Zobrazeno 1 - 10
of 120
pro vyhledávání: '"R Frederick Westbrook"'
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93506 (2014)
BackgroundObesity is associated with excessive consumption of palatable, energy dense foods. The present study used an animal model to examine feeding patterns during exposure to and withdrawal from these foods.MethodsMale Sprague Dawley rats were ex
Externí odkaz:
https://doaj.org/article/78278ea21db04b0ab9c17dad2ba28bf5
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26863 (2011)
How animals make choices in a changing and often uncertain environment is a central theme in the behavioural sciences. There is a substantial literature on how animals make choices in various experimental paradigms but less is known about the way the
Externí odkaz:
https://doaj.org/article/e8399a2dcfec434199a6c86675b97131
Autor:
Kyoko Hasebe, Michael D. Kendig, Nadeem O. Kaakoush, Aynaz Tajaddini, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Animal Microbiome, Vol 4, Iss 1, Pp 1-14 (2022)
Abstract Background Despite well-known effects of diet on gut microbiota diversity, relatively little is known about how maternal diet quality shapes the longitudinal maturation of gut microbiota in offspring. To investigate, we fed female rats stand
Externí odkaz:
https://doaj.org/article/f3af96bb5e364556b133a6770b33fdb6
Autor:
Sarah-Jane Leigh, Nadeem O. Kaakoush, Rosa M. Escorihuela, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Nutrition & Metabolism, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Exercise has been extensively utilised as an effective therapy for overweight- and obesity-associated changes that are linked to health complications. Several preclinical rodent studies have shown that treadmill exercise alongside
Externí odkaz:
https://doaj.org/article/08a887deddc24ec1a4164d48795fe003
Autor:
Jessica Leake, Dana M. Leidl, Belinda P. P. Lay, Justine P. Fam, Madeleine C. Giles, Omar A. Qureshi, R. Frederick Westbrook, Nathan M. Holmes
Activity in the basolateral amygdala complex (BLA) is needed to encode fears acquired through contact with both innate sources of danger (i.e., things that are painful) and learned sources of danger (e.g., being threatened with a gun). However, withi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a497369af8966b5fa9a811bccf988e09
https://doi.org/10.1101/2022.12.05.519226
https://doi.org/10.1101/2022.12.05.519226
It is widely accepted that fear memories are consolidated through protein synthesis-dependent changes in the basolateral amygdala complex (BLA). However, recent studies show that protein synthesis isnotrequired to consolidate the memory of a new dang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a4a181717cb3182027f66606a7ffc87
https://doi.org/10.1101/2022.12.03.518947
https://doi.org/10.1101/2022.12.03.518947
Autor:
Omar A. Qureshi, Jessica Leake, Andrew J. Delaney, Simon Killcross, R. Frederick Westbrook, Nathan M. Holmes
This study examined the effect of danger on consolidation of neutral information in two regions of the rat (male and female) medial temporal lobe: the perirhinal cortex (PRh) and basolateral amygdala complex (BLA). The neutral information was the ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6885e06de7881f2bed2d78324ea16df5
https://doi.org/10.1101/2022.12.02.518124
https://doi.org/10.1101/2022.12.02.518124
Autor:
Michael D. Kendig, Kyoko Hasebe, Aynaz Tajaddini, Nadeem O. Kaakoush, R. Frederick Westbrook, Margaret J. Morris
Publikováno v:
Molecular nutritionfood research.
Maternal obesity increases the risk of health complications in children, highlighting the need for effective interventions. A rat model of maternal obesity to examine whether a diet switch intervention could reverse the adverse effects of an unhealth
Publikováno v:
Journal of Experimental Psychology: Animal Learning and Cognition. 47:91-103
The Hall-Rodriguez (Hall & Rodriguez, 2010) theory predicts that latent inhibition can be facilitated when a target stimulus is preexposed in compound with a second, nontarget stimulus: specifically, latent inhibition will be facilitated when the tar
Publikováno v:
Translational Psychiatry, Vol 10, Iss 1, Pp 1-13 (2020)
Translational Psychiatry
Translational Psychiatry
Diets rich in sugar and saturated fat are associated with cognitive impairments in both humans and rodents with several potential mechanisms proposed. To test the involvement of diet-induced pro-inflammatory signaling, we exposed rats to a high-fat,