Zobrazeno 1 - 10
of 58
pro vyhledávání: '"R J, Bergeron"'
Autor:
R J Bergeron, J Scott
Publikováno v:
Journal of Lipid Research, Vol 23, Iss 3, Pp 391-404 (1982)
The fluorescent cholesterol analogues, cholesta-5,7,9(11)triene-3-beta-ol (I) and ergosta-5,7,9(11)-22-tetraene-3-beta-ol (II), have been shown to be readily incorporated by various tissues and lipoproteins in rabbits maintained on diets supplemented
Externí odkaz:
https://doaj.org/article/3b6ace8aed994dcbb6fd9cf504c328c7
Publikováno v:
Blood. 79:1882-1890
A comparative study of the iron-clearing properties of subcutaneously (SC) administered deferoxamine (DFO) with those of orally administered 1,2-dimethyl-3-hydroxypyrid-4-one (CP20) and 1,2-diethyl-3-hydroxypyrid- 4-one (CP94) is presented. The studi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dec3267aa221c13aff193b4f71e9e40e
https://doi.org/10.1182/blood.v79.7.1882.bloodjournal7971882
https://doi.org/10.1182/blood.v79.7.1882.bloodjournal7971882
Publikováno v:
Digestive diseases and sciences. 46(12)
The evaluation of a group of polyamine analogs as agents to ameliorate diarrhea-predominant irritable bowel syndrome is described. Each compound was assessed when administered subcutaneously in a psychological stress-induced model of irritable bowel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac7146d9e3d104086b8fb0f48ac5d539
https://pubmed.ncbi.nlm.nih.gov/11768250
https://pubmed.ncbi.nlm.nih.gov/11768250
Autor:
R J, Bergeron, J, Wiegand, J S, McManis, W R, Weimar, R E, Smith, S E, Algee, T L, Fannin, M A, Slusher, P S, Snyder
Publikováno v:
Journal of medicinal chemistry. 44(2)
The syntheses of a group of spermine polyamine analogues and their evaluation as antidiarrheals are described. Each compound was assessed in a rodent castor oil-induced diarrhea model for its ability to reduce stool output and weight loss in a dose-d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::53d41678f682e58d3c2112b0c6121b2b
https://pubmed.ncbi.nlm.nih.gov/11170633
https://pubmed.ncbi.nlm.nih.gov/11170633
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 27(12)
The pharmacokinetic behavior of three iron chelators based on the desferrithiocin (DFT) pharmacophore, (S)-4, 5-dihydro-2-(2-hydroxyphenyl)-4-thiazolecarboxylic acid (desmethyldesferrithiocin, DMDFT, 2); (S)-4,5-dihydro-2-(2, 4-dihydroxyphenyl)-4-thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e949fd09f06767cc95d7dc63a4bd3fc4
https://pubmed.ncbi.nlm.nih.gov/10570032
https://pubmed.ncbi.nlm.nih.gov/10570032
Autor:
D L, Kramer, S, Vujcic, P, Diegelman, J, Alderfer, J T, Miller, J D, Black, R J, Bergeron, C W, Porter
Publikováno v:
Cancer research. 59(6)
Although polyamines are well recognized for their critical involvement in cell growth, the cell cycle specificity of this requirement has not yet been characterized with respect to the newly delineated regulatory pathways. We recently reported that p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7c1a215667f16df54617ae11ac36420
https://pubmed.ncbi.nlm.nih.gov/10096560
https://pubmed.ncbi.nlm.nih.gov/10096560
Publikováno v:
Blood. 93(1)
To further examine the potential clinical usefulness of the hexadentate phenolic aminocarboxylate iron chelator N, N'-bis(2-hydroxybenzyl)ethylenediamine-N,N'-diacetic acid (HBED) for the chronic treatment of transfusional iron overload, we performed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::658f611e91accc6e6196d497d7aad469
https://pubmed.ncbi.nlm.nih.gov/9864183
https://pubmed.ncbi.nlm.nih.gov/9864183
Publikováno v:
Blood. 91(4)
To examine the potential clinical usefulness of the hexadentate phenolic aminocarboxylate iron chelator N, N-bis(2-hydroxybenzyl)ethylenediamine-N,N-diacetic acid (HBED) for the chronic treatment of transfusional iron overload, we compared the iron e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0759c998e9597a8b720f2d89390b7a47
https://pubmed.ncbi.nlm.nih.gov/9454776
https://pubmed.ncbi.nlm.nih.gov/9454776
Publikováno v:
The Prostate. 34(1)
The possibility was investigated that complex homeostatic mechanisms which maintain polyamine pools in prostate-derived tumors may differ from those which are typically seen in other tissues and tumors.Growth sensitivity and various regulatory respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0c6398a7957a1fde3628bbdf4d83a523
https://pubmed.ncbi.nlm.nih.gov/9428388
https://pubmed.ncbi.nlm.nih.gov/9428388
Autor:
D L, Kramer, M, Fogel-Petrovic, P, Diegelman, J M, Cooley, R J, Bernacki, J S, McManis, R J, Bergeron, C W, Porter
Publikováno v:
Cancer research. 57(24)
On the basis of encouraging preclinical findings, polyamine analogues have emerged as a novel class of experimental antitumor agents. The spermine derivative N1,N11-diethylnorspermine (DE-333, also known as DENSPM) is currently undergoing Phase I cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4ae7a25bf33de7f9173e91e3f3dd79f2
https://pubmed.ncbi.nlm.nih.gov/9407962
https://pubmed.ncbi.nlm.nih.gov/9407962