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EVALUATION OF THE EFFICACY, SAFETY, AND TOLERABILITY OF EZETIMIBE IN PRIMARY HYPERCHOLESTEROLAEMIA: A POOLED ANALYSIS FROM TWO CONTROLLED PHASE III CLINICAL STUDIES

Autor: R H, Knopp, C A, Dujovne, A, Le Beaut, L J, Lipka, R, Suresh, E P, Veltri

Publikováno v: International Journal of Clinical Practice. 57:363-368

Ezetimibe is a novel cholesterol absorption inhibitor that blocks intestinal absorption of dietary and biliary cholesterol. Data from 1719 patients who participated in two multicentre, double-blind studies of ezetimibe were pooled to evaluate the dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf7c2218e355db389a07cd0701343514
https://doi.org/10.1111/j.1742-1241.2003.tb10508.x

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Dietary Guidelines for Healthy American Adults

Autor: T. E. Prewitt, Thomas A. Pearson, Richard J. Deckelbaum, Ronald M. Krauss, R. H. Knopp, T. Kotchen, R. Weinberg, L. Van Horn, Barbara V. Howard, Nancy D. Ernst, Alice H. Lichtenstein, Edward A. Fisher, H. C. Mcgill, Neil J. Stone

Publikováno v: Circulation. 94:1795-1800

In 1957 the American Heart Association proposed that modification of dietary fat intake would reduce the incidence of coronary heart disease (CHD), which had become the leading cause of disability and death in the United States and other industrializ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d0b59f1a3e2e9590e4eb766aa38419c
https://doi.org/10.1161/01.cir.94.7.1795

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Deformations in infants of diabetic and control pregnancies

Autor: M I Van Allen, R. H. Knopp, B. Plovie, M. L. Hanson, Z. A. Brown

Publikováno v: American Journal of Medical Genetics. 53:210-215

Severe and mild deformations in newborn infants of insulin dependent diabetic mothers (IDDMs) and control mothers were evaluated with respect to the types of anomalies and previously hypothesized constraint factors. Factors evaluated were gestational

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::866ab0bff317d7d219b4d965aae3e661
https://doi.org/10.1002/ajmg.1320530303

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The benefits of statins in people without established cardiovascular disease but with cardiovascular risk factors: meta-analysis of randomised controlled trials

Autor: Tuncay Yetgin, A.J.M. de Craen, Sanne E. Hoeks, R. H. Knopp, Paul M. Ridker, Rudi G. J. Westendorp, R. Van Domburg, Antonio M. Gotto, J. Shepherd, Jasper J. Brugts, Jaap W. Deckers, Haruo Nakamura

Publikováno v: British Medical Journal, 339. BMJ Publishing Group
The BMJ

Objectives To investigate whether statins reduce all cause mortality and major coronary and cerebrovascular events in people without established cardiovascular disease but with cardiovascular risk factors, and whether these effects are similar in men

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::153b8f57768654d20e7546627f88e6da
https://doi.org/10.1136/bmj.b2376

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Estimating low-density lipoprotein cholesterol by the Friedewald equation is adequate for classifying patients on the basis of nationally recommended cutpoints

Autor: L Branson, G R Warnick, R H Knopp, V Fitzpatrick

Publikováno v: Clinical Chemistry. 36:15-19

We compared low-density lipoprotein cholesterol (LDL) values obtained by the Friedewald formula--i.e., total cholesterol minus high-density lipoprotein (HDL) cholesterol minus very-low-density lipoprotein (VLDL) cholesterol (estimated as triglyceride

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee817f00018e4ecbaf4eb7823e10d1a1
https://doi.org/10.1093/clinchem/36.1.15

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Plasma pancreatic polypeptide levels are associated with differences in body fat distribution in human subjects

Autor: R. H. Knopp, Steven E. Kahn, K. M. Utzschneider, J. Tong, F. Gerchman, J. Udayasankar, Daniel B. Carr, S. Zraika

Publikováno v: Diabetologia. 50(2)

Pancreatic polypeptide (PP) is produced by the F-cells of the pancreas, and its plasma concentration has been used as a marker of parasympathetic activity. Recent work in rodents suggests that there is both sympathetic and parasympathetic innervation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a0d7885c63023183b4c8a31f33a5c7
https://pubmed.ncbi.nlm.nih.gov/17171555

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Extended-release niacin vs gemfibrozil for the treatment of low levels of high-density lipoprotein cholesterol. Niaspan-Gemfibrozil Study Group

Autor: J R, Guyton, M A, Blazing, J, Hagar, M L, Kashyap, R H, Knopp, J M, McKenney, D T, Nash, S D, Nash

Publikováno v: Archives of internal medicine. 160(8)

To provide a direct comparison of agents that raise plasma levels of high-density lipoprotein cholesterol (HDL-C) to help devise strategies for coronary risk reduction.In a multicenter, randomized, double-blind trial, we compared the effects of exten

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7b9b3c9f2bc0d2c270c8fef1e1b31ff9
https://pubmed.ncbi.nlm.nih.gov/10789612

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Coronary heart disease moderates the relationship of chronic stress with the metabolic syndrome

Autor: P P, Vitaliano, J M, Scanlan, I C, Siegler, W C, McCormick, R H, Knopp

Publikováno v: Health psychology : official journal of the Division of Health Psychology, American Psychological Association. 17(6)

Metabolic syndrome levels (MSLs) were compared in caregivers (CGs) of spouses with Alzheimer's disease who had diagnoses of coronary heart disease (CHD; n = 27) with non CGs with CHD diagnoses (n = 18), and CGs (n = 44) to non CGs (n = 52) free of CH

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::d97f50c22d81af7dfa5f44f565712a65
https://pubmed.ncbi.nlm.nih.gov/9848802

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