Zobrazeno 1 - 10
of 33
pro vyhledávání: '"R F Graziano"'
Autor:
N A Fanger, D Voigtlaender, C Liu, S Swink, K Wardwell, J Fisher, R F Graziano, L C Pfefferkorn, P M Guyre
Publikováno v:
The Journal of Immunology. 158:3090-3098
The mechanisms responsible for efficient sequestration of Ag by cells of the dendritic cell (DC) lineage remain incompletely characterized. One pathway, internalization of Ag-IgG complexes via CD32 (the type II IgG FcR, Fc gamma RII) enhances Ag pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4fd28e9346b9b2756eb0f525490fcd5
https://doi.org/10.4049/jimmunol.158.7.3090
https://doi.org/10.4049/jimmunol.158.7.3090
Publikováno v:
The Journal of Immunology. 158:872-879
A bispecific fusion protein (H22-EGF) that binds simultaneously to the epidermal growth factor receptor (EGF-R) and to the high affinity receptor for the Fc portion of human IgG, Fc gammaRI (CD64), has been successfully constructed and expressed. For
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468370b88fe66289908ec4f80f6c343f
https://doi.org/10.4049/jimmunol.158.2.872
https://doi.org/10.4049/jimmunol.158.2.872
Autor:
R F Graziano, P R Tempest, P White, T Keler, Y Deo, H Ghebremariam, K Coleman, L C Pfefferkorn, M W Fanger, P M Guyre
Publikováno v:
The Journal of Immunology. 155:4996-5002
The murine mAb 22 (M22) binds to the human high affinity receptor for the Fc portion of IgG (Fc gamma RI). This mAb recognizes an epitope on Fc gamma RI that is distinct from the natural ligand (Fc) binding site, and, therefore, can bind to Fc gamma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3bded9d3abf02a926d02e0e5e4b3f9d
https://doi.org/10.4049/jimmunol.155.10.4996
https://doi.org/10.4049/jimmunol.155.10.4996
Publikováno v:
Methods in molecular medicine. 64
Fc receptors specific for IgG (FcγR) potentiate the immune response by facilitating the interaction between myeloid cells and antibody-coated targets (1-3). Monocyte and neutrophil FcyR engagement can lead to the induction of lytic-type mechanisms a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::04d4c5c39f768f054bec16767bdcc286
https://pubmed.ncbi.nlm.nih.gov/21374276
https://pubmed.ncbi.nlm.nih.gov/21374276
Autor:
R F Graziano, P M Allen
Publikováno v:
The Journal of Immunology. 149:556-561
Using the murine system we have analyzed an immunogenic T cell peptide epitope corresponding to amino acids 96-112 of the simian immunodeficiency virus-negative regulatory protein sequence. This epitope was unusual in that it was strongly immunogenic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3d863a39d010cf710306d020cab10ff
https://doi.org/10.4049/jimmunol.149.2.556
https://doi.org/10.4049/jimmunol.149.2.556
Publikováno v:
The Journal of Immunology. 144:3693-3700
Human alveolar macrophage have three distinct receptors for IgG: FcRI, FcRII, and FcRIII. In order to compare the ability of these receptors to mediate target cell lysis, three different assay systems were examined. First, we studied lysis of chicken
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e79a8de417af2824b1eeab508a555b7
https://doi.org/10.4049/jimmunol.144.10.3693
https://doi.org/10.4049/jimmunol.144.10.3693
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(4)
The FcR for IgA (Fc alpha RI, CD89) is primarily expressed on cytotoxic immune effector cells. By chemically cross-linking F(ab') fragments of the FcR for IgA (Fc alpha RI)-specific mAb (A77) with tumor Ag-specific mAb (anti-HER2/neu and anti-epiderm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::47bc67567ca05609808173b7abbb5d60
https://pubmed.ncbi.nlm.nih.gov/9469424
https://pubmed.ncbi.nlm.nih.gov/9469424
Autor:
T, Valerius, B, Stockmeyer, A B, van Spriel, R F, Graziano, I E, van den Herik-Oudijk, R, Repp, Y M, Deo, J, Lund, J R, Kalden, M, Gramatzki, J G, van de Winkel
Publikováno v:
Blood. 90(11)
Promising results from clinical trials with unconjugated antibodies stimulated renewed interest in immune effector mechanisms of monoclonal antibodies (MoAbs). We investigated the potential of IgA as antibody isotype for cell- or complement-mediated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::720b369f5b8521a8a7692f3993e29236
https://pubmed.ncbi.nlm.nih.gov/9373259
https://pubmed.ncbi.nlm.nih.gov/9373259
Autor:
T, Keler, R F, Graziano, A, Mandal, P K, Wallace, J, Fisher, P M, Guyre, M W, Fanger, Y M, Deo
Publikováno v:
Cancer research. 57(18)
A bispecific antibody, MDX-H210, was developed to target cytotoxic effector cells expressing Fc gamma receptor type I (Fc gammaRI, CD64) to HER2/neu-overexpressing tumor cells. HER2/neu is an appropriate target for immunotherapy due to the high level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fd2456b7bda5458ca4b34c59ea5a049
https://pubmed.ncbi.nlm.nih.gov/9307286
https://pubmed.ncbi.nlm.nih.gov/9307286
Autor:
N A, Fanger, D, Voigtlaender, C, Liu, S, Swink, K, Wardwell, J, Fisher, R F, Graziano, L C, Pfefferkorn, P M, Guyre
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 158(7)
The mechanisms responsible for efficient sequestration of Ag by cells of the dendritic cell (DC) lineage remain incompletely characterized. One pathway, internalization of Ag-IgG complexes via CD32 (the type II IgG FcR, Fc gamma RII) enhances Ag pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::43295a520b552bbf1093fc7289971438
https://pubmed.ncbi.nlm.nih.gov/9120261
https://pubmed.ncbi.nlm.nih.gov/9120261