Zobrazeno 1 - 10
of 737
pro vyhledávání: '"R G, Knowles"'
Autor:
Hu, Hong1 (AUTHOR), He, Wenhui1 (AUTHOR), Qu, Zhiguang1 (AUTHOR), Dong, Xiang1 (AUTHOR), Ren, Zhiyong1 (AUTHOR), Qin, Mengyuan1 (AUTHOR), Liu, Hao1 (AUTHOR), Zheng, Lu1 (AUTHOR), Huang, Junbin1 (AUTHOR), Chen, Xiao‐Lin1 (AUTHOR) chenxiaolin@mail.hzau.edu.cn
Publikováno v:
Advanced Science. 7/10/2024, Vol. 11 Issue 26, p1-16. 16p.
Publikováno v:
Amino Acids. 31:101-109
This study has characterised the transport mechanism(s) for the novel and selective inhibitor of inducible nitric oxide synthase (iNOS), GW274150, in murine macrophage J774 cells. Transport of GW274150 was saturable (K(m) = 0.24 +/- 0.01 mM and V(max
Publikováno v:
Endocrinology. 135:2473-2478
The mechanism for myometrial quiescence during pregnancy is unknown. cGMP plays an integral role in the relaxation of smooth muscle, and nitric oxide (NO) is the most important endogenous activator of soluble guanylate cyclase. The purpose of this st
Publikováno v:
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). 65(1)
SummaryAcute rheumatic-like heart lesions have been produced in mice by parenteral injection of egg white on repeated occasions. Minimal lesions may also occur in untreated mice, possibly as a result of spontaneous sensitization and shocking by natur
Autor:
S. Moncada, E. A. Higgs, H. F. Hodson, R. G. Knowles, P. Lopez-Jaramillo, T. McCall, R. M. J. Palmer, M. W. Radomski, D. D. Rees, R. Schulz
Publikováno v:
Journal of Cardiovascular Pharmacology. 17:S1-S9
Publikováno v:
Clinical and experimental rheumatology. 26(2)
In osteoarthritis (OA), the balance between catabolic and anabolic mediators and their regulators in cartilage is disturbed. Proinflammatory cytokine interleukin-1 (IL-1) plays a central role in cartilage destruction and nitric oxide (NO) mediates ma
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 298(3)
High concentrations of nitric oxide (NO) produced by the inducible nitric-oxide synthase (iNOS) are associated with ulcerative inflammation and disease activity in colitis. Therefore, inhibition of iNOS serves as a novel experimental approach to trea
Publikováno v:
The Biochemical journal. 357(Pt 3)
This review concentrates on advances in nitric oxide synthase (NOS) structure, function and inhibition made in the last seven years, during which time substantial advances have been made in our understanding of this enzyme family. There is now inform
Autor:
M, Salter, R G, Knowles
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 100
Autor:
R G, Knowles, M, Salter
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 100