El receptor 2 de VEGF (VEGFR2) y el receptor 1 de la PTH (PTH1R) actúan como mediadores de la respuesta anti-apoptótica al estímulo mecánico en las células osteocíticas MLO-Y4

Autor: Maycas M, Fernández de Castro L, Bravo B, García de Durango C, Forriol F, R. Gortázar A, Esbrit P

Publikováno v: Revista de Osteoporosis y Metabolismo Mineral, Vol 7, Iss 4, Pp 91-97 (2015)

La estimulación mecánica juega un papel fundamental en el mantenimiento de la masa ósea. Dicha estimulación previene la apoptosis de los osteocitos por un mecanismo que implica la acumulación de β-catenina y la translocación nuclear de quinasa

Externí odkaz: https://doaj.org/article/aa8b73ba3fd14058b06786e0691803eb

Optimization and validation of a chiral CE-LIF method for quantitation of aspartate, glutamate and serine in murine osteocytic and osteoblastic cells

Autor: Lorenzo, Maria Paz, Valiente, Luis, Buendia, Irene, R. Gortázar, Arancha, Garcia, Antonia

Publikováno v: In Journal of Chromatography B 1 September 2020 1152

Contributors

Autor: Giulia Abate, Maryam Abshirini, Verónica Alonso, Luis Álvarez-Carrión, Fawaz Alzaid, Sergio Ammendola, Shailendra Anoopkumar-Dukie, Juan A. Ardura, Sylvette Ayala-Peña, Bin Bao, Jyoti Batra, Maurizio Battino, Francielle Garghetti Battiston, Francesco Bellanti, Iris F.F. Benzie, Brunna Cristina Bremer Boaventura, Aurelio Lo Buglio, Andrew C. Bulmer, Antonio Camargo, Francieli Cembranel, Vanessa Corralo, Marco D’Agostino, Javier Delgado-Lista, Patricia Faria Di Pietro, Mathias Abiodun Emokpae, Susana Esteban, Tahereh Farkhondeh, Maria Cristina Florio, Antonio Garcia-Rios, Emiliana Giacomello, Maria Isabel Gonçalves da Silva, Arancha R. Gortázar, Francisco M. Gutierrez-Mariscal, Waseem Hassan, Mina Hemmati, Osaretin Godwin Igharo, Beata Jasiewicz, Manuel Jimenez-García, Jean Paul Kamdem, Mayuree Kanlayavattanakul, Yumi Kitahiro, Miyuki Kobara, Masaaki Kurasaki, Teresa Lino-Neto, Xiaoyan Liu, Guillermo López-Lluch, Jose Lopez-Miranda, Nattaya Lourith, Janice G. Lozada-Delgado, E.S. Mackinnon, Alessandra Magenta, Guilhermina Marques, Maryam Moossavi, David Moranta, Tetsuo Nakata, María D. Navarro-Hortal, Plácido Navas, Lucie Orliaguet, Vinood B. Patel, Francisco Perez-Jimenez, Pablo Pérez-Martinez, Ananda S. Prasad, Victor R. Preedy, Mina Yamazaki Price, José L. Quiles, Gladys Rai, Rajkumar Rajendram, A.V. Rao, L.G. Rao, Russel J. Reiter, José M. Romero-Márquez, Sergio A. Rosales-Corral, Wiramon Rungratanawanich, Clodoaldo Antônio De Sá, Takeshi Saito, Saeed Samarghandian, Eunice Santos, Fiorella Sarubbo, Rahul Saxena, Anna Scotto d’Abusco, Mahendran Sekar, Makio Shibano, Arleta Sierakowska, Sara Sileno, Gity Sotoudeh, Mariana Séfora Bezerra Sousa, Diego de Souza Buarque, Silvia Tejada, Rolf Teschke, Hiroe Toba, Luana Toniolo, Carlos A. Torres-Ramos, Daniela Uberti, Alfonso Varela-López, Gianluigi Vendemiale, Tran Dang Xuan, Elena M. Yubero-Serrano, Mehreen Zafar, Tayebeh Zeinali

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a121cd4cff35dc274df3a676ae8ee727
https://doi.org/10.1016/b978-0-12-818698-5.09991-0

Opposite Effects of Mechanical Action of Fluid Flow on Proangiogenic Factor Secretion From Human Adipose-Derived Stem Cells With and Without Oxidative Stress

Autor: Beatriz, Bravo, Cira, García de Durango, Álvaro, González, Arancha R, Gortázar, Xavier, Santos, Jerónimo, Forteza-Vila, Fernando, Vidal-Vanaclocha

Publikováno v: Journal of cellular physiology. 232(8)

Mechanical forces, hypoxia, and oxidative stress contribute to skin renewal, perfusion, and wound healing, but how are they regulating subcutaneous adipose-derived stem cells (ASCs) in the inflammatory microenvironment associated to skin repair and d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5e38d75bafa8088815db8618c22bf5ef
https://pubmed.ncbi.nlm.nih.gov/27925206

Role of the Parathyroid Hormone Type 1 Receptor (PTH1R) as a Mechanosensor in Osteocyte Survival

Autor: Marta, Maycas, Juan A, Ardura, Luis F, de Castro, Beatriz, Bravo, Arancha R, Gortázar, Pedro, Esbrit

Publikováno v: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30(7)

Osteocytes have a major role in the control of bone remodeling. Mechanical stimulation decreases osteocyte apoptosis and promotes bone accrual, whereas skeletal unloading is deleterious in both respects. PTH1R ablation or overexpression in osteocytes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6174f44b30f8283cdef0044d95932dd7
https://pubmed.ncbi.nlm.nih.gov/25529820