Zobrazeno 1 - 10
of 18
pro vyhledávání: '"R H, Bassin"'
Publikováno v:
Molecular and Cellular Biology. 12:3750-3756
Using an expression cloning assay, we have isolated a novel cDNA, referred to as rsp-1, which suppresses the v-Ras-transformed phenotype. When introduced into NIH 3T3 fibroblasts under the control of a metallothionein promoter, rsp-1 confers resistan
Publikováno v:
Modern Trends in Human Leukemia IX ISBN: 9783540543602
Studies of oncogenes have established that their cellular homologs are part of a kinase cascade mechanism that regulates the translation of exogenous growth factor stimulation into a mitogenic gene response [reviewed in 1]. The cellular homolog of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7145ce8b49ec9f93c5d8ec687ef89470
https://doi.org/10.1007/978-3-642-76829-3_33
https://doi.org/10.1007/978-3-642-76829-3_33
Publikováno v:
Cancer research. 51(1)
The hypomethylating chemotherapeutic drug 5-aza-2'-deoxycytidine (5AzadC) has been shown to induce cell differentiation in some systems, while promoting neoplastic transformation in others. Using both in vitro and in vivo models, we have explored the
Autor:
B, Blondel, N, Talbot, G R, Merlo, C, Wychowski, H, Yokozaki, E M, Valverius, D S, Salomon, R H, Bassin
Publikováno v:
Oncogene. 5(6)
In both experimental and spontaneous tumors, c-myc expression is often enhanced following its amplification or its rearrangement adjacent to a strong promotor/enhancer. However, c-myc by itself does not induce foci efficiently in fibroblast cultures.
Autor:
R H, Bassin, L E, Benade
Publikováno v:
Immunology series. 51
Publikováno v:
Experimental Biology and Medicine. 125:1242-1246
SummaryPreliminary studies on the transformation of hamster embryo cells by a murine sarcoma virus are reported. Although hamster embryo cells are readily transformed by high concentrations of this virus, they are much less sensitive than are mouse e
Publikováno v:
Cancer research. 47(16)
Two events which commonly occur during transformation of murine and avian fibroblasts by retroviral oncogenes are production of transforming growth factor alpha (TGF-alpha) and suppression of tropomyosin synthesis. TGF has been proposed as a mediator
Autor:
A Rein, R H Bassin
Publikováno v:
Journal of virology. 28(2)
Clones 8A and NP-N, which appear to be infected with replication-defective variants of murine leukemia virus, produce particles which do not form plques in the XC test. These particles formed XC plaques when amphotropic murine leukemia virus, which i