Zobrazeno 1 - 10
of 537
pro vyhledávání: '"R Heaton"'
Autor:
Anna Hoefges, Paul M Sondel, Alexander L Rakhmilevich, Arika S Feils, Alina A Hampton, Noah W Tsarovsky, Amy K Erbe-Gurel, Alexa R Heaton, Nathaniel J Burkard, Garrett M Lublin, Melissa C Skala
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/4974d29cc9e9470d91ac46ce206f9c5d
Autor:
Alexa R. Heaton, Peter R. Rehani, Anna Hoefges, Angelica F. Lopez, Amy K. Erbe, Paul M. Sondel, Melissa C. Skala
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionMetabolic reprogramming of cancer and immune cells occurs during tumorigenesis and has a significant impact on cancer progression. Unfortunately, current techniques to measure tumor and immune cell metabolism require sample destruction an
Externí odkaz:
https://doaj.org/article/c2c82cf09a1d44eca7d13b82746ddc1c
Autor:
Kenneth Gavina, Lauren C. Franco, Christopher M. Robinson, Weston Hymas, Guang-Sheng Lei, Will Sinclair, Tara Hall, John Carlquist, John-Paul Lavik, Christopher L. Emery, Phillip R. Heaton, David Hillyard, Bert K. Lopransi, Ryan F. Relich
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The demand for testing during the coronavirus disease 2019 (COVID-19) pandemic has resulted in the production of several different commercial platforms and laboratory-developed assays for the detection of severe acute respiratory syndrome co
Externí odkaz:
https://doaj.org/article/caf803cdbd0d4ab49b0813ed502e2a99
Autor:
Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Kirsten Harvey, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson
Publikováno v:
PLoS Biology, Vol 20, Iss 5, p e3001621 (2022)
[This corrects the article DOI: 10.1371/journal.pbio.3001480.].
Externí odkaz:
https://doaj.org/article/0cfb6188812b44e8a7612e5d6a062027
Autor:
Adamantios Mamais, Jillian H Kluss, Luis Bonet-Ponce, Natalie Landeck, Rebekah G Langston, Nathan Smith, Alexandra Beilina, Alice Kaganovich, Manik C Ghosh, Laura Pellegrini, Ravindran Kumaran, Ioannis Papazoglou, George R Heaton, Rina Bandopadhyay, Nunziata Maio, Changyoun Kim, Matthew J LaVoie, David C Gershlick, Mark R Cookson
Publikováno v:
PLoS Biology, Vol 19, Iss 12, p e3001480 (2021)
Mutations in leucine-rich repeat kinase 2 (LRRK2) cause autosomal dominant Parkinson disease (PD), while polymorphic LRRK2 variants are associated with sporadic PD. PD-linked mutations increase LRRK2 kinase activity and induce neurotoxicity in vitro
Externí odkaz:
https://doaj.org/article/71c689db45394c029f869d5ffc9ae238
Publikováno v:
Molecular Neurodegeneration, Vol 14, Iss 1, Pp 1-22 (2019)
Abstract Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central to the aetiology of Parkinson’s disease, a considerable amount of work has gone into uncovering its basic cellular function. This effort has le
Externí odkaz:
https://doaj.org/article/c4616cd1e02543e2a8eb9ea9428130f5
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
Macrophages are dynamic immune cells that govern both normal tissue function and disease progression. However, standard methods to measure heterogeneity in macrophage function within tissues require tissue excision and fixation, which limits our unde
Externí odkaz:
https://doaj.org/article/ac1d5bfba83444b59c66020bd63e0ce6
Autor:
George R. Heaton, Natalie Landeck, Adamantios Mamais, Mike A. Nalls, Jonathon Nixon-Abell, Ravindran Kumaran, Alexandra Beilina, Laura Pellegrini, Yan Li, Kirsten Harvey, Mark R. Cookson
Publikováno v:
Neurobiology of Disease, Vol 141, Iss , Pp 104948- (2020)
Mutations in leucine-rich repeat kinase 2 (LRRK2) are an established cause of inherited Parkinson's disease (PD). LRRK2 is expressed in both neurons and glia in the central nervous system, but its physiological function(s) in each of these cell types
Externí odkaz:
https://doaj.org/article/269f392a74f74455bdede54a390324cd
Autor:
Steven P. Seegobin, George R. Heaton, Dongxiao Liang, Insup Choi, Marian Blanca Ramirez, Beisha Tang, Zhenyu Yue
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene are the most frequent cause of familial Parkinson’s disease (PD). Several genetic manipulations of the LRRK2 gene have been developed in animal models such as rodents, Drosophila, Caenorhab
Externí odkaz:
https://doaj.org/article/38e045d38be449f1b3602c2512114536
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.