Zobrazeno 1 - 10
of 29
pro vyhledávání: '"R J, Feldmann"'
Publikováno v:
Journal of Biological Chemistry. 258:7017-7028
With the use of a computer graphics system, spacefilling models of mouse and rat testis lactate dehydrogenase C4 (LDH-C4) isozymes were constructed from amino acid sequence and published x-ray diffraction data. Thirty-two residues that differ between
Publikováno v:
Journal of Medicinal Chemistry. 18:539-545
This paper reports the application of pattern recognition and substructural analysis to the problem of predicting the antineoplastic activity of 24 test compounds in an experimental mouse brain tumor system based on 138 structurally diverse compounds
Publikováno v:
Journal of Biological Chemistry. 257:3875-3882
Computer-generated molecular models of the trypsin-like domains of blood coagulation factor IXa, Factor Xa, and thrombin have been prepared. These hypothetical models are based upon the sequence homology of the blood coagulation enzymes with the panc
Publikováno v:
The Journal of Immunology. 128:314-322
A monoclonal antibody (HyHEL-5), prepared to chicken lysozyme c by the method of Köhler and Milstein, identified an antigenic site (epitope) that was shared by the lysozymes of seven different species of galliform birds. The lysozymes of two gallifo
Publikováno v:
Journal of Biological Chemistry. 257:3189-3198
Monoclonal antibodies of high affinity (approximately 10(9) M-1) for sperm whale myoglobin were studied to pinpoint the antigenic determinants with which they interact. None of 6 different monoclonal antibodies tested reacted with any of the 3 CNBr c
Publikováno v:
Proceedings of the National Academy of Sciences. 80:4679-4683
It has been recently shown that malignant activation of the c-has/bas proto-oncogene in T24 human bladder carcinoma cells was mediated by a single point mutation. A deoxyguanosine located at position 35 of the first exon of this proto-oncogene was su
Autor:
D. A. Koniver, R. J. Feldmann
Publikováno v:
Journal of Chemical Documentation. 11:154-159
Percutaneous penetration of 14C hydrocortisone in man. II. Effect of certain bases and pretreatments
Autor:
R. J. Feldmann
Publikováno v:
Archives of Dermatology. 94:649-651
Publikováno v:
Oral Presentations.
Three dimensional structural models of the heavy chain of Factor Xa, the heavy chain of Factor IXa, and the B chain of thrombin have been developed using a computer molecular graphics display system. These models are based upon the sequence homology
Publikováno v:
Biochemistry. 15(1)
The relaxation rates of the carbon-bound protons and of the three assigned phosphorus resonances of propionyl-CoA were measured in solutions of free propionyl-CoA and of the transcarboxylase-propionyl-CoA complex. In free propionyl-CoA, analysis of t