Zobrazeno 1 - 10
of 325
pro vyhledávání: '"R Hosotani"'
Autor:
Masayuki Sho, Hiroyuki Isayama, N Yamada, S Nakamori, Yasushi Ichikawa, Chikuma Hamada, Ichinosuke Hyodo, Go Wakabayashi, Kensei Yamaguchi, Satoshi Takahashi, Akira Fukutomi, Hiroaki Yanagimoto, Hideo Baba, S. Ohkawa, Michiaki Unno, A Funakoshi, Y Tsuchiya, Masataka Ikeda, R Hosotani, N Egawa, Masahiro Tsuda, Yasuo Hamamoto, S. Matsumoto, Yasushi Omuro, Michitaka Nagase, Takuji Okusaka, G Watanabe, Hiroshi Ishii
Publikováno v:
British Journal of Cancer
Background: This randomised, open-label, multicenter phase II study compared progression-free survival (PFS) of S-1 plus oxaliplatin (SOX) with that of S-1 alone in patients with gemcitabine-refractory pancreatic cancer. Methods: Patients with confir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c402082321a04e2b4d5ab94cbde7b21
https://doi.org/10.1038/bjc.2015.103
https://doi.org/10.1038/bjc.2015.103
Autor:
Y, Miyamoto, R, Hosotani, R, Doi, M, Wada, J, Ida, S, Tsuji, M, Kawaguchi, S, Nakajima, H, Kobayashi, T, Masui, M, Imamura
Publikováno v:
Anticancer research. 21(4A)
We have examined the relationship between the expression and activation of the IL-6 receptor and the possible involvement of IL-6 in the resistance of radiation-induced apoptosis in pancreatic cancer cells. Levels of IL-6 in the incubation media meas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0d699373d3e36cbacbbfe3d570131db
https://pubmed.ncbi.nlm.nih.gov/11724306
https://pubmed.ncbi.nlm.nih.gov/11724306
Autor:
T, Masui, R, Hosotani, S, Tsuji, Y, Miyamoto, S, Yasuda, J, Ida, S, Nakajima, M, Kawaguchi, H, Kobayashi, M, Koizumi, E, Toyoda, S, Tulachan, S, Arii, R, Doi, M, Imamura
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 7(11)
METH-1/hADAMTS-1 and METH-2/hADAMTS-8 are recently identified genes that inhibit angiogenesis, and the murine homologue, ADAMTS-1, shows metalloproteinase function. Because the significance of METH-1 and METH-2 has not been determined in solid tumors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f5b0ffc9c5310b92a34d84982c2e7763
https://pubmed.ncbi.nlm.nih.gov/11705860
https://pubmed.ncbi.nlm.nih.gov/11705860
Publikováno v:
Nihon geka hokan. Archiv fur japanische Chirurgie. 68(3-4)
We have modified the perfused guinea pig pancreatic acini system in order to obtain reproducible results in repeated secretagogue stimulation. No signs of tachyphylaxis were observed when cholecystokinin-8 (CCK-8) was administered as short pulse for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b5dc072e525d77b2a8c274cceaec854a
https://pubmed.ncbi.nlm.nih.gov/11246987
https://pubmed.ncbi.nlm.nih.gov/11246987
Autor:
T, Koshiba, R, Hosotani, Y, Miyamoto, J, Ida, S, Tsuji, S, Nakajima, M, Kawaguchi, H, Kobayashi, R, Doi, T, Hori, N, Fujii, M, Imamura
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(9)
To examine the expression of the stromal cell-derived factor 1 (SDF-1)/CXCR4 receptor ligand system in pancreatic cancer cells and endothelial cells, we performed immunohistochemical analysis for 52 pancreatic cancer tissue samples with anti-CXCR4 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::76a9da1f33779f1345f7cf47978269e6
https://pubmed.ncbi.nlm.nih.gov/10999740
https://pubmed.ncbi.nlm.nih.gov/10999740
Publikováno v:
Digestive diseases and sciences. 43(11)
The preoperative determination of the localization of a small insulinoma is sometimes difficult using routine imaging techniques. We have used the selective arterial calcium injection (SACI) test to determine the location of the tumor preoperatively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6492682a4aa062242ce55e06af5d1712
https://pubmed.ncbi.nlm.nih.gov/9824130
https://pubmed.ncbi.nlm.nih.gov/9824130
Autor:
M, Wada, R, Hosotani, J U, Lee, R, Doi, T, Koshiba, K, Fujimoto, Y, Miyamoto, S, Tsuji, S, Nakajima, A, Okuyama, M, Imamura
Publikováno v:
Anticancer research. 18(4A)
We investigated the effects of an exogenous cdk inhibitor, butyrolactone-I, on cell growth inhibition, apoptosis induction, and the regulation of apoptosis in pancreatic cancer cells with mutated p53. Cell growth was dose-dependently inhibited by But
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4c5a5e19c14b5467d6fec40572ce8f4b
https://pubmed.ncbi.nlm.nih.gov/9703910
https://pubmed.ncbi.nlm.nih.gov/9703910
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(4)
One major therapeutic failure of pancreatic adenocarcinoma treatment is metastasis to the liver. To screen patients with high risk for such hematogenous dissemination, we previously developed a very sensitive system to detect carcinoembryonic antigen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b4e671999e2204635e66d861ddfe25bc
https://pubmed.ncbi.nlm.nih.gov/9563878
https://pubmed.ncbi.nlm.nih.gov/9563878
Publikováno v:
Hepato-gastroenterology. 44(18)
Surgical resection provides the only chance for long-term survival for adenocarcinoma of the pancreas. However, a major problem of surgery appears to be post-resection recurrence. The purpose of the current study was to evaluate the efficacy of intra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::abf9c07e360c08be97dbc298ba2abe41
https://pubmed.ncbi.nlm.nih.gov/9427017
https://pubmed.ncbi.nlm.nih.gov/9427017
Autor:
J U, Lee, R, Hosotani, M, Wada, R, Doi, T, Kosiba, K, Fujimoto, Y, Miyamoto, C, Mori, N, Nakamura, K, Shiota, M, Imamura
Publikováno v:
Anticancer research. 17(5A)
Cisplatin and VP-16 were used to study the induction of apoptosis in Panc-1 cells. Cisplatin and VP-16 inhibited the growth of Panc-1 cells. After 2 hours exposure to cisplatin or VP-16, attached and detached cells were subjected to TUNEL staining to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c6946dca7ec33365678f4727f6eb632a
https://pubmed.ncbi.nlm.nih.gov/9413185
https://pubmed.ncbi.nlm.nih.gov/9413185