Zobrazeno 1 - 10
of 666
pro vyhledávání: '"R Flavell"'
Autor:
Robin Peter, Anil P. Bidkar, Kondapa Naidu Bobba, Luann Zerefa, Chandrashekhar Dasari, Niranjan Meher, Anju Wadhwa, Adam Oskowitz, Bin Liu, Brian W. Miller, Kai Vetter, Robert R. Flavell, Youngho Seo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-13 (2024)
Abstract Radiopharmaceutical therapy using $$\upalpha$$ α -emitting $$^{225}$$ 225 Ac is an emerging treatment for patients with advanced metastatic cancers. Measurement of the spatial dose distribution in organs and tumors is needed to inform treat
Externí odkaz:
https://doaj.org/article/e1d2c9d4e31443c086a6151ba318828e
Autor:
Changhua Mu, Xiaoxi Liu, Andrew Riselli, James Slater, Evelyn Escobar, Duy Dang, Scott Drapeau, Romelyn Delos Santos, Stacy Andosca, Hao Nguyen, Peder E.Z. Larson, Robert Bok, Daniel B. Vigneron, John Kurhanewicz, David M. Wilson, Robert R. Flavell
Publikováno v:
STAR Protocols, Vol 5, Iss 3, Pp 103091- (2024)
Summary: Tumor acidosis is one of the hallmarks indicating the initiation and progression of various cancers. Here, we present a protocol for preparing a hyperpolarized (HP) 13C-bicarbonate tissue pH MRI imaging contrast agent to detect aggressive tu
Externí odkaz:
https://doaj.org/article/26eee672a7554c34a6b37c0d4f69c4ee
Autor:
Alexandre M. Sorlin, Marina López-Álvarez, Jacob Biboy, Joe Gray, Sarah J. Rabbitt, Junaid Ur Rahim, Sang Hee Lee, Kondapa Naidu Bobba, Joseph Blecha, Mathew F.L. Parker, Robert R. Flavell, Joanne Engel, Michael Ohliger, Waldemar Vollmer, David M. Wilson
Publikováno v:
JACS Au, Vol 4, Iss 3, Pp 1039-1047 (2024)
Externí odkaz:
https://doaj.org/article/26fb8a542dcd4adc81aef174d5b3c7bf
Autor:
Jun Li, Tao Huang, Jun Hua, Qiong Wang, Yang Su, Ping Chen, Scott Bidlingmaier, Allan Li, Zhongqiu Xie, Anil P. Bidkar, Sui Shen, Weibin Shi, Youngho Seo, Robert R. Flavell, Daniel Gioeli, Robert Dreicer, Hui Li, Bin Liu, Jiang He
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-13 (2023)
Abstract We recently identified CD46 as a novel prostate cancer cell surface antigen that shows lineage independent expression in both adenocarcinoma and small cell neuroendocrine subtypes of metastatic castration resistant prostate cancer (mCRPC), d
Externí odkaz:
https://doaj.org/article/dda216b0fc2a4b11a9340849cfc3ea50
Autor:
Denis R. Beckford-Vera, Robert R. Flavell, Youngho Seo, Enrique Martinez-Ortiz, Maya Aslam, Cassandra Thanh, Emily Fehrman, Marion Pardons, Shreya Kumar, Amelia N. Deitchman, Vahid Ravanfar, Brailee Schulte, I-Wei Katherine Wu, Tony Pan, Jacqueline D. Reeves, Christopher C. Nixon, Nikita S. Iyer, Leonel Torres, Sadie E. Munter, Tony Hyunh, Christos J. Petropoulos, Rebecca Hoh, Benjamin L. Franc, Lucio Gama, Richard A. Koup, John R. Mascola, Nicolas Chomont, Steven G. Deeks, Henry F. VanBrocklin, Timothy J. Henrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Here, the authors apply positron emission tomography (PET) imaging to visualize HIV tissue-wide burden in infected individuals using a radiolabeled broadly neutralizing antibody, 89Zr-VRC01, and show that PET tracer lymph node uptake positively corre
Externí odkaz:
https://doaj.org/article/42a11e0860df4b12b471a443fa8f7ecb
Autor:
Deep K. Hathi, Wen Li, Youngho Seo, Robert R. Flavell, John Kornak, Benjamin L. Franc, Bonnie N. Joe, Laura J. Esserman, Nola M. Hylton, Ella F. Jones
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Metabolic imaging of the primary breast tumor with 18F-fluorodeoxyglucose ([18F]FDG) PET may assist in predicting treatment response in the neoadjuvant chemotherapy (NAC) setting. Dedicated breast PET (dbPET) is a high-resolution imaging mod
Externí odkaz:
https://doaj.org/article/30e6a4a7f89b4329acae5a910d765f06
Autor:
Courtney Lawhn-Heath, Sue S. Yom, Chienying Liu, Javier E. Villanueva-Meyer, Maya Aslam, Raven Smith, Manpreet Narwal, Roxanna Juarez, Spencer C. Behr, Miguel Hernandez Pampaloni, Jason W. Chan, Christine M. Glastonbury, Thomas A. Hope, Robert R. Flavell
Publikováno v:
EJNMMI Research, Vol 10, Iss 1, Pp 1-10 (2020)
Abstract Background Prostate-specific membrane antigen (PSMA) is expressed in the microvasculature of thyroid cancer. This suggests the potential use of PSMA as a diagnostic agent in patients with aggressive forms of thyroid cancer. The purpose of th
Externí odkaz:
https://doaj.org/article/74f6d538c62e4f3fbf41cdcc2db22e29
68Ga-PSMA-11 PET/MRI: determining ideal acquisition times to reduce noise and increase image quality
Autor:
Vishnu Murthy, Raven L. Smith, Dora H. Tao, Courtney A. Lawhn-Heath, Dave E. Korenchan, Peder E. Z. Larson, Robert R. Flavell, Thomas A. Hope
Publikováno v:
EJNMMI Physics, Vol 7, Iss 1, Pp 1-8 (2020)
Abstract Background In this study, we investigate the impact of increased PET acquisition time per bed position on lesion detectability, standard uptake value, and image noise in 68Ga-PSMA-11 PET/MRI scans. Methods Scans of twenty patients were analy
Externí odkaz:
https://doaj.org/article/013ad5673fed4615a49ec8ff28489e7a
Autor:
Matthew F. L. Parker, Justin M. Luu, Brailee Schulte, Tony L. Huynh, Megan N. Stewart, Renuka Sriram, Michelle A. Yu, Salma Jivan, Peter J. Turnbaugh, Robert R. Flavell, Oren S. Rosenberg, Michael A. Ohliger, David M. Wilson
Publikováno v:
ACS Central Science, Vol 6, Iss 2, Pp 155-165 (2020)
Externí odkaz:
https://doaj.org/article/a434d305c551470082bf3c0807bf3966
Publikováno v:
Pharmaceuticals, Vol 16, Iss 2, p 315 (2023)
Targeted nanotheranostic systems offer significant benefits due to the integration of diagnostic and therapeutic functionality, promoting personalized medicine. In recent years, prostate-specific membrane antigen (PSMA) has emerged as an ideal theran
Externí odkaz:
https://doaj.org/article/0cdb9960c299463c8162ef608b56cbb5