Zobrazeno 1 - 10
of 81
pro vyhledávání: '"R G Roeder"'
Autor:
Xiao-Feng Qin, Ziva Misulovin, Yan Luo, Heikyung Suh, Jay Wayne, Michel C. Nussenzweig, R. G. Roeder
Publikováno v:
The EMBO Journal. 13:5967-5976
Altered transcription is a recurrent theme in the field of cancer biology. But despite the central role of transcription in transformation, little is known about the mechanism by which dominant nuclear oncogenes induce malignancies. Homeobox family p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79b7f03cadf56db3d2a74733fb13e957
https://doi.org/10.1002/j.1460-2075.1994.tb06942.x
https://doi.org/10.1002/j.1460-2075.1994.tb06942.x
Autor:
Westley H. Reeves, H. G. Stunnenberg, Chih-Hao Chou, Jingsong Wang, R. G. Roeder, J. Schmitt, Minoru Satoh, Alessandra Pierani
Publikováno v:
Journal of Cell Science. 107:3223-3233
The Ku autoantigen is a heterodimer of 70 kDa (p70) and -80 kDa (p80) subunits that is the DNA-binding component of a DNA-dependent protein kinase (DNA-PK). The 350 kDa (p350) catalytic subunit of DNA-PK phosphorylates Sp-1, Oct-1, p53 and RNA polyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc8317fd2815ee3d67a111ee709bb911
https://doi.org/10.1242/jcs.107.11.3223
https://doi.org/10.1242/jcs.107.11.3223
Publikováno v:
Molecular and Cellular Biology. 14:3927-3937
We have isolated from a crude Hela cell cofactor fraction (USA) a novel positive cofactor that cooperates with the general transcription machinery to effect efficient stimulation of transcription by GAL4-AH, a derivative of the Saccharomyces cerevisi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fc21116bf72fe8f02f69d75253097dc
https://doi.org/10.1128/mcb.14.6.3927
https://doi.org/10.1128/mcb.14.6.3927
Autor:
Shinya Yamashita, Tetsuro Kokubo, R. Takada, R. G. Roeder, Da-Wei Gong, Yoshihiro Nakatani, Masami Horikoshi
Publikováno v:
Molecular and Cellular Biology. 13:7859-7863
Transcription initiation factor TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. To further understand the role of the 85-kDa TFIID subunit (p85), we have cloned the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bea5a7c99933c1e7efaf27ce52d988d
https://doi.org/10.1128/mcb.13.12.7859-7863.1993
https://doi.org/10.1128/mcb.13.12.7859-7863.1993
Autor:
Yoshihiro Nakatani, R. Takada, Masami Horikoshi, Tetsuro Kokubo, Shinya Yamashita, R. G. Roeder, Da-Wei Gong
Publikováno v:
Scopus-Elsevier
A TATA box-binding initiation factor, TFIID, plays a central role in the transcriptional regulation by activators. Using anti-TFIID tau (a TATA box-binding component of native TFIID) immunoaffinity chromatography, nine polypeptides (230, 110, 85, 62,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31720d3e07f69f153a694f17768e01dd
https://doi.org/10.1016/s0021-9258(19)85368-1
https://doi.org/10.1016/s0021-9258(19)85368-1
Autor:
Koji Hisatake, R. G. Roeder, Yoshihiro Nakatani, Shinya Yamashita, Katsumi Doi, Masami Horikoshi, Tetsuro Kokubo
Publikováno v:
Science. 261:463-466
Transcription initiation factor TFIIB recruits RNA polymerase II to the promoter subsequent to interaction with a preformed TFIID-promoter complex. The domains of TFIIB required for binding to the TFIID-promoter complex and for transcription initiati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c2ed039320d4cff431caf01422ed958
https://doi.org/10.1126/science.8332911
https://doi.org/10.1126/science.8332911
Publikováno v:
Nature. 363:744-747
The protein TFIIB is a general transcription initiation factor that interacts with a promoter complex (D.DNA) containing the TATA-binding subunit (TFIID tau, or TBP) of TFIID to facilitate subsequent interaction with RNA polymerase II (ref. 2) throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce4362a5b2197eced3f301452fca69f6
https://doi.org/10.1038/363744a0
https://doi.org/10.1038/363744a0
Autor:
Da-Wei Gong, Masami Horikoshi, Yoshihiro Nakatani, R. G. Roeder, Tetsuro Kokubo, S. Yamashita
Publikováno v:
Genes & Development. 7:1033-1046
A Drosophila cDNA encoding the largest TFIID subunit (p230) was isolated using a degenerate oligodeoxynucleotide probe based on an amino acid sequence of the purified protein. The entire cDNA sequence contains an open reading frame encoding a polypep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a320e19889a98a89a4c99a9c0d0f958
https://doi.org/10.1101/gad.7.6.1033
https://doi.org/10.1101/gad.7.6.1033
Publikováno v:
Scopus-Elsevier
ResearcherID
ResearcherID
We have taken a combined genetic and biochemical approach to study TATA-binding protein (TBP) structure-function relationships. Using site-directed mutagenesis coupled with a screen for conditional lethal growth, we have isolated a number of temperat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8038447578d1c41744c028040cd9079
https://doi.org/10.1016/s0021-9258(18)53495-5
https://doi.org/10.1016/s0021-9258(18)53495-5
Publikováno v:
The Journal of Immunology. 146:2678-2686
High titer autoantibodies to the Ku Ag, a DNA-protein complex containing 70- and approximately 80-kDa protein subunits (p70 and p80, respectively), are found in sera of certain patients with systemic lupus erythematosus and related disorders. Autoepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9709bdcb729b3fba981bda124d21097
https://doi.org/10.4049/jimmunol.146.8.2678
https://doi.org/10.4049/jimmunol.146.8.2678