Zobrazeno 1 - 10
of 37
pro vyhledávání: '"R F, Gagel"'
Autor:
R. F. Gagel
Publikováno v:
Journal of Clinical Endocrinology & Metabolism. 76:809-814
Beyond RET: potential therapeutic approaches for advanced and metastatic medullary thyroid carcinoma
Publikováno v:
Journal of internal medicine. 266(1)
Medullary thyroid carcinoma (MTC) is a rare calcitonin-producing neuroendocrine tumour that originates from the parafollicular C-cells of the thyroid gland. The RET proto-oncogene encodes the RET receptor tyrosine kinase, which has essential roles in
Publikováno v:
Pituitary. 3(4)
This study reports a six year experience with quinagolide (CV205-502) in the treatment of 40 patients with hyperprolactinemia or prolactinoma.Forty patients with hyperprolactinemia were treated with quinagolide (CV 205-502, Norprolac) for 2-72 months
Publikováno v:
Revista medica de Chile. 129(7)
Medullary thyroid carcinoma (MTC) may occur either as a sporadic or familial disease. Multiple endocrine neoplasia (MEN) type 2, inherited as an autosomal dominant disease, is characterized by MTC only (FMTC) or coexistence of MTC with other endocrin
Autor:
H, Lou, R F, Gagel
Publikováno v:
Frontiers of hormone research. 25
Autor:
G J, Cote, J E, Lee, D B, Evans, E, Huang, P N, Schultz, G T, Dang, H, Qiu, S, Shetelbine, R V, Sellin, R F, Gagel
Publikováno v:
Human mutation. 12(3)
Publikováno v:
Cancer research. 59(16)
Activating mutations of the RET proto-oncogene cause hereditary medullary thyroid carcinoma. To examine whether selective inactivation of mutant RET could prevent transformation, a hammerhead ribozyme was designed to cleave RET mRNA containing a tran
Autor:
R F, Gagel, I E, McCutcheon
Publikováno v:
The New England journal of medicine. 340(7)
Publikováno v:
Seminars in surgical oncology. 16(1)
Medullary thyroid carcinoma (MTC) is a unique disease in solid tumor oncology due to its ability to secrete calcitonin (iCT), a highly sensitive and specific serum marker of persistent or recurrent disease even at a microscopic level. The relatively
Publikováno v:
Current therapy in endocrinology and metabolism. 6