Zobrazeno 1 - 10
of 41
pro vyhledávání: '"R G Mehta"'
Publikováno v:
Pure and Applied Chemistry. 70:373-376
Structural modifications of the side-chain of vitamin D lead potentially to analogs in which a separation is effected between calcemic activity and cellular differentiation. Vitamin D analogs are used clinically for diseases involving cell proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09023b76f41fd9bcd03bc8d8ab29832a
https://doi.org/10.1351/pac199870020373
https://doi.org/10.1351/pac199870020373
Publikováno v:
ChemInform. 29
Structural modifications of the side-chain of vitamin D lead potentially to analogs in which a separation is effected between calcemic activity and cellular differentiation. Vitamin D analogs are used clinically for diseases involving cell proliferat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::350af7402680b303d43ae9e2cd3e9fbd
https://doi.org/10.1002/chin.199844335
https://doi.org/10.1002/chin.199844335
Publikováno v:
Ciba Foundation Symposium 113-Retinoids, Differentiation and Disease
Certain retinoids serve as effective chemopreventive agents against breast cancer. The effective retinoids are also antiproliferative agents for the mammary gland both in vivo and in vitro. N-(4-hydroxyphenyl)retinamide (HPR) can inhibit the occurren
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b619dfe26f30cd5e0b14649f9f5ac4d0
https://doi.org/10.1002/9780470720943.ch10
https://doi.org/10.1002/9780470720943.ch10
Publikováno v:
Cancer research. 61(20)
Trans-3,4',5-trihydroxystilbene (resveratrol), a phytoalexin present in grapes and grape products such as wine, has been identified as a chemopreventive agent. Recent studies performed with MCF-7 human breast cancer cells have demonstrated superestro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::dfaca700158c02e156570d5b052e7fc5
https://pubmed.ncbi.nlm.nih.gov/11606380
https://pubmed.ncbi.nlm.nih.gov/11606380
Publikováno v:
Anticancer research. 21(3B)
Non-physiological inducers of terminal differentiation have been used as novel therapies for the prevention and therapy of cancer. We have used cultured HL-60 promyelocytic cells to monitor differentiation, proliferation and cell death events as indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1431c4664d363fd294ea0e631783f5bc
https://pubmed.ncbi.nlm.nih.gov/11497257
https://pubmed.ncbi.nlm.nih.gov/11497257
Autor:
S K, Lee, Z H, Mbwambo, H, Chung, L, Luyengi, E J, Gamez, R G, Mehta, A D, Kinghorn, J M, Pezzuto
Publikováno v:
Combinatorial chemistryhigh throughput screening. 1(1)
Since reactive oxygen radicals play an important role in carcinogenesis and other human disease states, antioxidants present in consumable fruits, vegetables, and beverages have received considerable attention as cancer chemopreventive agents. Thus,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8729c385b2eface7ed1331c91532d5b
https://pubmed.ncbi.nlm.nih.gov/10499128
https://pubmed.ncbi.nlm.nih.gov/10499128
Autor:
C, Gerhauser, S K, Lee, J W, Kosmeder, R M, Moriarty, E, Hamel, R G, Mehta, R C, Moon, J M, Pezzuto
Publikováno v:
Cancer research. 57(16)
Deguelin, a plant-derived rotenoid, mediates potent chemopreventive responses through transcriptional regulation of phorbol ester-induced ornithine decarboxylase (ODC) activity. To explore the mechanism of this effect, the activity of this compound w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b8a7b1ca98f506c94daa1a9399213d4
https://pubmed.ncbi.nlm.nih.gov/9270009
https://pubmed.ncbi.nlm.nih.gov/9270009
Autor:
C, Gerhäuser, M, You, J, Liu, R M, Moriarty, M, Hawthorne, R G, Mehta, R C, Moon, J M, Pezzuto
Publikováno v:
Cancer research. 57(2)
Chemoprevention involves the use of natural or synthetic substances to reduce the risk of developing cancer. Two dietary components capable of mediating chemopreventive activity in animal models by modulation of drug-metabolizing enzymes are sulforap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9390445be54c873d91b691e5e76a1884
https://pubmed.ncbi.nlm.nih.gov/9000567
https://pubmed.ncbi.nlm.nih.gov/9000567
Publikováno v:
Anticancer research. 16(6A)
Soy-based diets, rich in the isoflavones genistein and daidzein, are thought to protect against breast and prostate cancer. We used the N-methyl-N-nitrosourea (MNU)-induced mammary carcinogenesis animal model to test the effectiveness of these two is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a77f8535276e1e4412b760ecead402f4
https://pubmed.ncbi.nlm.nih.gov/9042303
https://pubmed.ncbi.nlm.nih.gov/9042303
Publikováno v:
Anticancer research. 14(5A)
Seventy natural and synthetic compounds were tested for potential to inhibit mutation induced by 7,12-dimethylbenz(a)anthracene (DMBA) in Salmonella typhimurium strain TM677. Results were compared with their ability to inhibit DMBA-induced preneoplas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6148166cd936c4725534f0793badd8e5
https://pubmed.ncbi.nlm.nih.gov/7847810
https://pubmed.ncbi.nlm.nih.gov/7847810