Zobrazeno 1 - 7
of 7
pro vyhledávání: '"R G, Kalb"'
Autor:
L. McGurk, J. Mojsilovic-Petrovic, V. M. Van Deerlin, J. Shorter, R. G. Kalb, V. M. Lee, J. Q. Trojanowski, E. B. Lee, N. M. Bonini
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-15 (2018)
Abstract Amyotrophic lateral sclerosis (ALS) is a devastating and fatal motor neuron disease. Diagnosis typically occurs in the fifth decade of life and the disease progresses rapidly leading to death within ~ 2–5 years of symptomatic onset. There
Externí odkaz:
https://doaj.org/article/1ad8af8abf1945e5a8e563fe291f655e
Publikováno v:
Aviation, space, and environmental medicine. 74(6 Pt 1)
Within the mammalian central nervous system (CNS), glutamate receptors play a fundamental role in excitatory neurotransmission and synaptic plasticity. Studies of the neonatal cerebral cortex suggests that rearing environment can influence the dynami
Publikováno v:
Journal of neurochemistry. 76(5)
One approach to studying the functional role of individual NMDA receptor subunits involves the reduction in the abundance of the protein subunit in neurons. We have pursued a strategy to achieve this goal that involves the use of a small guide RNA wh
Publikováno v:
Methods in enzymology. 325
Publikováno v:
Journal of neurobiology. 44(2)
The semaphorin family of proteins constitute one of the major cues for axonal guidance. The prototypic member of this family is Sema3A, previously designated semD/III or collapsin-1. Sema3A acts as a diffusible, repulsive guidance cue in vivo for the
Publikováno v:
Annals of neurology. 46(3)
The selective loss of neurons in Huntington's disease (HD) is caused by the abnormal expansion of the CAG triplet (36 repeats) of the HD gene. Although the molecular events that lead to neuronal death are not clear, it is most likely that mutant HD p
Publikováno v:
The Journal of comparative neurology. 384(2)
Quantitative receptor autoradiography was used to map the distribution in the developing human spinal cord of the three types of ionotropic glutamate receptors. N-methyl-D-Aspartate (NMDA) receptors were labeled with [3H]glutamate, kainic acid (KA) r