Zobrazeno 1 - 4
of 4
pro vyhledávání: '"R H, Dewey"'
Autor:
J F, Newton, K M, Straub, R H, Dewey, C D, Perchonock, M E, McCarthy, J G, Gleason, R K, Lynn
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 20(4)
A primary route of inactivation of leukotrienes and their receptor antagonists (LTRA) is metabolism by omega oxidation. SKF 102922 [5-(2-(8-phenyloctyl)phenyl)-4,6-dithianonanedioic acid] is a LTRA that was designed to be resistant to omega oxidation
Autor:
A P, Intoccia, T L, Flanagan, D T, Walz, L, Gutzait, J E, Swagzdis, J, Flagiello, B Y, Hwang, R H, Dewey, H, Noguchi
Publikováno v:
The Journal of rheumatology. Supplement. 8
Gold from orally administered auranofin (AF) was absorbed 17-23% in rats and 15-38% in dogs. Gold was highly bound to blood cells and plasma proteins. Gold terminal half life was 1.2-1.8 days in rat blood and plasma (measured for 7 days post dose) an
Autor:
J F, Newton, K M, Straub, R H, Dewey, C D, Perchonock, T B, Leonard, M E, McCarthy, J G, Gleason, R D, Eckardt
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 15(2)
In vivo experiments indicate that the major route of metabolism of SKF 102,081 [5-(2-dodecylphenyl)-4,6-dithianonanedioic acid] is via omega-oxidation and subsequent beta-oxidation. Therefore, in vitro experiments were designed to characterize the in
Autor:
R. H. Dewey, W. K. Anderson
Publikováno v:
Chemischer Informationsdienst. 8