Zobrazeno 1 - 10
of 13
pro vyhledávání: '"R I Macfarlan"'
Autor:
R I Macfarlan, B Dietzschold, T J Wiktor, M Kiel, R Houghten, R A Lerner, J G Sutcliffe, H Koprowski
Publikováno v:
The Journal of Immunology. 133:2748-2752
The antigenic structure of the rabies virus glycoprotein has been studied. A limited number of fragments were obtained by cyanogen bromide (CNBr) cleavage of viral glycoprotein, and eight large peptides were isolated by using sodium dodecyl sulfate (
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene
Autor:
Bernhard Dietzschold, R I Macfarlan, William H. Wunner, Marie-Paule Kieny, Tadeusz J. Wiktor, J P Lecocq, Richard Lathe, M Mackett, P J Curtis, K J Reagan
Publikováno v:
Proceedings of the National Academy of Sciences. 81:7194-7198
Inoculation of rabbits and mice with a vaccinia-rabies glycoprotein recombinant (V-RG) virus resulted in rapid induction of high concentrations of rabies virus-neutralizing antibodies and protection from severe intracerebral challenge with several st
Autor:
Tadeusz J. Wiktor, C.L. Smith, E. Golub, R I Macfarlan, Bernhard Dietzschold, William H. Wunner
Publikováno v:
Annales de l'Institut Pasteur / Virologie. 136:353-362
Resume Induire une reponse immunitaire a des virus rabiques est la fonction primordialed'un vaccin antirabique, qu'il s'agisse d'un traitement preventif chez les animaux et les humains ou d'un traitement en post-exposition pour l'homme. Le pic de sur
Publikováno v:
Scopus-Elsevier
Natural killer (NK) cells are rapidly elicited in the spleen and peritoneal cavity of mice inoculated intravenously or intraperitoneally with live Kunjin virus, and more slowly in the peritoneal cavity of mice inoculated intraperitoneally with Formal
Autor:
Tadeusz J. Wiktor, Charles E. Rupprecht, Bernhard Dietzschold, William H. Wunner, R I Macfarlan
Publikováno v:
Annales de l'Institut Pasteur / Virologie. 136:405-411
Summary The ability to construct recombinant viruses expressing foreign genes clearlyhas great potential for vaccine development. In the case of rabies, the V-RG virus has proved to be highly immunogenic, and has outperformed conventional rabies vacc
Autor:
M J Torres-Anjel, John Q. Trojanowski, Tadeusz J. Wiktor, Hilary Koprowski, R I Macfarlan, Bernhard Dietzschold, William H. Wunner
Publikováno v:
Journal of virology. 56(1)
Pathogenic parental rabies virus and apathogenic variant virus were shown to differ in their ability to infect neurons in vivo and neuroblastoma cells in vitro. After intracerebral inoculation, the distribution of infected neurons in the brain was si
Autor:
R I, Macfarlan, B, Dietzschold, T J, Wiktor, M, Kiel, R, Houghten, R A, Lerner, J G, Sutcliffe, H, Koprowski
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 133(5)
The antigenic structure of the rabies virus glycoprotein has been studied. A limited number of fragments were obtained by cyanogen bromide (CNBr) cleavage of viral glycoprotein, and eight large peptides were isolated by using sodium dodecyl sulfate (
After rabies virus glycoprotein was treated with CNBr, the peptide mixture was fractionated by preparative sodium dodecyl sulfate-polyacrylamide gel electrophoresis. CNBr-cleaved peptide fragments were resolved into seven peptide bands under reducing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d963925fc9aa8339eba2425f48e0d615
https://europepmc.org/articles/PMC256303/
https://europepmc.org/articles/PMC256303/
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 119(5)
Two new types of cell-mediated immune cytolysis of togavirus-infected cells are compared. The peritoneal cavity of mice 2 days after infection contains a nonadherent, non-phagocytic, non-O-bearing, trypsin-resistant, EDTA-sensitive cell displaying br
Publikováno v:
Rabies in the Tropics ISBN: 9783540138266
Cell-mediated immunity plays a major role in pathogenicity of rabies virus infection, and is probably also involved in the mechanism of post-exposure rabies prophylaxis. Live-attenuated rabies virus vaccines (ERA, HEP, Kelev) induce a strong cytotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e3ed7ea4d290dc59c71982e503b4ec5d
https://doi.org/10.1007/978-3-642-70060-6_3
https://doi.org/10.1007/978-3-642-70060-6_3