (HbS) to aggregate represents an important chemotherapeutic goal. Methyl acetylphosphate (MAP) has been reported to bind to the 2,3-diphosphoglycerate (2,3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75aa87dcde479ebfd5e40acb60ad5e3f
https://pubmed.ncbi.nlm.nih.gov/10480863
https://pubmed.ncbi.nlm.nih.gov/10480863
Publikováno v:
Blood. 85(11)
Elevation of 2,3-bisphosphoglycerate (2,3-DPG) in sickle erthrocytes (SS RBCs) and concomitant acidification of the cell interior promote polymerization by decreasing the solubility (csat) of deoxyhemoglobin S. The antisickling effect of 2,3-DPG depl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::64a6390b88a9960eb5fc7c0a2ec9d9bb
https://pubmed.ncbi.nlm.nih.gov/7756662
https://pubmed.ncbi.nlm.nih.gov/7756662
Autor:
R. J. Labotka
Publikováno v:
JAMA: The Journal of the American Medical Association. 288:894
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a530d5f59d3627c9e0f87416a8831e6
https://doi.org/10.1001/jama.288.7.894-a
https://doi.org/10.1001/jama.288.7.894-a
Autor:
A Omachi, R J Labotka
Publikováno v:
Journal of Biological Chemistry. 262:305-311
The phosphate analogs are a series of chemically related small anions based upon tetrahedrally bonded phosphorus. Each compound is a mono- or disubstituted phosphorus oxyacid. These chemical substitutions lead to differences in the number and acidity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd1c2387bbed6b6d8fbc0ec8f5dc7186
https://doi.org/10.1016/s0021-9258(19)75927-4
https://doi.org/10.1016/s0021-9258(19)75927-4
Autor:
A L, Frank, R J, Labotka, S, Rao, L R, Frisone, P H, McVerry, J S, Samuelson, H, Maurer, R, Yogev
Publikováno v:
Pediatrics. 82(4)
Haemophilus influenzae type B vaccine is recommended for children 1.5 to 6 years of age with sickle cell anemia, but the adequacy of their response is unknown. A total of 69 children with sickle cell syndromes, 1.5 to 5.6 years of age, were immunized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::347da47fedaa0d5100d6da522b9aea95
https://pubmed.ncbi.nlm.nih.gov/3262857
https://pubmed.ncbi.nlm.nih.gov/3262857
Ovarian granulocytic sarcoma as the primary manifestation of acute infantile myelomonocytic leukemia
Publikováno v:
Cancer. 48(8)
The first known instance of granulocytic sarcoma of the ovary as the presenting manifestation of acute nonlymphocytic leukemia in infancy is reported. The clinical and laboratory findings for a 3-month-old infant who had anemia and a lower abdominal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0906d0daa679a38ca0fa3ccaeff9a1ea
https://pubmed.ncbi.nlm.nih.gov/6945145
https://pubmed.ncbi.nlm.nih.gov/6945145
Autor:
R J, Labotka, A, Omachi
Publikováno v:
Biomedica biochimica acta. 46(2-3)
The titratible carrier model for erythrocyte anion transport predicts that the pH dependence of titratible anion transport should differ considerably from that for monovalent or divalent anions. The effects of pH on titratible anion influx rates have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5589fd34750cd4f9cb9d37fe345379a
https://pubmed.ncbi.nlm.nih.gov/3593319
https://pubmed.ncbi.nlm.nih.gov/3593319