Zobrazeno 1 - 10
of 28
pro vyhledávání: '"R G, Vile"'
Autor:
Paul Harris, C L White, Mohan Hingorani, R. Seth, Christopher M. Nutting, V K Agrawal, R G Vile, M Kelly, Kevin J. Harrington, Hardev Pandha, Ahad A. Rahim, Alan Melcher, K M Copeland, Yolanda Barbachano, Colin D. Porter
Publikováno v:
Gene Therapy. 16:78-92
Transfer of healthy autologous tissue as a microvascular free flap facilitates reconstruction during ablative cancer surgery. In addition to filling surgical defects, free flaps might concentrate viral vectors at the tumour bed and mediate local ther
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07778c25487d5c4212f2c669824f2027
https://doi.org/10.1038/gt.2008.140
https://doi.org/10.1038/gt.2008.140
Autor:
D C, Mansfield, J N, Kyula, N, Rosenfelder, J, Chao-Chu, G, Kramer-Marek, A A, Khan, V, Roulstone, M, McLaughlin, A A, Melcher, R G, Vile, H S, Pandha, V, Khoo, K J, Harrington
Publikováno v:
Gene Therapy
Oncolytic strains of vaccinia virus are currently in clinical development with clear evidence of safety and promising signs of efficacy. Addition of therapeutic genes to the viral genome may increase the therapeutic efficacy of vaccinia. We evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5242a1036583ec94b2c634243d4b39be
https://pubmed.ncbi.nlm.nih.gov/26814609
https://pubmed.ncbi.nlm.nih.gov/26814609
Publikováno v:
The Journal of Urology. :1220-1233
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac865133657da71949abef89fa589597
https://doi.org/10.1097/00005392-200110000-00003
https://doi.org/10.1097/00005392-200110000-00003
Publikováno v:
Gene Therapy. 6:1552-1557
We recently showed that retroviral vectors can be targeted through protease substrate interactions. Infectivity is blocked by a polypeptide fused to the viral envelope glycoprotein (SU) and is restored when a protease cleaves the connecting linker, r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8bcf1845ea6935d14dde4bee014e53e
https://doi.org/10.1038/sj.gt.3300982
https://doi.org/10.1038/sj.gt.3300982
Publikováno v:
ResearcherID
British Journal of Cancer
British Journal of Cancer
The Second Meeting of the British Society for Immunology Tumour Immunology Affinity Group (TIAG) took place at King's College (London, UK) on 17-18 June 1997 and brought together over 100 tumour immunologists from the UK and abroad. In contrast to pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b7c18601e09cf2ee1010c6723b567ec
https://doi.org/10.1038/bjc.1998.300
https://doi.org/10.1038/bjc.1998.300
Publikováno v:
Biochemical Society Transactions. 25:717-722
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7df7f82d27109ce397619574c177636
https://doi.org/10.1042/bst0250717
https://doi.org/10.1042/bst0250717
Publikováno v:
British Medical Bulletin. 51:647-655
Melanin biosynthesis is limited to melanocytes partly as a consequence of transcriptional regulation of the enzymes involved in this pathway. Promoter sequences of these enzyme genes may be utilised to drive expression of complementary DNA coding for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c85e25a7b61db397b1e1181ad3cb89ea
https://doi.org/10.1093/oxfordjournals.bmb.a072984
https://doi.org/10.1093/oxfordjournals.bmb.a072984
Publikováno v:
British Journal of Surgery. 80:566-572
Gene transfer techniques have now achieved clinical realization in the wake of recent advances in recombinant DNA technology, together with increased understanding of the molecular biology and immunology of cancer. These novel treatments, and their a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62ba2f09de52b3eebeb7758d12b78850
https://doi.org/10.1002/bjs.1800800507
https://doi.org/10.1002/bjs.1800800507
Autor:
S N, Markovic, L A, Erickson, T J, Flotte, L A, Kottschade, R R, McWilliams, J W, Jakub, D R, Farley, N V, Tran, S E, Schild, K R, Olivier, S, Vuk-Pavlovic, A, Sekulic, R H, Weenig, J S, Pulido, J F, Quevedo, R G, Vile, G A, Wiseman, I, Stoian, M R, Pittelkow
Publikováno v:
Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia. 144(1)
Metastatic malignant melanoma is an incurable malignancy with extremely poor prognosis. Patients bearing this diagnosis face a median survival time of approximately 9 months with a probability of surviving 5 years after initial presentation at less t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::10305344210fbf2ab43412f6de2f293e
https://pubmed.ncbi.nlm.nih.gov/19218908
https://pubmed.ncbi.nlm.nih.gov/19218908
Publikováno v:
The Journal of clinical endocrinology and metabolism. 86(7)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::95aeaeff251a0d4617c4b54331e0490d
https://pubmed.ncbi.nlm.nih.gov/11443208
https://pubmed.ncbi.nlm.nih.gov/11443208