Zobrazeno 1 - 2
of 2
pro vyhledávání: '"R I, Macias"'
Publikováno v:
International journal of cancer. 88(2)
Low water solubility and development of resistance are important drawbacks in the use of cisplatin as a cytostatic agent. A novel bile acid-cisplatin complex, Bamet-R2 [cis-diamminechlorocholylglycinateplatinum (II)], with liver vectoriality, has bee
Publikováno v:
International journal of cancer. 78(3)
The aim of this study was to investigate the ability of the new liver organotropic complex of cisplatin with glycocholate (GC), Bamet-R2, to interact with DNA, inhibit its replication and hence reduce tumor-cell proliferation. Changes in the electrop