Human oral lectin ZG16B acts as a cell wall polysaccharide probe to decode host–microbe interactions with oral commensals

Autor: Soumi Ghosh, Christian P. Ahearn, Christine R. Isabella, Victoria M. Marando, Gregory J. Dodge, Helen Bartlett, Robert L. McPherson, Amanda E. Dugan, Shikha Jain, Lubov Neznanova, Hervé Tettelin, Rachel Putnik, Catherine L. Grimes, Stefan Ruhl, Laura L. Kiessling, Barbara Imperiali

Publikováno v: Proceedings of the National Academy of Sciences. 120

The oral microbiome is critical to human health and disease, yet the role that host salivary proteins play in maintaining oral health is unclear. A highly expressed gene in human salivary glands encodes the lectin zymogen granule protein 16 homolog B

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::18830197b934d150759c1eb81d8a39c5
https://doi.org/10.1073/pnas.2216304120

Stereoelectronic Effects Impact Glycan Recognition

Autor: Christine R. Isabella, Laura L. Kiessling, Caitlin M. McMahon, Paul Kosma, Ian W. Windsor, Ronald T. Raines

Publikováno v: J Am Chem Soc
PMC

Copyright © 2020 American Chemical Society. Recognition of distinct glycans is central to biology, and lectins mediate this function. Lectin glycan preferences are usually centered on specific monosaccharides. In contrast, human intelectin-1 (hItln-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2b425be348916b868953dc270a6e22
https://pubmed.ncbi.nlm.nih.gov/31930911

4CPS-178 Abstract withdrawn

Autor: R Isabella, S Radici, M Mazzari, S Lapadula, ML Giusto, L Di Castri, A Sartori, E Bazzoni, C Ercoli

Publikováno v: Section 4: Clinical Pharmacy Services.

Background The onset of depressive disorders in old age (≥65 years) involves very complex choices in the use of pharmacological treatments. Clinical case heterogeneity, aging-derived biological alterations determine a specific use of antidepressant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fb674f07bb5ddc8833e817e899a5c1ce
https://doi.org/10.1136/ejhpharm-2019-eahpconf.327

A Pipeline for Expression, Functionalization, and Characterization of Human Lectins Involved in Innate Immunity

Autor: Helen Bartlett, Roger C. Diehl, Laura L. Kiessling, Barbara Imperiali, Christine R. Isabella, Gregory Dodge, Amanda Dugan

Publikováno v: The FASEB Journal. 34:1-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b5906c94959634f57d36018321f63891
https://doi.org/10.1096/fasebj.2020.34.s1.09652

Joubert syndrome: a model for untangling recessive disorders with extreme genetic heterogeneity

Autor: Hamit Özyürek, N. de Lacy, Brian J. O'Roak, Tessa Rue, Jay Shendure, Evan A. Boyle, Phillip F. Chance, Angels García-Cazorla, Jennifer C. Dempsey, Dana M. Knutzen, Charles Marques Lourenço, I A Glass, Beyhan Tüysüz, Diana R. O’Day, Jonathan Adkins, Dan Doherty, Ruxandra Bachmann-Gagescu, Gisele E. Ishak, Radha Ramadevi A, Melissa A. Parisi, L Lingappa, Loreto Martorell, Abdulrahman Alswaid, G Haliloğlu, Ian G. Phelps, Christine R. Isabella, Meral Topçu, Nicholas T. Gorden

Publikováno v: Journal of Medical Genetics
JOURNAL OF MEDICAL GENETICS
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname

Bachmann-Gagescu, Ruxandra/0000-0002-3571-5271; O'Roak, Brian/0000-0002-4141-0095; Isabella, Christine/0000-0003-0786-7240; Blue, Elizabeth/0000-0002-0633-0305; , Beyhan/0000-0002-9620-5021 WOS: 000358443800002 PubMed: 26092869 Background Joubert syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10525a2bb15fc91d75c98785572f9870