Zobrazeno 1 - 6 of 6 pro vyhledávání: '"R G Almquist"'
1
Stabilized Analogs of Thymopentin. 2. 1,2- and 3,4-Ketomethylene Pseudopeptides
Autor: I Uchida, Smith Rl, A K Judd, C K Hiebert, R G Almquist, Waud Wr, Dousman L, Joseph I. DeGraw
Publikováno v: Journal of Medicinal Chemistry. 40:2398-2406
In this second paper in a series of three studies of stable analogs of thymopentin (Arg1-Lys2-Asp3-Val4-Tyr5), the synthesis of analogs stabilized at peptide bonds 1,2 and 3,4 via insertion of ketomethylene units is described. A tris(carbobenzyloxy)a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f90188d4bac5df077db3b1094584a911
https://doi.org/10.1021/jm9508043
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2
Stabilized analogs of thymopentin. 1. 4,5-Ketomethylene pseudopeptides
Autor: Dousman L, I Uchida, A K Judd, J Crase, C K Hiebert, R G Almquist, W. T. Colwell, Waud Wr, T. Hayano, Smith Rl, Joseph I. DeGraw
Publikováno v: Journal of medicinal chemistry. 40(15)
The pentapeptide, thymopentin (Arg1-Lys2-Asp3-Val4-Tyr5) is known for its activity as an immunomodulating drug, but with limited half-life in plasma. In this first paper of a series of three studies, the synthesis of analogs stabilized at the peptide
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f27e7129bebbb799087e79b755c8795f
https://pubmed.ncbi.nlm.nih.gov/9240353
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