Zobrazeno 1 - 10
of 6 097
pro vyhledávání: '"R Hoffman"'
Autor:
Ahmed Mohyeldin, Laurence J. Katznelson, Andrew R. Hoffman, Karam Asmaro, Saman S. Ahmadian, Mostafa M. Eltobgy, Jayakar V. Nayak, Zara M. Patel, Peter H. Hwang, Juan C. Fernandez-Miranda
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Recurrence and biochemical remission rates vary widely among different histological subtypes of pituitary adenoma. In this prospective study, we evaluated 107 consecutive primary pituitary adenomas operated on by a single neurosurgeon includ
Externí odkaz:
https://doaj.org/article/44503d3d0bbd4623b17cc64a72f70098
Autor:
Jacqueline R. Ho, M.D., M.S., Lusine Aghajanova, M.D., Ph.D., Evelyn Mok-Lin, M.D., Jacquelyn R. Hoffman, M.D., James F. Smith, M.D., M.Sc., Christopher N. Herndon, M.D.
Publikováno v:
F&S Reports, Vol 3, Iss 2, Pp 122-129 (2022)
Objective: To assess attitudes and factors that influence public opinion in the general US population toward insurance coverage and provision of infertility care to lower income patients. Design: Cross-sectional survey. Setting: Online. Patient(s): A
Externí odkaz:
https://doaj.org/article/2084632fe8d34b6983a7c562861c3eee
Autor:
Alexander Eng, Hillary S. Hayden, Christopher E. Pope, Mitchell J. Brittnacher, Anh T. Vo, Eli J. Weiss, Kyle R. Hager, Daniel H. Leung, Sonya L. Heltshe, Daniel Raftery, Samuel I. Miller, Lucas R. Hoffman, Elhanan Borenstein
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Infants with cystic fibrosis (CF) suffer from gastrointestinal (GI) complications, including pancreatic insufficiency and intestinal inflammation, which have been associated with impaired nutrition and growth. Recent evidence iden
Externí odkaz:
https://doaj.org/article/69900369972c4aafab8be30c1ed91e63
Autor:
Zhonghua Du, Xue Wen, Yichen Wang, Lin Jia, Shilin Zhang, Yudi Liu, Lei Zhou, Hui Li, Wang Yang, Cong Wang, Jingcheng Chen, Yajing Hao, Huiling Chen, Dan Li, Naifei Chen, Ilkay Celik, Yanbo Zhu, Zi Yan, Changhao Fu, Shanshan Liu, Benzheng Jiao, Zhuo Wang, Hui Zhang, Günhan Gülsoy, Jianjun Luo, Baoming Qin, Sujun Gao, Philipp Kapranov, Miguel A. Esteban, Songling Zhang, Wei Li, Ferhat Ay, Runsheng Chen, Andrew R. Hoffman, Jiuwei Cui, Ji-Fan Hu
Publikováno v:
Genome Biology, Vol 22, Iss 1, Pp 1-29 (2021)
Abstract Background A specific 3-dimensional intrachromosomal architecture of core stem cell factor genes is required to reprogram a somatic cell into pluripotency. As little is known about the epigenetic readers that orchestrate this architectural r
Externí odkaz:
https://doaj.org/article/2ce0442b8dc449168fea014f3b305641
Autor:
Amanda J. Morris, Lindsay Jackson, Yvonne CW Yau, Courtney Reichhardt, Trevor Beaudoin, Stephanie Uwumarenogie, Kevin M. Guttman, P. Lynne Howell, Matthew R. Parsek, Lucas R. Hoffman, Dao Nguyen, Antonio DiGiandomenico, David S. Guttman, Daniel J. Wozniak, Valerie J. Waters
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract The exopolysaccharide Psl contributes to biofilm structure and antibiotic tolerance and may play a role in the failure to eradicate Pseudomonas aeruginosa from cystic fibrosis (CF) airways. The study objective was to determine whether there
Externí odkaz:
https://doaj.org/article/e854128294d24e40bec501038888f54b
Autor:
Muthukumar Gunasekaran, Rachana Mishra, Progyaparamita Saha, David Morales, Wen-Chih Cheng, Arun R. Jayaraman, Jessica R. Hoffman, Lauran Davidson, Ling Chen, Aakash M. Shah, Gregory Bittle, Xuebin Fu, Antariksh Tulshyan, Mohamed Abdullah, Tami Kingsbury, Curt Civin, Peixin Yang, Michael E. Davis, Roberto Bolli, Joshua M. Hare, Sudhish Sharma, Sunjay Kaushal
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104656- (2022)
Summary: Successful cell therapy requires cells to resist the hostile ischemic myocardium, be retained to continue secreting cardioprotective growth factors/exosomes, and resist immunological host responses. Clinically relevant stem/progenitor cells
Externí odkaz:
https://doaj.org/article/cfa3170dcc4846bba20f01a55e64e98d
Autor:
Carlos G. Sanchez, Christopher M. Acker, Audrey Gray, Malini Varadarajan, Cheng Song, Nadire R. Cochran, Steven Paula, Alicia Lindeman, Shaojian An, Gregory McAllister, John Alford, John Reece-Hoyes, Carsten Russ, Lucas Craig, Ketthsy Capre, Christian Doherty, Gregory R. Hoffman, Sarah J. Luchansky, Manuela Polydoro, Ricardo Dolmetsch, Fiona Elwood
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Using an unbiased genome-wide CRISPR screen approach, Sanchez et al. identified modulators of endogenous tau protein. This study suggests that chromatin modifiers, neddylation, ubiquitination, and the mTOR pathways regulate overall levels of tau prot
Externí odkaz:
https://doaj.org/article/a6974f96fa3e43eca73250a0892da4a2
Autor:
Yijing Zhao, Lei Zhou, Hui Li, Tingge Sun, Xue Wen, Xueli Li, Ying Meng, Yan Li, Mengmeng Liu, Shanshan Liu, Su-Jeong Kim, Jialin Xiao, Lingyu Li, Songling Zhang, Wei Li, Pinchas Cohen, Andrew R. Hoffman, Ji-Fan Hu, Jiuwei Cui
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 23, Iss , Pp 264-276 (2021)
Mitochondrial dysfunction is a metabolic hallmark of cancer cells. In search of molecular factors involved in this dysregulation in hepatocellular carcinoma (HCC), we found that the nuclear-encoded long noncoding RNA (lncRNA) MALAT1 (metastasis-assoc
Externí odkaz:
https://doaj.org/article/c861857d405a49bba84dca50e249ee81
Publikováno v:
Cell Death and Disease, Vol 12, Iss 3, Pp 1-14 (2021)
Abstract Pseudomonas aeruginosa is a common respiratory pathogen in cystic fibrosis (CF) patients which undergoes adaptations during chronic infection towards reduced virulence, which can facilitate bacterial evasion of killing by host cells. However
Externí odkaz:
https://doaj.org/article/5a0cb35cbf96485cb605b9abdac30acb
Publikováno v:
Critical Care, Vol 25, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/ecf08dd471154facbc7dc9989e336f3b