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of 65
pro vyhledávání: '"R Hermon Dowling"'
Autor:
R Hermon Dowling, Martin J Veysey, Stephen P Pereira, S Hyder Hussaini, Linzi A Thomas, John AH Wass, Gerard M Murphy
Publikováno v:
Canadian Journal of Gastroenterology, Vol 11, Iss 1, Pp 57-64 (1997)
Increasing evidence implicates prolonged intestinal transit (slow transit constipation) in the pathogenesis of conventional gallbladder stones (GBS), and that of gallstones induced by long term octreotide (OT) treatment. Both groups of GBS patients h
Externí odkaz:
https://doaj.org/article/a24e6a3e046c4b00ac5c8a30ca8c9f32
Autor:
R. Hermon Dowling
Publikováno v:
The Journal of Nutrition. 133:3703-3707
Of the many models of intestinal adaptation, the structural and functional changes seen in the residual small bowel following jejunectomy or ileectomy are the most predictable and best studied. There are three major mechanisms for these adaptive phen
Autor:
T Bathgate, Gerard M. Murphy, R. Hermon Dowling, Nigel Smeeton, Gary French, Anna King, LA Thomas, Martin Veysey
Publikováno v:
Gastroenterology. 119:806-815
Background & Aims: Many patients with cholesterol gallbladder stones (GBS) have a high percentage of deoxycholic acid (DCA) in gallbladder bile (all of which are in the conjugated form), probably as a result of prolonged large bowel transit times (LB
Publikováno v:
Journal of Hepatology. 32:4-10
The development of cholesterol gallstones, in some patients, has been associated with increased proportions of deoxycholic acid in the bile acid pool. Deoxycholic acid is a microbial product of cholic acid 7alpha-dehydroxylation in the intestines. Th
Publikováno v:
Hepatology. 22:1735-1744
Little is known about the effects of biliary deoxycholic acid on the partitioning of biliary cholesterol between vesicles and micelles and on the rate of nucleation of cholesterol microcrystals, key steps in gallstone formation. Therefore, 43 samples
Publikováno v:
Current Opinion in Gastroenterology. 9:800-809
Autor:
W. John Albery, Gerard M. Murphy, Girish Rao, Edmond Magner, David Armstrong, R. Bruce Lennox, R. Hermon Dowling
Publikováno v:
Analytica Chimica Acta. 281:655-661
An amperometric enzyme electrode for the detection of bile acids using 3-α-hydroxysteroid dehydrogenase coupled to an N -methyl phenazinium tetracyanoquinodimethanide electrode (NMPTCNQ) is described. Kinetic analysis shows that the rate limiting st
Autor:
Anthony Mallet, Martin Veysey, Gerard M. Murphy, Paul J. Jenkins, LA Thomas, G. Michael Besser, R. Hermon Dowling
Publikováno v:
Gastroenterology. 121(4)
Prolonged large bowel transit, and an increase in the proportion of deoxycholic acid (DCA), have been implicated in the pathogenesis of cholesterol gallstones-including those developing in acromegalics treated with octreotide. However, there are few
Influence of pH on the phase distribution of nascent deoxycholic acid in fresh human cecal aspirates
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 281(2)
Prolonged large bowel transit time and an associated increase in the proportion of deoxycholic acid (DCA) in serum and bile have been implicated in the development of cholesterol-rich gallstones and colon cancer. Prolongation of intestinal transit al
Autor:
R. Hermon Dowling
Publikováno v:
Acta Médica Portuguesa, Vol 4, Iss 1 (1983)
UDCA was introduced as a gallstone dissolving agent some 5 years after COCA. Experience with urso is, therefore, more limited but the initial 5-7 years of clinical investigation for CDCA have been condensed into a mere 1-2 years for UDCA. As a result
Externí odkaz:
https://doaj.org/article/f16d2d70dae74056b3eccea8b3e6aaee