Výsledky vyhledávání - "R G, Pergolizzi"

Gene-enhanced tissue engineering: applications for wound healing using cultured dermal fibroblasts transduced retrovirally with the PDGF-B gene

Autor: A S, Breitbart, J M, Mason, C, Urmacher, M, Barcia, R T, Grant, R G, Pergolizzi, D A, Grande

Publikováno v: Annals of plastic surgery. 43(6)

The treatment of difficult wounds remains a considerable clinical challenge. The goal of this study was to determine whether genetic augmentation of dermal cells on resorbable matrices can stimulate the healing process, leading to increased tissue re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fff86cf0a1b026e2206ae482dda22950
https://pubmed.ncbi.nlm.nih.gov/10597824

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Human serum-resistant retroviral vector particles from galactosyl (alpha1-3) galactosyl containing nonprimate cell lines

Autor: R G Pergolizzi, S Teichberg, Leslie O. Goodwin, K C Cronin, James M. Mason, D E Guzowski, D Porti

Publikováno v: Gene therapy. 6(8)

Retroviral vector particles (RVP) which are resistant to inactivation by human serum will be needed for many in vivo gene therapy applications. Murine-based producer cell lines generate RVP which are inactivated by human serum, reportedly due to the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cdef9acda00043def9612e93881450
https://pubmed.ncbi.nlm.nih.gov/10467364

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Expression of human bone morphogenic protein 7 in primary rabbit periosteal cells: potential utility in gene therapy for osteochondral repair

Autor: Arnold S. Breitbart, James M. Mason, Michele Barcia, DA Grande, R G Pergolizzi, R Grant

Publikováno v: Gene therapy. 5(8)

A commonly encountered problem in orthopedics is bone and cartilage tissue injury which heals incompletely or without full structural integrity. This necessitates development of improved methods for treatment of injuries which are not amenable to tre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e2e36607d6700d600d997ade96e900e
https://pubmed.ncbi.nlm.nih.gov/10326033

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Molecular characterization of a variant Ph1 translocation t(9;22;11) (q34;q11;q13) in chronic myelogenous leukemia (CML) reveals the translocation of the 3'-part of BCR gene to the chromosome band 11q13

Autor: P R, Koduru, J C, Goh, R G, Pergolizzi, S M, Lichtman, J D, Broome

Publikováno v: Oncogene. 8(12)

We performed cloning and sequence analysis of translocation junctions at 11q- and 22q- (Ph1) chromosomes and the corresponding germline DNAs of a variant Ph1-positive CML with t(9;22;11)(q34;q11;q13). Southern blot analysis using probes for different

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::88b9e6541cc2f421ed428f3b138c0df9
https://pubmed.ncbi.nlm.nih.gov/8247527

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Analysis of a CGG sequence at the FMR-1 locus in fragile X families and in the general population

Autor: K, Snow, L K, Doud, R, Hagerman, R G, Pergolizzi, S H, Erster, S N, Thibodeau

Publikováno v: American journal of human genetics. 53(6)

In this study, we have characterized a CGG repeat at the FMR-1 locus in more than 100 families (more than 500 individuals) presenting for fragile X testing and in 247 individuals from the general population. Both Southern blot and PCR-based assays we

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cd1b68c6d066291e2948c07e8158efa0
https://pubmed.ncbi.nlm.nih.gov/7902673

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Translation of globin messenger RNA modified by benzo[a]pyrene 7,8-dihydrodiol 9,10-oxide in a wheat germ cell-free system

Autor: R E Jones, D Grunberger, R G Pergolizzi

Publikováno v: Journal of Biological Chemistry. 255:390-394

Poly(U/sub 3/G) and rabbit globin mRNA were modified with the active carcinogenic metabolite of benzo(a)pyrene, (+-)-7..beta..,8..cap alpha..-dihydroxy-9..cap alpha..,10..cap alpha..-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene, and the effects of modific

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b7395d6e2ee143756c63b988282f280a
https://doi.org/10.1016/s0021-9258(19)86185-9

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Formation of phenylalanine transfer RNA lacking the wye base in Vero cells during methionine starvation

Autor: D L Engelhardt, R G Pergolizzi, D Grunberger

Publikováno v: Journal of Biological Chemistry. 253:6341-6343

Vero, a cell line derived from African green monkey kidney, normally contains a single species of tRNAPhe (tRNA2Phe), containing a hypermodified base, wye (originally called Y), next to the 3' end of the anticodon. When methionine is removed from the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4735337f262969c6b78ef65ce9db41ec
https://doi.org/10.1016/s0021-9258(19)46937-8

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Alterations in post-transcriptional modification of the Y base in phenylalanine tRNA from tumor cells

Autor: D, Grunberger, R G, Pergolizzi, Y, Kuchino, J F, Mushinski, S, Nishimura

Publikováno v: Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer. 84

Various tumor cells contain chromatographically distinct isoacceptor tRNA species. To decide whether the tumor-specific species represent an expression of a separate tRNA gene or only an undermodified form of normal tRNAPhe, nucleotide sequences of t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2e9bcb9653b1f0a7edb423709c8cc6b7
https://pubmed.ncbi.nlm.nih.gov/6405457

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