Výsledky vyhledávání

Influence of trehalose on the molecular chaperone activity of p26, a small heat shock/alpha-crystallin protein

Autor: R I, Viner, J S, Clegg

Publikováno v: Cell stresschaperones. 6(2)

Encysted embryos of the primitive crustacean Artemia franciscana are among the most resistant of all multicellular eukaryotes to environmental stress, in part due to massive amounts of a small heat shock/alpha-crystallin protein (p26) that acts as a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5fdad3ed097aa7739a41b9dd9c866a86
https://pubmed.ncbi.nlm.nih.gov/11599574

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Protein modification during biological aging: selective tyrosine nitration of the SERCA2a isoform of the sarcoplasmic reticulum Ca2+-ATPase in skeletal muscle

Autor: R I, Viner, D A, Ferrington, T D, Williams, D J, Bigelow, C, Schöneich

Publikováno v: The Biochemical journal. 340

The accumulation of covalently modified proteins is an important hallmark of biological aging, but relatively few studies have addressed the detailed molecular-chemical changes and processes responsible for the modification of specific protein target

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c10fcd4fe99dbc7d634d5ae5606e9771
https://pubmed.ncbi.nlm.nih.gov/10359649

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Benzophenone-sensitized photooxidation of sarcoplasmic reticulum membranes: site-specific modification of the Ca(2+)-ATPase

Autor: A K, Krainev, R I, Viner, D J, Bigelow

Publikováno v: Free radical biologymedicine. 23(7)

Benzophenone (BP) was used as a photosensitizer to initiate lipid peroxidation in model and native biological membranes at concentrations of BP that do not perturb bilayer structure, as assessed by stearic acid spin label dynamics. Illumination of BP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0a6d7bc993992773d11639d0a42d4311
https://pubmed.ncbi.nlm.nih.gov/9358244

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4-Androstene-317-dione metabolism in vitro in the liver microsomes of species of bullhead endemic to Lake Baikal under normal conditions and in mono-oxygenase induction by 3-methylcholanthrene and aroclor 1254

Autor: R I, Viner, A B, Kupchinskiĭ

Publikováno v: Nauchnye doklady vysshei shkoly. Biologicheskie nauki. (1)

The metabolism in vitro of 4-androstene 3,17-dione--one of the steroid hormones--has been studied in liver microsomes of three species of bullhead: Cottocomephorus grewingki Dyb., Paracottus Kneri Dyb., Paracottus Kessleri Dyb. from Lake Baikal under

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1f834547e34e96a73fe415408ca2f313
https://pubmed.ncbi.nlm.nih.gov/8507738

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[An immunochemical analysis of the induction of cytochrome P-450 isoforms in the liver of fresh-water fishes by 3-methylcholanthrene, beta-naphthoflavone and aroclor 1254]

Autor: S V, Kotelevtsev, L V, Ponomarëva, K N, Novikov, R I, Viner, Iu P, Kozlov, O G, Khatsenko, D V, Mitrofanov

Publikováno v: Nauchnye doklady vysshei shkoly. Biologicheskie nauki. (5)

The cytochrome P-450 isoforms have been studied in liver microsomes of some fish species from Lake Baikal. Using the inhibitory analysis of microsomal monooxygenase activities carried out by the specific polyclonal antibodies it has been shown that 3

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a37c883084d7d37a8c5f87f6a6f2b10
https://pubmed.ncbi.nlm.nih.gov/2118391

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Hydroxylation products of hydrophobic xenobiotics and cytochrome P-450 stabilizers in hepatocytes

Autor: L. D. Luk'yanova, Valerian E. Kagan, Novikov Kn, R. I. Viner, A. T. Ugolev, A. M. Dudchenko

Publikováno v: Bulletin of Experimental Biology and Medicine. 98:1195-1198

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6ba24296542bc29515ee101d365e0419
https://doi.org/10.1007/bf00804295

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Does ?-tocopherol interact with the active site of cytochrome P-450 in liver microsomes?

Autor: Yu. P. Kozlov, Novikov Kn, Valerian E. Kagan, R. I. Viner

Publikováno v: Bulletin of Experimental Biology and Medicine. 103:336-339

The interaction of alpha-tocopherol (alpha-T) and its synthetic derivative 2,2,5,7,8-pentamethyl-6-hydroxy-chroman (PMC) with cytochrome P-450 system was studied in the rat liver microsomes. Spectral differentiations of type I, increase of NADPH oxid

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::14df5e0cf327d2429a0e539bc0aba7aa
https://doi.org/10.1007/bf00840554

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[Hydroxylation products of hydrophobic xenobiotics--stabilizers of cytochrome P-450 in the hepatocytes]

Autor: K N, Novikov, R I, Viner, A M, Dudchenko, A T, Ugolev, L D, Luk'ianova

Publikováno v: Biulleten' eksperimental'noi biologii i meditsiny. 98(9)

The effects of the hydroxylation product 3,4-benzo(a)pyrene and the free radical scavenger 1,2,3-trioxybenzene on cytochrome P-450 degradation in isolated rat hepatocytes induced by the Fe2+-ADP + NADPH system activating lipid peroxidation (LPO) were

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9b057aa64c09eea4cac2afd97b7bb5f7
https://pubmed.ncbi.nlm.nih.gov/6487785

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