Výsledky vyhledávání - "R H H, Neubert"

[Development of an ivermectin-containing syrup as an extemporaneous preparation for treatment of scabies in children]

Autor: Johannes, Wohlrab, L, Stadie, R H H, Neubert, K, Bosse

Publikováno v: Der Hautarzt; Zeitschrift Fur Dermatologie, Venerologie, Und Verwandte Gebiete

Oral ivermectin can be used to treat scabies. Evidence for safe and effective use in young children in individual treatment situations has been developed and published. In order to also ensure a body weight-adapted dosage for children, an ivermectin-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::79be49fc53fc8cf702e691d41b6c86e9
https://pubmed.ncbi.nlm.nih.gov/33847760

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Assessment of the applicability of HLB values for natural phospholipid emulsifiers for preparation of stable emulsions

Autor: F, Otto, P, van Hoogevest, F, Syrowatka, V, Heinl, R H H, Neubert

Publikováno v: Die Pharmazie. 75(8)

Natural phospholipid (PL) excipients are native, biocompatible and relatively inexpensive alternatives to synthetic emulsifiers. A well-known PL excipient is lecithin, which primarily contains phosphatidylcholine (PC) and (depending on the purity gra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e282b290b167ad84b91c4a5c29b57fa2
https://pubmed.ncbi.nlm.nih.gov/32758334

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Studies of the Corneocytary Pathway Across the Stratum Corneum. Part I: Diffusion of Amino Acids Into the Isolated Corneocytes

Autor: H, Hussain, J, Ziegler, Y, Mrestani, R H H, Neubert

Publikováno v: Die Pharmazie. 74(6)

Amino acids (AAs), important constituents of natural moisturizing factors (NMFs) of the skin are decreased in diseased conditions such as psoriasis and atopic dermatitis. No study so far investigated the uptake of AAs into isolated corneocytes (COR).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fdbc88b03f5194f94845b828a649cf6e
https://pubmed.ncbi.nlm.nih.gov/31138370

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Dermal peptide delivery using enhancer molecules and colloidal carrier systems - part V

Autor: A, Foerster, R H H, Neubert

Publikováno v: Die Pharmazie. 74(3)

In a previous study, it was shown, that shed snake skin is a good alternative model membrane for the human stratum corneum (SC). In this study, the influence of the enhancers dimethyl sulfoxide (DMSO), 1,2-propanediol, 1,3-butanediol, 1,2-pentanediol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::adea6980664982a41980b20ec9acf4ef
https://pubmed.ncbi.nlm.nih.gov/30961677

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Effect of hyaluronic acid initial concentration on cross-linking efficiency of hyaluronic acid - based hydrogels used in biomedical and cosmetic applications

Autor: M, Al-Sibani, A, Al-Harrasi, R H H, Neubert

Publikováno v: Die Pharmazie. 72(2)

This work was aimed to explore the potential effect of hyaluronic acid (HA) initial concentration (7.0 - 14.0 % w/v) on cross-linking efficiency of HA hydrogels cross-linked with 1,4-butanediol diglycidyl ether (BDDE). The results revealed that the h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::664f23145951bbc6ad9de4c9b2aae471
https://pubmed.ncbi.nlm.nih.gov/29441857

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Retarder action of isosorbide in a microemulsion for a targeted delivery of ceramide NP into the

Autor: S C, Steinbach, R, Triani, L, Bennedsen, A, Gabel, O, Haeusler, J, Wohlrab, R H H, Neubert

Publikováno v: Die Pharmazie. 72(8)

Ceramide [NP] is an integral component of the stratum corneum (SC) lipid matrix and is capable of forming tough and stable lamellar structures. It was proven, that in skin diseases as psoriasis or atopic dermatitis different ceramide (CER) classes, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8fec62ce5eeaacc3f8b7fa63048eefd7
https://pubmed.ncbi.nlm.nih.gov/29441901

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[Clotrimazole and ciclopirox olamine respectively in combination with methylprednisolone aceponate as extemporaneous formulations]

Autor: J, Wohlrab, R H H, Neubert, E, Sommer, J, Michael

Publikováno v: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 68(4)

The combination of topical fungicide and glucocorticoids has been proven as a successful therapy of cutaneous mycoses with accompanying inflammatory reactions, particularly when used at an early stage. Various national and international therapeutic g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6feb2fa6ec2d5a2d784657309237904c
https://pubmed.ncbi.nlm.nih.gov/28091698

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Investigation in W/O developed microemulsions with DMSO as a cosurfactant

Autor: J Alyoussef, Alkrad, A, Shukla, Y, Mrestani, R H H, Neubert

Publikováno v: Die Pharmazie. 71(5)

In this study the effect of dimethylsulfoxide (DMSO) radii on the droplets and on the required non-ionic surfactant volume for preparing water-in-oil microemulsions (MEs) was investigated. Five series of MEs were prepared either with the aid of isopr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::c592d36d927331a87811bf8002bfc4fe
https://pubmed.ncbi.nlm.nih.gov/27348969

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Properties of Ceramides and Their Impact on the Stratum Corneum Structure: A Review

Autor: R H H Neubert, S Wartewig

Publikováno v: Skin Pharmacology and Physiology. 20:220-229

The lipid matrix of the stratum corneum (SC) is the major diffusion-rate-limiting pathway by which most drugs intracellularly pass the SC. The major lipid classes extracted from the SC are ceramides, cholesterol and free fatty acids. Ceramides that c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3cc86a8df84c2057af61b82003796ba9
https://doi.org/10.1159/000104420

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