Zobrazeno 1 - 10
of 46
pro vyhledávání: '"R G. Vickery"'
Autor:
Mike Ero, Kathryn Kersey, J A M Smith, R G Vickery, S.M. Amagasu, A. Hopkins, D.L. Higgins, D.T. Beattie
Publikováno v:
Vascular Pharmacology. 58:150-156
The 5-HT(4) receptor agonists, and gastrointestinal (GI) prokinetic agents, cisapride and tegaserod, lack selectivity for the 5-HT(4) receptor. Cisapride is a potent human ether-à-go-go-related gene (hERG) potassium channel inhibitor while cisapride
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47d9050acab9ec6890eb46024b90c3d8
https://doi.org/10.1016/j.vph.2012.11.002
https://doi.org/10.1016/j.vph.2012.11.002
Autor:
J A M Smith, Patrick P.A. Humphrey, D T Beattie, N Mai, M D O'Keefe, R G Vickery, M. Teresa Pulido-Rios, E Kaufman
Publikováno v:
British Journal of Pharmacology. 150:782-791
Background and purpose: 5-HT4 receptor agonists are used therapeutically to treat disorders of reduced gastrointestinal motility. Since such compounds are evaluated in guinea-pigs, we cloned, expressed and pharmacologically characterized the guinea-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f9af4043e1d1937e51133ed44edba21
https://doi.org/10.1038/sj.bjp.0707154
https://doi.org/10.1038/sj.bjp.0707154
Autor:
R G Vickery, J A M Smith, M. Teresa Pulido-Rios, S.R. Armstrong, N Mai, Patrick P.A. Humphrey, C. Sandlund, D T Beattie, J.L. McCullough, C Richardson, D. Marquess
Publikováno v:
British Journal of Pharmacology. 143:549-560
Tegaserod (Zelnorm®) is a potent 5-hydroxytryptamine4 (5-HT4) receptor agonist with clinical efficacy in disorders associated with reduced gastrointestinal motility and transit. The present study investigated the interaction of tegaserod with 5-HT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e64e3cfda36b8bb56bf1302f77a5c79
https://doi.org/10.1038/sj.bjp.0705929
https://doi.org/10.1038/sj.bjp.0705929
Autor:
N Mai, J A M Smith, R G Vickery, R Chang, J Martin, E Kaufman, D. Marquess, Jeremy Hembrador, S.M. Amagasu, M D O'Keefe, C Gee
Publikováno v:
Receptors and Channels. 10:11-23
A novel, membrane potential sensitive dye and a fluorescence imaging plate reader (FLIPR) have been used to characterize the pharmacological properties of rat Na(v)1.8 voltage-gated sodium channels (VGSC) in parallel with rat Na(v)1.2a and human Na(v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f93f84d9579162e5b274ed7991aed6f
https://doi.org/10.3109/10606820490270410
https://doi.org/10.3109/10606820490270410
Autor:
Dunker C; European Institute for Molecular Imaging (EIMI), University of Muenster, Muenster, Germany.; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, Tübingen, Germany., Schlegel K; European Institute for Molecular Imaging (EIMI), University of Muenster, Muenster, Germany., Junker A; European Institute for Molecular Imaging (EIMI), University of Muenster, Muenster, Germany.; Werner Siemens Imaging Center, Department of Preclinical Imaging and Radiopharmacy, University of Tübingen, Tübingen, Germany.
Publikováno v:
Archiv der Pharmazie [Arch Pharm (Weinheim)] 2024 Nov 24, pp. e2400700. Date of Electronic Publication: 2024 Nov 24.
Autor:
R G, Vickery, N, Mai, E, Kaufman, D T, Beattie, T, Pulido-Rios, M, O'Keefe, P P A, Humphrey, J A M, Smith
Publikováno v:
British journal of pharmacology. 150(6)
5-HT(4) receptor agonists are used therapeutically to treat disorders of reduced gastrointestinal motility. Since such compounds are evaluated in guinea-pigs, we cloned, expressed and pharmacologically characterized the guinea-pig 5-HT(4) and human 5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6905f9b85ea7c76d4add482f3531b057
https://pubmed.ncbi.nlm.nih.gov/17293885
https://pubmed.ncbi.nlm.nih.gov/17293885
Autor:
D T, Beattie, J A M, Smith, D, Marquess, R G, Vickery, S R, Armstrong, T, Pulido-Rios, J L, McCullough, C, Sandlund, C, Richardson, N, Mai, P P A, Humphrey
Publikováno v:
British journal of pharmacology. 143(5)
1 Tegaserod (Zelnorm) is a potent 5-hydroxytryptamine4 (5-HT4) receptor agonist with clinical efficacy in disorders associated with reduced gastrointestinal motility and transit. The present study investigated the interaction of tegaserod with 5-HT2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7ce098e6e9ce764d80ec0fd8b7360426
https://pubmed.ncbi.nlm.nih.gov/15466450
https://pubmed.ncbi.nlm.nih.gov/15466450
Autor:
R G, Vickery, S M, Amagasu, R, Chang, N, Mai, E, Kaufman, J, Martin, J, Hembrador, M D, O'Keefe, C, Gee, D, Marquess, J A M, Smith
Publikováno v:
Receptorschannels. 10(1)
A novel, membrane potential sensitive dye and a fluorescence imaging plate reader (FLIPR) have been used to characterize the pharmacological properties of rat Na(v)1.8 voltage-gated sodium channels (VGSC) in parallel with rat Na(v)1.2a and human Na(v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac203cbdac7ec9a3875b8b5807175db0
https://pubmed.ncbi.nlm.nih.gov/14769548
https://pubmed.ncbi.nlm.nih.gov/14769548
Publikováno v:
The Journal of General Physiology
We have cloned the cDNA for a squid Kvl potassium channel (SqKv1A). SqKv1A mRNA is selectively expressed in giant fiber lobe (GFL) neurons, the somata of the giant axons. Western blots detect two forms of SqKv1A in both GFL neuron and giant axon samp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::93b1810d7c09ed9e97f78b2926cbe98f
https://pubmed.ncbi.nlm.nih.gov/8882864
https://pubmed.ncbi.nlm.nih.gov/8882864
Autor:
Choi, Sunho1,2 (AUTHOR) orsunho@gmail.com, Lee, Min Jung2 (AUTHOR), Ahn, Kwang‐Hyun1 (AUTHOR)
Publikováno v:
Bulletin of the Korean Chemical Society. Apr2023, Vol. 44 Issue 4, p370-379. 10p.