Zobrazeno 1 - 10
of 48
pro vyhledávání: '"R H, Gelber"'
Autor:
Vijaykumar Pannikar, Paul Saunderson, Eduardo C. Dela Cruz, R. H. Gelber, Kyaw Kyaw, Teky Budiawan, Esterlina V. Tan, Victoria F. Balagon, Masanori Matsuoka, Khin Saw Aye
Publikováno v:
Leprosy Review. 78:343-352
Introduction The magnitude of drug resistance in Mycobacterium leprae to dapsone, rifampicin, and ofloxacin was studied in three Southeast Asian countries with a high prevalence of leprosy. Methods M. leprae from the skin of leprosy patients was coll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f054ddd60a62976dfc0e8e683cc78d4b
https://doi.org/10.47276/lr.78.4.343
https://doi.org/10.47276/lr.78.4.343
Autor:
R. H. Gelber
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 13:942-952
Leprosy is a major debilitating infectious disease, primarily of the developing world. In this paper the current status and future prospects of antimicrobial therapy of the severe anergic lepromatous form of the disease are reviewed. Until the last f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b976c5bd719839f09615f483d5b60504
https://doi.org/10.1007/bf02111496
https://doi.org/10.1007/bf02111496
Publikováno v:
Infection and Immunity. 62:4250-4255
In this study, we evaluated vaccination with a number of purified, as well as recombinant, Mycobacterium leprae proteins for protective efficacy in mice. BALB/c mice were immunized intradermally with various native somatic (purified) or recombinant M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab0b82832eb346a30184c6966f30eb7f
https://doi.org/10.1128/iai.62.10.4250-4255.1994
https://doi.org/10.1128/iai.62.10.4250-4255.1994
Publikováno v:
Antimicrobial Agents and Chemotherapy. 36:2544-2547
Previously, pefloxacin and ofloxacin were found to be active against Mycobacterium leprae in vitro, in experimental animals, and in clinical trials of lepromatous leprosy patients. In this study, we compared certain more recently developed fluoroquin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::822ad4528570f30517546b1d0261f05a
https://doi.org/10.1128/aac.36.11.2544
https://doi.org/10.1128/aac.36.11.2544
Publikováno v:
Infection and Immunity. 58:703-710
Despite the recent identification of a number of Mycobacterium leprae proteins, the major immunogenic determinants of this organism remain obscure. We isolated from M. leprae a potent immunostimulatory preparation, designated the MLP fraction, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::871a50cdfd204806090e67e17d59e2b6
https://doi.org/10.1128/iai.58.3.703-710.1990
https://doi.org/10.1128/iai.58.3.703-710.1990
Autor:
Patrick J. Brennan, P Siu, M Tsang, J M Monson, Edgar G. Engleman, L P Murray, N Mohagheghpour, M W Munn, R. H. Gelber, S W Hunter
Publikováno v:
Infection and Immunity. 58:711-718
Model vaccines against leprosy bacilli have consisted of nonvirulent, live, attenuated Mycobacterium bovis BCG and irradiated, heat-killed, or autoclaved intact M. leprae. We report that immunization with various cell wall fractions of M. leprae, pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf235c9ebc0c3fffca7d1072bef3f5a
https://doi.org/10.1128/iai.58.3.711-718.1990
https://doi.org/10.1128/iai.58.3.711-718.1990
Publikováno v:
Archives of Dermatology. 126:1584-1586
We found that in the years 1978 through 1981 only one of 54 previously untreated patients with Hansen's disease was found to harbor dapsone-resistant Mycobacterium leprae. That single strain was only partially resistant, ie, it was resistant to 0.000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e350abb34476fe7493670eee1042cb96
https://doi.org/10.1001/archderm.126.12.1584
https://doi.org/10.1001/archderm.126.12.1584
Autor:
R H Gelber
Fifty patients with newly diagnosed lepromatous leprosy were allocated randomly to one of five groups and treated with either a month-long standard regimen of multidrug therapy (MDT) for multibacillary leprosy, a single dose of 600 mg of rifampin, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4934c657e57db479f0c6d3ec5227f517
https://europepmc.org/articles/PMC163974/
https://europepmc.org/articles/PMC163974/
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 63(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::87096ecef5edfa426be55f7e41fd1fbc
https://pubmed.ncbi.nlm.nih.gov/7602228
https://pubmed.ncbi.nlm.nih.gov/7602228
Publikováno v:
International journal of leprosy and other mycobacterial diseases : official organ of the International Leprosy Association. 63(2)
In these studies we evaluated the activity of low levels of five antimicrobials against Mycobacterium leprae-infected mice when administered singly and in all possible two- and three-drug combinations. Antibiotics studied were: dapsone (D) 0.0001% in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f040e35dc639168cbddf0dd6715d8947
https://pubmed.ncbi.nlm.nih.gov/7602221
https://pubmed.ncbi.nlm.nih.gov/7602221