Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R H, Snider"'
Publikováno v:
Journal of Endotoxin Research. 9:367-374
Prior studies have demonstrated that the prohormone, procalcitonin (ProCT), and its component calcitonin precursors (CTpr) are increased in the serum of septic patients, correlate with the severity of the illness, and persist for relatively long peri
Autor:
Jon White, Kenneth L. Becker, R. H. Snider, M. J. McMahon, Eric S. Nylen, G R Barclay, Basil J. Ammori, Peter Kite, Michael Larvin
Publikováno v:
Pancreas. 27:239-243
Severe acute pancreatitis is associated with an early increase in intestinal permeability and endotoxemia. Endotoxin is a potent stimulator for the production and release of procalcitonin and its components (calcitonin precursors; [CTpr]). The aim of
Autor:
Paul M. Yen, M. Stene, Nicholas J. Sarlis, K. L. Becker, R. H. Snider, Gabriel I. Uwaifo, Alan T. Remaley, James C. Reynolds
Publikováno v:
Journal of Endocrinological Investigation. 24:361-369
The measurement of plasma CT has an important role as a screening test for medullary thyroid carcinoma (MTC) in patients with thyroid nodules. However, elevated plasma CT levels should be interpreted within the context of the overall clinical picture
Autor:
K T, Whang, S D, Vath, K L, Becker, R H, Snider, E S, Nylen, B, Muller, Q, Li, L, Tamarkin, J C, White
Publikováno v:
Shock. 12:268-273
Immunoneutralization of procalcitonin (ProCT), a putative mediator of sepsis, has been shown to increase survival in an animal model of sepsis. To better understand the role that ProCT plays in the sepsis cascade, we studied the relationship of this
Autor:
Eric S. Nylen, James C. Jeng, M.S. Lewis, K. A. Thompson, W. O'Neill, M. H. Jordan, K.L. Becker, R. H. Snider
Publikováno v:
Respiratory Medicine. 89(1):41-46
Seven patients were evaluated at a mean duration of 8·4 yr after sustaining inhalational injury associated with burns. At the time of re-examination, the patients were asymptomatic and had normal chest X-rays, and arterial blood gases. Three of the
Autor:
O. L. Silva, Eric S. Nylen, M. H. Jordan, Kenneth L. Becker, C. F. Moore, R. H. Snider, W. O'Neill, M.S. Lewis
Publikováno v:
Hormone and Metabolic Research. 24:439-442
The molecular heterogeneity of serum immunoreactive calcitonin (iCT) was analyzed from a prospective study of 41 burn patients. Using different region-specific anticalcitonin antisera, the ratio of mid-region-recognizing to carboxyl terminal-region-r
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(1)
Calcitonin precursors (CTpr), including procalcitonin, are important markers and also potentially harmful mediators in response to microbial infections. The source and function of CTpr production in sepsis, however, remains an enigma. In the classica
Autor:
B, Müller, K L, Becker, M, Kränzlin, H, Schächinger, P R, Huber, E S, Nylèn, R H, Snider, J C, White, H, Schmidt-Gayk, W, Zimmerli, R, Ritz
Publikováno v:
European journal of clinical investigation. 30(9)
Hypocalcemia and increased serum levels of calcitonin precursors are common in critically ill patients, especially in those with sepsis. We investigated calcium homeostasis in such patients.Serum concentrations of total and ionized calcium and known
Autor:
K T, Whang, P M, Steinwald, J C, White, E S, Nylen, R H, Snider, G L, Simon, R L, Goldberg, K L, Becker
Publikováno v:
The Journal of clinical endocrinology and metabolism. 83(9)
High serum levels of the calcitonin (CT) prohormone, procalcitonin (pro-CT), and its component peptides occur in systemic inflammation and sepsis. Using two different assays, we undertook a prospective study to determine the utility of serum precalci
Publikováno v:
Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 45(9)
The systemic inflammatory response syndrome (SIRS) is a marked, generalized response to a variety of injuries, if infection is implicated, the term "sepsis" is used. Systemic inflammatory response syndrome/sepsis, which is initiated by proinflammator