Zobrazeno 1 - 5
of 5
pro vyhledávání: '"R H, Gruninger"'
Autor:
S. A. Middleton, W. H. Lee, F. J. McMahon, L. S. Mulcahy, Dana L. Johnson, Linda K. Jolliffe, F. P. Barbone, R. H. Gruninger
Publikováno v:
Nephrology Dialysis Transplantation. 10:28-34
Erythropoietin (EPO) is the primary hormone responsible for the growth and maturation of red blood cells in mammals. In contrast to many other growth factors, the specificity of EPO for mature erythroid cells has lead to its development as a safe and
Autor:
J P Boissel, J. Czelusniak, T. E. Tracy, R. H. Gruninger, Danyi Wen, L. S. Mulcahy, H F Bunn, Michael J. Goodman
Publikováno v:
Blood. 82:1507-1516
To investigate structure-function relationships of erythropoietin (Epo), we have obtained cDNA sequences that encode the mature Epo protein of a variety of mammals. A first set of primers, corresponding to conserved nucleotide sequences between mouse
Autor:
F P, Barbone, S A, Middleton, D L, Johnson, F J, McMahon, J, Tullai, R H, Gruninger, A E, Schilling, L K, Jolliffe, L S, Mulcahy
Publikováno v:
The Journal of biological chemistry. 272(8)
Mutagenesis of the erythropoietin receptor (EPOR) permits analysis of the contribution that individual amino acid residues make to erythropoietin (EPO) binding. We employed both random and site-specific mutagenesis to determine the function of amino
Autor:
S A, Middleton, D L, Johnson, R, Jin, F J, McMahon, A, Collins, J, Tullai, R H, Gruninger, L K, Jolliffe, L S, Mulcahy
Publikováno v:
The Journal of biological chemistry. 271(24)
The erythropoietin receptor (EPOR) is a member of a family of cytokine and growth factor receptors that share conserved features in their extracellular and cytoplasmic domains. We have used site-specific mutagenesis within the extracellular domain of
Autor:
L K, Jolliffe, S A, Middleton, F P, Barbone, D L, Johnson, F J, McMahon, W H, Lee, R H, Gruninger, L S, Mulcahy
Publikováno v:
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association. 10
Erythropoietin (EPO) is the primary hormone responsible for the growth and maturation of red blood cells in mammals. In contrast to many other growth factors, the specificity of EPO for mature erythroid cells has lead to its development as a safe and