Zobrazeno 1 - 10
of 66
pro vyhledávání: '"R H Buckley"'
Autor:
M L Markert, D D Kostyu, F E Ward, T M McLaughlin, T J Watson, R H Buckley, S E Schiff, R M Ungerleider, J W Gaynor, K T Oldham, S M Mahaffey, M Ballow, D A Driscoll, L P Hale, B F Haynes
Publikováno v:
The Journal of Immunology. 158:998-1005
Transplantation of cultured postnatal human thymus was performed in a patient with complete DiGeorge syndrome. Biopsy of the graft 3 mo after implantation revealed normal CD1+ thymocytes in thymic cortical epithelial regions and CD1- thymocytes in th
Autor:
R. H. Buckley
Publikováno v:
JAMA: The Journal of the American Medical Association. 268:2797-2806
Publikováno v:
The Journal of Immunology. 144:2123-2130
Unfractionated human blood mononuclear cells (MNC) from normal and atopic donors cultured in enriched Iscove's modified Dulbecco's medium supplemented with 10% FCS responded similarly to stimulation with purified human rIL-4 (rhIL-4) with respect to
Autor:
Y J, Zhou, M, Chen, N A, Cusack, L H, Kimmel, K S, Magnuson, J G, Boyd, W, Lin, J L, Roberts, A, Lengi, R H, Buckley, R L, Geahlen, F, Candotti, M, Gadina, P S, Changelian, J J, O'Shea
Publikováno v:
Molecular cell. 8(5)
Janus kinases comprise carboxyterminal kinase, pseudokinase, SH2-like, and N-terminal FERM domains. We identified three patient-derived mutations in the FERM domain of Jak3 and investigated the functional consequences of these mutations. These mutati
Publikováno v:
Blood. 92(7)
CD40 is a member of the tumor necrosis factor receptor family and plays an important role in B-cell survival, growth, differentiation, and isotype switching. Recently, CD40 has been shown to associate with JAK3, a member of the family of Janus Kinase
Publikováno v:
Journal of clinical immunology. 17(4)
The origin of natural antibodies has long been a subject of controversy. Polyreactive natural antibodies recognize multiple ligands and are thought to arise from B1 B cells. Natural antibodies against carbohydrate antigens such as Gal alpha 1-3Gal or
Autor:
J M, Puck, A E, Pepper, P S, Henthorn, F, Candotti, J, Isakov, T, Whitwam, M E, Conley, R E, Fischer, H M, Rosenblatt, T N, Small, R H, Buckley
Publikováno v:
Blood. 89(6)
Severe combined immunodeficiency (SCID) is a syndrome of profoundly impaired cellular and humoral immunity. In humans, SCID is most commonly caused by mutations in the X-linked gene IL2RG, which encodes the common gamma chain, gamma c, of the leukocy
Autor:
C M, Davis, T M, McLaughlin, T J, Watson, R H, Buckley, S E, Schiff, L P, Hale, B F, Haynes, M L, Markert
Publikováno v:
Journal of clinical immunology. 17(2)
Complete DiGeorge syndrome is an immunodeficiency disease characterized by thymic aplasia and the absence of functioning peripheral T cells. A patient with this syndrome was transplanted with cultured postnatal human thymic tissue. Within 5 weeks of
Autor:
M L, Markert, D D, Kostyu, F E, Ward, T M, McLaughlin, T J, Watson, R H, Buckley, S E, Schiff, R M, Ungerleider, J W, Gaynor, K T, Oldham, S M, Mahaffey, M, Ballow, D A, Driscoll, L P, Hale, B F, Haynes
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(2)
Transplantation of cultured postnatal human thymus was performed in a patient with complete DiGeorge syndrome. Biopsy of the graft 3 mo after implantation revealed normal CD1+ thymocytes in thymic cortical epithelial regions and CD1- thymocytes in th
Publikováno v:
Journal of clinical immunology. 17(1)
The safety and clinical efficacy of a liquid, beta-propiolactone-stabilized intravenous gamma-globulin, Intraglobin-F, was evaluated in a multicenter, double-blind study comparing Intraglobin-F to Gamimune-N, Sandoglobulin, or Gammagard. beta-Propiol